Navigation Links
Tracking Drug Levels Helps Pregnant Women With Epilepsy
Date:11/29/2007

Blood testing cuts down on seizures linked to lamotrigine use, research shows

THURSDAY, Nov. 29 (HealthDay News) -- Having doctors monitor blood levels of the drug lamotrigine in pregnant women with epilepsy can help reduce the number of seizures they experience, U.S. research shows.

Lamotrigine, an epilepsy drug, is taken by pregnant women with epilepsy because of its relatively mild risk of causing birth defects. However, the drug has also been linked to increased seizure activity in 75 percent of pregnancies, according to background information in the study.

This study, reported in the Nov. 28 online issue of Neurology, found that monitoring levels of lamotrigine in the blood helps reduce overall seizure activity associated with the drug. It also helps improves the overall health of mother and fetus, the researchers say.

"This is important data considering current treatment guidelines do not address how to dose epilepsy drugs once women become pregnant," study author Dr. Page B. Pennell, of the Emory University School of Medicine in Atlanta, said in a prepared statement.

The study included 53 women taking lamotrigine who underwent drug monitoring every one to three months during their pregnancies. Drug doses were adjusted depending on lamotrigine levels in the blood. The goal was to maintain each woman's target lamotrigine level based on pre-pregnancy information.

Among the women in the study, 39 had increased seizure activity during pregnancy, 33 percent had reduced seizure activity, and 28 percent had no change. The health of their babies was similar to that of babies born to women without epilepsy.

"These rates are more consistent with what's been reported for pregnant women with epilepsy using other medications, and show the effectiveness of drug monitoring," Pennell said. "Our findings provide a foundation for treatment guidelines to prevent increased seizure frequency and ultimately improve the health of the mother and fetus."

More information

The American Academy of Family Physicians has more about epilepsy and pregnancy.



-- Robert Preidt



SOURCE: American Academy of Neurology, news release, Nov. 28, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. System Planning Corporation Launches New Asset Tracking and Monitoring System to Meet Pharmaceutical Industry Needs
2. Pelosi, Slaughter and Tubbs Jones Introduce Health Tracking Legislation
3. Hospital Launches State-of-the-Art Patient Tracking and Integrated Patient Data System
4. Design of patient tracking tools may have unintended consequences
5. Adult offspring of parents with PTSD have lower cortisol levels
6. Study Demonstrates Marteks Algal DHA Oil Improves Blood Triglyceride Lipid Levels
7. Screening Proposed for Childhood Cholesterol Levels
8. Womens Folic Acid Levels Improving
9. Giving emergency nurses aromatherapy massages with music dramatically reduced stress levels
10. Giving emergency nurses aromatherapy massages with music dramatically reduced stress levels
11. School, family and community involvement are all needed to increase the activity levels of adolescen
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency ... named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. ... Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director ...
(Date:6/25/2016)... , ... June 25, 2016 , ... Conventional wisdom preaches ... success. In terms of the latter, setting the bar too high can result in ... than just slow progress toward their goal. , Research from PsychTests.com ...
(Date:6/24/2016)... ... 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out of ... verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. ... throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... is proud to recognize Dr. Barry M. Weintraub as a prominent plastic surgeon ... beautiful women in the world, and the most handsome men, look naturally attractive. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Research and Markets has announced the addition of ... report to their offering. ... The World Market for Companion Diagnostics covers the world market ... the report includes the following: , World ... Region (N. America, EU, ROW), 2015-2020 , World IVD ...
(Date:6/24/2016)...   Pulmatrix, Inc ., (NASDAQ: PULM ... announced today that it was added to the Russell ... comprehensive set of U.S. and global equity indexes on ... milestone for Pulmatrix," said Chief Executive Officer Robert ... progress in developing drugs for crucial unmet medical needs, ...
(Date:6/24/2016)...  Arkis BioSciences, a leading innovator in the ... cerebrospinal fluid treatments, today announced it has secured ... led by Innova Memphis, followed by Angel Capital ... Arkis, new financing will accelerate the commercialization of ... of its in-licensed Endexo® technology. ...
Breaking Medicine Technology: