Navigation Links
Toward unraveling the Alzheimer's mystery
Date:4/23/2014

Getting to the bottom of Alzheimer's disease has been a rapidly evolving pursuit with many twists, turns and controversies. In the latest crook in the research road, scientists have found a new insight into the interaction between proteins associated with the disease. The report, which appears in the journal ACS Chemical Neuroscience, could have important implications for developing novel treatments.

Witold K. Surewicz, Krzysztof Nieznanski and colleagues explain that for years, research has suggested a link between protein clumps, known as amyloid-beta plaques, in the brain and the development of Alzheimer's, a devastating condition expected to affect more than 10 million Americans by 2050. But how they inflict their characteristic damage to nerve cells and memory is not fully understood. Recent studies have found that a so-called prion protein binds strongly to small aggregates of amyloid-beta peptides. But the details of how this attachment might contribute to disease and approaches to treat it are still up for debate. To resolve at least part of this controversy, Surewicz's team decided to take a closer look.

Contrary to previous studies, they found that the prion protein also attaches to large fibrillar clumps of amyloid-beta and do not break them down into smaller, more harmful pieces, as once thought. This finding bodes well for researchers investigating a novel approach to treating Alzheimer's using prion-protein-based compounds to stop these smaller, toxic amyloid-beta pieces from forming, the authors conclude.
'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related medicine news :

1. MSU physicists push new Parkinsons treatment toward clinical trials
2. Autism Speaks study finds advances towards universal early screening
3. Toward fixing damaged hearts through tissue engineering
4. A Priceless Resolution: Take That First Step Toward Financial Security
5. Athletes “Toward Injury Prevention in Sports” TIPS Gets Going in Las Vegas
6. Toward lowering titaniums cost and environment
7. Diet Doc Hormone Diets & Weight Loss Plans Launches Monthly Diet Newsletter Geared Toward Keeping Patients Informed with Interesting Health News, Diet Tips & Recipe Ideas
8. Considerable gender, racial and sexuality differences in attitudes toward bisexuality
9. Shifting Toward Preventative Healthcare Models in the United States
10. PharmaFocus: HIV - R&D Strategies towards Cure and Prevention
11. Federal Grant of $275,000 Funds Study of Young Adult Attitudes Toward Flavored Tobacco
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2016)... ... , ... May 2016 – Lips may be a central feature on our ... numbers of clients now ask about lip plumping and primping techniques and want tips ... Advanced Dermatology P.C. , The trend is a national one, with 2.4 ...
(Date:5/26/2016)... CT; Scottsdale, AZ (PRWEB) , ... ... ... insights consultancy, Actûrus , is happy to announce the launch of ... thinking of the funnel model to reflect the dynamic landscape of modern ...
(Date:5/26/2016)... ... May 26, 2016 , ... Development Team of Pixel Film ... FCPX. , "This new layered style transition tool will keep a consistent flow to ... of Pixel Film Studios. , TranSweep is an all new layered style transition ...
(Date:5/26/2016)... Madeira Beach, Florida (PRWEB) , ... May 26, 2016 , ... ... island connected to the mainland by a single drawbridge, citizens formed an organization, Madeira ... increase already congested traffic and change the small town center to a high rise ...
(Date:5/26/2016)... ... May 26, 2016 , ... According to the Webster’s dictionary, a hippie is ... beauty products, one company is going against the norm with a line of all-natural ... star in the green space is proud to announce its latest retail partnership with ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... , May 25, 2016  Granger Diagnostics today ... test for wounds and infections. This test ensures ... and select viruses. The test requires only a ... David G. Bostwick , MD, ... to facilitate wound healing: "We are excited to ...
(Date:5/24/2016)... , May 24, 2016 ... Markt gebracht, die es Ärzten erlaubt, ihre Expertise ... behandeln: MDLinking kombiniert Live Streaming mit einer Instant-Messaging-Funktion ... zu kommunizieren. Mediziner in Europa, Afrika, Asien und ... bereits für die Plattform registriert. Information ...
(Date:5/24/2016)... ARANZ Medical  Ltd a specialist ... has been named the Coretex Hi-Tech Emerging Company of the ... Dr Bruce Davey , CEO of ARANZ Medical says, ... good to be recognised for the work we are doing ... in 35 countries around the world from Sub-Saharan Africa through ...
Breaking Medicine Technology: