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Tracking how breast cancer spreads: Einstein receives $10M NIH grant
Date:6/19/2014

June 19, 2014 (BRONX, NY) The American Cancer Society predicts that 40,000 American women will die from breast cancer this year. Most of those deaths will occur due to cells from the primary tumor that spread to other parts of the bodythe process known as metastasis. Now, the National Cancer Institute, part of the National Institutes of Health (NIH), has awarded a $10 million grant to researchers at Albert Einstein College of Medicine of Yeshiva University to fund research into how breast cancer cells move and spread in the body, and how to predict which breast cancer tumors will metastasize.

"The main clinical problem is that there is no widely reliable test to determine the likelihood that metastasis will occur in an individual breast-cancer patient," said John Condeelis, Ph.D., the principal investigator on the grant. "Current tests focus on indirect measuressuch as biomarkers indicating the growth of the primary tumorthat are not directly related to metastasis. We're trying to change that." Dr. Condeelis is professor and co-chair of anatomy and structural biology, co-director of the Gruss Lipper Biophotonics Center and the Judith and Burton P. Resnick Chair in Translational Research at Einstein.

Over the past 10 years, Dr. Condeelis and his colleagues at the Tumor Microenvironment and Metastasis Program at the NCI-designated Albert Einstein Cancer Center, have studied how cancer cells move and spread. The researchers use intravital imaging, a technology that allows them to track individual cells and molecules moving within living animals in real time
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Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

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