Navigation Links
Toxin from brain cells triggers neuron loss in human ALS model
Date:2/6/2014

animal models of ALS.

New Human Cell Model of ALS Will Speed Identification of Potential Therapies

The development of new therapies for ALS has been disappointing, with more than 30 clinical trials ending with no new treatments since the 1995 FDA approval of riluzole.

The lack of progress may be partly because animal models used to study ALS do not completely recreate the human disease. The new all-human cell model of ALS created for the current study may improve scientists' ability to identify useful drug targets, particularly for the most common form of the disease.

"Although there are many neurodegenerative disorders, only for a handful do we have access to a simplified model that is relevant to the disease and can therefore potentially be used for high-throughput drug screening. So this model is quite special," Dr. Przedborski said. "Here we have a spontaneous disease phenotype triggered by the relevant tissue that causes human illness. That's one important thing. The other important thing is that this model is derived entirely from human elements. This is probably the closest, most natural model of human ALS that we can get in a dish."


'/>"/>

Contact: Karin Eskenazi
ket2116@columbia.edu
212-342-0508
Columbia University Medical Center
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. NIH-created toxin can kill HIV-infected cells that persist despite treatment
2. How to Sleep Away Harmful Brain Toxins Discussed in Health Nutrition News Video
3. Bel Marra Health Reports on Recent Research Revealing a Dangerous Toxin Linked to Increased Risk of Stroke
4. Research Report on Feed Mycotoxin Absorbent Market in China
5. Environmental toxins linked to heart defects
6. Diet Doc Hormone Diets & Weight Loss Plans Announces Detox Formula, Designed to Cleanse the Liver of Dangerous Toxins & Avoid Weight Loss Plateaus
7. Quality Treatment for Biotoxin Related Illness is Getting Easier to Find
8. Neurotoxin effectively relieves bone cancer pain in dogs, Penn researchers find
9. New Studies Linking Environmental Toxins to Infertility Validate Benefits of Fairhaven Health's FertileDetox
10. European Food Safety Testing Market (Pathogen, GMO, Toxin, Pesticide) Worth $4,068.8 Million by 2018 - New Report by MarketsandMarkets
11. Diet Doc Weight Loss Plans Announces New Detox Formula, Designed to Promote Safe and Rapid Weight Loss By Cleansing the Body of Harmful Toxins
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Toxin from brain cells triggers neuron loss in human ALS model
(Date:5/23/2015)... D.C. (PRWEB) May 23, 2015 On ... of powers of a youngster's yogic power learned through ... Sri Nithyananda Swami in Bangalore, India. , Yogamaatha, a ... more than 50 high profile professionals attending the 2015 ... by reading fluently -- blindfolded. , In a ...
(Date:5/23/2015)... 23, 2015 On May 16, the team ... event was a 5k mud obstacle run that raised funds ... million people worldwide, and the reason we participated was to ... Davis, owner of Farrell’s eXtreme Bodyshaping. “One-hundred percent of the ... , The event was not only attended by eXtreme Bodyshaping ...
(Date:5/23/2015)... May 23, 2015 Add High-Quality prismatic refractions ... Film Studios. , It's as simple as dragging and dropping ... included tool for full effect. , Including over 80 ... range 5k sensors making this the ultimate bundle for adding ... included in this package are movie files designed for Final ...
(Date:5/22/2015)... The American College of Traditional Chinese Medicine ... will hold a webinar on the updates of the ... Classical Chinese Medicine. , Webinar – First Professional Doctorate ... Dean of Clinical Education, will lead this webinar in ... program. ACTCM is currently developing this degree program based ...
(Date:5/22/2015)... 22, 2015 Following yesterday’s announcement that ... with US-based health brand Nature’s Way, Marc St-Onge has ... of Ascenta Skin is an integral part of the ... this opportunity to further develop Ascenta Skin into a ... Skin is a breakthrough, anti-aging skincare supplement featuring 6 ...
Breaking Medicine News(10 mins):Health News:Nine-Year-Old Reads Blindfolded at Business Advocacy Summit 2Health News:Nine-Year-Old Reads Blindfolded at Business Advocacy Summit 3Health News:Farrell’s eXtreme Bodyshaping Team Runs through the Muck for MS 2Health News:Developers at Pixel Film Studios Release ProFlare 5K Prism for Final Cut Pro X. 2Health News:ACTCM Announces Upcoming June Events 2Health News:Ascenta Skin President Announces Plans to Grow Brand 2
... will spread and so need aggressive treatment. Researchers at University ... a computer is taught to spot patterns //- in combination ... natural language. The result is a model which can scrutinize ... is the tumor will spread. ,Tested on samples ...
... 3 million Americans age 12 to 18 considered suicide in ... kill themselves, a government survey found. According to the on ... boys// to have thought about or tried to commit suicide. ... Mental Health Services Administration, showed that only one in three ...
... women who suffer from premenstrual syndrome, or PMS. A ... women who have exhausted all other medications without help.// ... Center in Philadelphia, set out to determine whether half-cycle ... is started 14 days prior to the start of ...
... liver oil followed by a chewy, multi-vitamin tablet with ... New studies show children with otitis media, or middle ... infections once they began taking vitamin/mineral supplements and cod ... omega-3 fatty acids. ,Otitis media is common and ...
... women with high levels of lead in their bones face ... lead from sources like old pain, researchers reported recently. In ... of lead exposure// “may constitute a significant public health problem, ... bone.” ,The findings demonstrated that protecting children from the ...
... being paid to enrol them in a clinical trial. Post-marketing ... part of medical research. It involves giving patients a new ... arise. The post-marketing phase will involve many more patients than ... be an important way of revealing uncommon side effects. ...
Cached Medicine News:
(Date:5/22/2015)... May 22, 2015  RegeneRx Biopharmaceuticals, Inc. (OTCQB: RGRX), ... repair and regeneration, today announced that J.J. Finkelstein ... present a corporate overview at two upcoming investor conferences. ... SeeThruEquity 4 th Annual Microcap Conference on Thursday ... at 11:00 am EDT.  A webcast will ...
(Date:5/22/2015)... OF PRUSSIA, Pa. , May 22, 2015  The ... Behring its 2015 Corporate Leadership Award as recognition for ... improving the care of the bleeding disorders community.  The award ... Director, CSL Limited, during the NHF Annual Spring Soiree in ... "The National Hemophilia Foundation is dedicated to finding ...
(Date:5/22/2015)... , May 22, 2015  The Mesothelioma ... diagnosed victims of mesothelioma get the best possible ... certain individuals with this rare cancer caused by ... most up-to-date information related to treatment options such ... please call the Mesothelioma Victims Center anytime at ...
Breaking Medicine Technology:RegeneRx to Present at 2 Investor Conferences 2RegeneRx to Present at 2 Investor Conferences 3National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 2National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 3National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 4Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 2Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 3Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 4Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 5
... 26, 2012  A minimally invasive treatment may target hunger ... to block arteries to the stomach and suppress hunger ... to repair vertebral disc degeneration. Initial results from all ... Radiology,s 37th Annual Scientific Meeting in San Francisco, Calif. ...
... Quest International, Inc., a leading global supplier of ... today that is has contributed $5000 to the American ... Cancer Society Key Gala, that benefits the Boston Hope ... Thursday, March 29, 2012. "We are pleased ...
Cached Medicine Technology:No Pain, No Gain: Weight Loss, Disc Disease Interventional Radiology Treatments Coming 2No Pain, No Gain: Weight Loss, Disc Disease Interventional Radiology Treatments Coming 3No Pain, No Gain: Weight Loss, Disc Disease Interventional Radiology Treatments Coming 4No Pain, No Gain: Weight Loss, Disc Disease Interventional Radiology Treatments Coming 5No Pain, No Gain: Weight Loss, Disc Disease Interventional Radiology Treatments Coming 6Quest International Donates $5000 to the American Cancer Society 2
... new Platinum 10 concentrator. The Platinum 10 ... you have come to expect from the ... attractive alternative to liquid systems. The Platinum ... LPM for high flow patients, and has ...
... ,AirSeps AirLife On-board Oxygen Concentrators were ... supplemental oxygen passengers and are still in ... the US governments FAA/STC approval for this ... commercial aircraft, AirSep set the standard years ...
... November 2005. Specifications, including colors, subject to ... lb (2.3 kg), FreeStyle by AirSep is ... for those patients who know no boundaries. ... FreeStyle captures the heart of what it ...
... Oxygen Concentrator is the most compact, lightweight ... lbs (4.5 kg), this unit was designed ... active oxygen patient., ,Operating as a ... of both an oxygen concentrator and an ...
Medicine Products: