Navigation Links
Toxins from Staph Bacteria Disrupt Immune System
Date:11/30/2010

TUESDAY, Nov. 30 (HealthDay News) -- Superantigens -- toxins produced by staphylococcus bacteria -- are more complex and may cause more illnesses than formerly realized, say Swedish researchers.

"Superantigens have a real talent for disrupting the body's immune system. If you're infected with bacteria that secrete antigens, your immune system will respond so strongly that it'll make you ill," study author Karin Lindkvist, of the University of Gothenburg, said in a university news release. "Our study shows that superantigens activate the immune system in more ways than previously thought."

A normal viral infection will trigger activation of about 0.0001 percent of the immune system's natural killer cells (a type of T-cell). But bacteria that secrete superantigens trigger activation of 5 percent to 20 percent of the body's T-cells, an immune response that often causes illness such as fever and extreme nausea.

"By investigating how superantigens activate the immune system via its T-cells, we've been able to show that they bind to more than one part of the T-cell receptor," Lindkvist said. "This is an important discovery for our understanding of superantigens' biological function, and for the future development of a vaccine against superantigens. We haven't yet looked at whether other superantigens can activate T-cells in the same complex way, but it's reasonable to assume that they can."

Staph infections are associated with food poisoning, wound infections and abscesses. Superantigens can also cause toxic symptoms and toxic shock syndrome, and some scientists have speculated that they are involved with autoimmune disorders such as rheumatoid arthritis.

The study appears in the current issue of the journal Nature Communications.

More information

The Nemours Foundation has more about staph infections.

-- Robert Preidt

SOURCE: University of Gothenburg, news release, Nov. 28, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Many Supplements Said to Contain Toxins, Make False Health Claims
2. UCI gets major funding to study ways of preventing drug-resistant staph infections
3. Drug-Resistant Staph Threatens Cystic Fibrosis Patients
4. ANY LAB TEST NOW Launches New Infectious Disease Panels - Affordable Panels Test for H1N1, Staph, E. coli and Other Infectious Diseases
5. Latest American Chemical Society podcast: New water filter kills disease-causing bacteria
6. Severe Bacterial Strain Found in Cystic Fibrosis Patients in Canada
7. Unexpectedly small effects of mutations in bacteria bring new perspectives
8. Common stomach bacteria may fight off inflammatory bowel disease caused by Salmonella
9. Knowledge gaps, fears common among parents of children with drug-resistant bacteria
10. Intestinal enzyme helps maintain population of beneficial bacteria
11. NIH scientists describe how salmonella bacteria spread in humans
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Toxins from Staph Bacteria Disrupt Immune System
(Date:6/26/2016)... ... June 26, 2016 , ... Pixel Film Studios Released ... , "Film editors can give their videos a whole new perspective by using the ... CEO of Pixel Film Studios. , ProSlice Levels contains over 30 Different presets ...
(Date:6/25/2016)... ... ... Austin residents seeking Mohs surgery services, can now turn to Dr. Jessica ... Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to include Mohs ... Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn Goldstein, ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... recover from injury. Recently, he has implemented orthobiologic procedures as a method for ... is one of the first doctors to perform the treatment. Orthobiologics are substances ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World ... with chronic pain and the benefits of holistic treatments, Serenity Recovery Center ... with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the ...
(Date:6/24/2016)... Diego, CA (PRWEB) , ... June 24, 2016 , ... ... with the American Cancer Society and the Road To Recovery® program to drive cancer ... to seniors and other adults to ensure the highest quality of life and ongoing ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... CHAPEL HILL, N.C. , June 24, 2016 ... in healthcare decisions and regulators/payers have placed more ... this new environment, patient support programs in the ... support for patients, medications. Consequently, pharmaceutical companies are ... to ensure they are providing products and services ...
(Date:6/24/2016)... CAMBRIDGE, Mass. , June 24, 2016 /PRNewswire/ ... the Spaulding Rehabilitation Network,s Dean Center for ... of Physical Medicine and Rehabilitation, MIT Hacking Medicine, ... Center for Innovation, today announced the five finalists ... Hackathon for Lyme disease.  More than 100 scientists, ...
(Date:6/24/2016)... 2016 The Academy of Managed Care Pharmacy ... that would allow biopharmaceutical companies to more easily share ... formulary and coverage decisions, a move that addresses the ... The recommendations address restrictions in the sharing ... drug label, a prohibition that hinders decision makers from ...
Breaking Medicine Technology: