Navigation Links
Toxins from Staph Bacteria Disrupt Immune System
Date:11/30/2010

TUESDAY, Nov. 30 (HealthDay News) -- Superantigens -- toxins produced by staphylococcus bacteria -- are more complex and may cause more illnesses than formerly realized, say Swedish researchers.

"Superantigens have a real talent for disrupting the body's immune system. If you're infected with bacteria that secrete antigens, your immune system will respond so strongly that it'll make you ill," study author Karin Lindkvist, of the University of Gothenburg, said in a university news release. "Our study shows that superantigens activate the immune system in more ways than previously thought."

A normal viral infection will trigger activation of about 0.0001 percent of the immune system's natural killer cells (a type of T-cell). But bacteria that secrete superantigens trigger activation of 5 percent to 20 percent of the body's T-cells, an immune response that often causes illness such as fever and extreme nausea.

"By investigating how superantigens activate the immune system via its T-cells, we've been able to show that they bind to more than one part of the T-cell receptor," Lindkvist said. "This is an important discovery for our understanding of superantigens' biological function, and for the future development of a vaccine against superantigens. We haven't yet looked at whether other superantigens can activate T-cells in the same complex way, but it's reasonable to assume that they can."

Staph infections are associated with food poisoning, wound infections and abscesses. Superantigens can also cause toxic symptoms and toxic shock syndrome, and some scientists have speculated that they are involved with autoimmune disorders such as rheumatoid arthritis.

The study appears in the current issue of the journal Nature Communications.

More information

The Nemours Foundation has more about staph infections.

-- Robert Preidt

SOURCE: University of Gothenburg, news release, Nov. 28, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Many Supplements Said to Contain Toxins, Make False Health Claims
2. UCI gets major funding to study ways of preventing drug-resistant staph infections
3. Drug-Resistant Staph Threatens Cystic Fibrosis Patients
4. ANY LAB TEST NOW Launches New Infectious Disease Panels - Affordable Panels Test for H1N1, Staph, E. coli and Other Infectious Diseases
5. Latest American Chemical Society podcast: New water filter kills disease-causing bacteria
6. Severe Bacterial Strain Found in Cystic Fibrosis Patients in Canada
7. Unexpectedly small effects of mutations in bacteria bring new perspectives
8. Common stomach bacteria may fight off inflammatory bowel disease caused by Salmonella
9. Knowledge gaps, fears common among parents of children with drug-resistant bacteria
10. Intestinal enzyme helps maintain population of beneficial bacteria
11. NIH scientists describe how salmonella bacteria spread in humans
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Toxins from Staph Bacteria Disrupt Immune System
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Lori R. ... a member of ElderCounsel, a national organization of elder law and special needs planning ... laws and rules. It also provides a forum to network with elder law attorneys ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance that ... insurance companies have a waiver for care if the client has a cognitive impairment ... family pays for care, is often waived, so the benefits from their insurance start ...
(Date:10/13/2017)... ... 2017 , ... Ellevate Network, the leading network for professional women, brought together ... equality at their inaugural Summit in New York City in June. The event was ... of over 3 million. To watch the Mobilize Women video, click here . ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The ... the most popular and least understood books in the Holy Scriptures, Revelation. The Book ... have baffled scholars for centuries. Many have tossed it off as mere rubbish, but ...
(Date:10/13/2017)... , ... October 13, 2017 , ... ... and Agile Software Development, has been awarded a contract by the Center for ... Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in a ...
Breaking Medicine News(10 mins):
(Date:10/5/2017)... 2017  In response to the nationwide opioid ... Surgeons (AAOMS) released prescribing recommendations that urge ibuprofen ... as a first-line therapy to manage a patient,s ... Recognizing the value and importance of ... Prescribing: Acute and Postoperative Pain Management" stresses that ...
(Date:10/4/2017)...  According to the Centers for Disease Control and Prevention (CDC), ... Urgent Care is helping communities across Massachusetts , ... offering no-cost* flu shots through the end of the month. ... regulations. ... a flu shot is by the end of October, according to the ...
(Date:10/2/2017)... -- Diplomat Pharmacy, Inc. (NYSE: DPLO ) ... , and named its founder as Diplomat,s chief information ... Tennessee , will operate under Diplomat subsidiary Envoy ... for health care partners to include IT outsourcing, consulting, ... "In an interoperable world, technology delivers comprehensive insight and ...
Breaking Medicine Technology: