Navigation Links
Toxins from Staph Bacteria Disrupt Immune System
Date:11/30/2010

TUESDAY, Nov. 30 (HealthDay News) -- Superantigens -- toxins produced by staphylococcus bacteria -- are more complex and may cause more illnesses than formerly realized, say Swedish researchers.

"Superantigens have a real talent for disrupting the body's immune system. If you're infected with bacteria that secrete antigens, your immune system will respond so strongly that it'll make you ill," study author Karin Lindkvist, of the University of Gothenburg, said in a university news release. "Our study shows that superantigens activate the immune system in more ways than previously thought."

A normal viral infection will trigger activation of about 0.0001 percent of the immune system's natural killer cells (a type of T-cell). But bacteria that secrete superantigens trigger activation of 5 percent to 20 percent of the body's T-cells, an immune response that often causes illness such as fever and extreme nausea.

"By investigating how superantigens activate the immune system via its T-cells, we've been able to show that they bind to more than one part of the T-cell receptor," Lindkvist said. "This is an important discovery for our understanding of superantigens' biological function, and for the future development of a vaccine against superantigens. We haven't yet looked at whether other superantigens can activate T-cells in the same complex way, but it's reasonable to assume that they can."

Staph infections are associated with food poisoning, wound infections and abscesses. Superantigens can also cause toxic symptoms and toxic shock syndrome, and some scientists have speculated that they are involved with autoimmune disorders such as rheumatoid arthritis.

The study appears in the current issue of the journal Nature Communications.

More information

The Nemours Foundation has more about staph infections.

-- Robert Preidt

SOURCE: University of Gothenburg, news release, Nov. 28, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Many Supplements Said to Contain Toxins, Make False Health Claims
2. UCI gets major funding to study ways of preventing drug-resistant staph infections
3. Drug-Resistant Staph Threatens Cystic Fibrosis Patients
4. ANY LAB TEST NOW Launches New Infectious Disease Panels - Affordable Panels Test for H1N1, Staph, E. coli and Other Infectious Diseases
5. Latest American Chemical Society podcast: New water filter kills disease-causing bacteria
6. Severe Bacterial Strain Found in Cystic Fibrosis Patients in Canada
7. Unexpectedly small effects of mutations in bacteria bring new perspectives
8. Common stomach bacteria may fight off inflammatory bowel disease caused by Salmonella
9. Knowledge gaps, fears common among parents of children with drug-resistant bacteria
10. Intestinal enzyme helps maintain population of beneficial bacteria
11. NIH scientists describe how salmonella bacteria spread in humans
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Toxins from Staph Bacteria Disrupt Immune System
(Date:10/12/2017)... ... 12, 2017 , ... The company has developed a suite ... regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been developed ... , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, Non-Dairy*, ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... HMP ... the recipient of a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B Healthcare ... City on October 11, 2017. , The annual award competition recognizes editorial and design ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... been named one of Michigan’s 2017 Best and Brightest in Wellness® by Best ... in Wellness® awards program on Friday, Oct. 20 from 7:30 a.m. to 2 ...
(Date:10/12/2017)... ... October 12, 2017 , ... Vohra Chief ... advancements to physician colleagues, skilled nursing facility medical directors and other clinicians at ... of Wound Care." , "At many of these conferences we get to educate ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... 2, 2017  Eli Lilly and Company (NYSE: ... the third quarter of 2017 on Tuesday, October 24, ... that day with the investment community and media to ... conference call will begin at 9 a.m. Eastern time. ... live webcast of the conference call through a link ...
(Date:9/28/2017)... , Sept. 28, 2017 Hill-Rom Holdings, ... 2017 earnings conference call and webcast on Friday, November ... a.m. (EDT) and ending at approximately 8:30 a.m. (CDT) ... discussing the company,s 2017 financial performance and guidance for ... opportunities, initiatives to enhance operational performance, and long-range financial ...
(Date:9/25/2017)...   Montrium , an industry leader in ... IQPC Trial Master Files & Inspection Readiness Conference ... Clinical Services has selected eTMF Connect ... EastHORN, a leading European contract research organization (CRO), ... to enable greater collaboration with sponsors, improve compliance ...
Breaking Medicine Technology: