Navigation Links
Tracking environmental causes of good and bad health
Date:10/25/2012

A Simon Fraser University scientist working at one of Canada's first epigenomics mapping centres says new federal funding will accelerate researchers' ability to unravel how we develop some of the most common life threatening cancers.

Through the Canadian Institutes of Health Research (CIHR), a granting agency that funds research, the federal government in partnership with Genome BC and Gnome Qubec is injecting $12 million into epigenetic research.

Distributed over five years, the funding will ramp up the operation of two newly established epigenomic mapping centres the first in Canada.

One centre is in Vancouver. It involves molecular biologists and biochemists Steven Jones, Martin Hirst, Marco Marra and Richard Moore at SFU, and researchers at Canada's Michael Smith Genome Sciences Centre (MSGSC) and the University of British Columbia. The other centre in Montreal involves researchers at McGill University and the Gnome Qubec Innovation Centre.

The centres' scientists are piecing together how constantly evolving chemical modifications in our DNA and proteins, known collectively as our epigenome, cause our genome to stay healthy or develop diseases. Initially, the researchers are investigating changes to tissues and cells that lead to Leukemia and cancers of the colon and ovaries. They are among the most common human malignancies.

"In contrast to our genome, which remains mostly the same throughout an individual's life," explains Hirst, "the epigenome changes during development and aging in response to external stimuli and emerging diseases."

The stimuli could be a variety of environmental factors, including exposure to chemical contaminants, dietary intake and social background such as poverty or a stimulating, nurturing setting.

"Epigenome changes over our life time can profoundly affect which genes are turned on and consequently how our cells behave," adds Hirst.

The SFU adjunct professor of molecular biology and biochemistry is also the head of epigenomics at the MSGSC. "Understanding which epigenome states exist in different cell types and how these states interact is critically important to discovering how human health and disease evolve."

As part of a broader international effort to generate 1,000 reference epigenomes, the mapping centres are generating 100 of them from primary human tissues and cells.

The new federal funding enables them to use high-through-put sequencing, such as the Illumina Hiseq platform, to do the DNA and protein analysis.


'/>"/>

Contact: Carol Thorbes
cthorbes@sfu.ca
778-782-3035
Simon Fraser University
Source:Eurekalert

Related medicine news :

1. Health Officials Tracking Salmonella Outbreak Linked to Pet Turtles
2. Cell-Based Tracking Devices Might Help Monitor Treatments
3. AFTS Labs Partners With Physicians To Complement NY's Mandated I-STOP Tracking System For Pain Pill Prescriptions: A Recipe For A Safer Community
4. Tracking the wave of success for Team GBs swimmers
5. Tracking Love, Lust in the Brain
6. Virtual boundaries: How environmental cues affect motivation and task-oriented behavior
7. Environmental Gene-Swapping May Play Part in Antibiotic Resistance
8. Jaeckle Fleischmann Environmental Attorneys Recover Additional $5 Million for Solvent Chemical
9. Stanford Woods Institute for the Environment announces 2012 Environmental Venture Project awards
10. Staying Home With Sick Kids Causes Job Worries for Parents: Survey
11. In obesity, a micro-RNA causes metabolic problems
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users can ... CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn ... X . Simply select a ProHand generator and drag it above media or text ...
(Date:6/25/2016)... ... , ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department ... in recognition of their exemplary accomplishments in worksite health promotion. , The Wellness at ... Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one of 42 ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World ... with chronic pain and the benefits of holistic treatments, Serenity Recovery Center ... with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the ...
(Date:6/24/2016)... ... 24, 2016 , ... Dr. Amanda Cheng, an orthodontist ... has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be used ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... at the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, ... journal articles published in Emergency Medicine Practice and Pediatric Emergency Medicine ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced the addition of ... report to their offering. ... kidney failure, it replaces the function of kidneys by removing ... thus the treatment helps to keep the patient body,s electrolytes ... Increasing number of ESRD patients & substantial healthcare expenditure ...
(Date:6/23/2016)... Research and Markets has announced the ... 2016 - Forecast to 2022" report to their offering. ... up to date financial data derived from varied research sources ... with potential impact on the market during the next five ... comprises of sub markets, regional and country level analysis. The ...
(Date:6/23/2016)... and INDIANAPOLIS , June ... receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is any ... scholarship winners, announced today online at www.diabetesscholars.org ... type 1 diabetes stand in the way of academic ... supported the Foundation,s scholarship program since 2012, and continues ...
Breaking Medicine Technology: