Navigation Links
Toward unraveling the Alzheimer's mystery
Date:4/23/2014

Getting to the bottom of Alzheimer's disease has been a rapidly evolving pursuit with many twists, turns and controversies. In the latest crook in the research road, scientists have found a new insight into the interaction between proteins associated with the disease. The report, which appears in the journal ACS Chemical Neuroscience, could have important implications for developing novel treatments.

Witold K. Surewicz, Krzysztof Nieznanski and colleagues explain that for years, research has suggested a link between protein clumps, known as amyloid-beta plaques, in the brain and the development of Alzheimer's, a devastating condition expected to affect more than 10 million Americans by 2050. But how they inflict their characteristic damage to nerve cells and memory is not fully understood. Recent studies have found that a so-called prion protein binds strongly to small aggregates of amyloid-beta peptides. But the details of how this attachment might contribute to disease and approaches to treat it are still up for debate. To resolve at least part of this controversy, Surewicz's team decided to take a closer look.

Contrary to previous studies, they found that the prion protein also attaches to large fibrillar clumps of amyloid-beta and do not break them down into smaller, more harmful pieces, as once thought. This finding bodes well for researchers investigating a novel approach to treating Alzheimer's using prion-protein-based compounds to stop these smaller, toxic amyloid-beta pieces from forming, the authors conclude.
'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related medicine news :

1. MSU physicists push new Parkinsons treatment toward clinical trials
2. Autism Speaks study finds advances towards universal early screening
3. Toward fixing damaged hearts through tissue engineering
4. A Priceless Resolution: Take That First Step Toward Financial Security
5. Athletes “Toward Injury Prevention in Sports” TIPS Gets Going in Las Vegas
6. Toward lowering titaniums cost and environment
7. Diet Doc Hormone Diets & Weight Loss Plans Launches Monthly Diet Newsletter Geared Toward Keeping Patients Informed with Interesting Health News, Diet Tips & Recipe Ideas
8. Considerable gender, racial and sexuality differences in attitudes toward bisexuality
9. Shifting Toward Preventative Healthcare Models in the United States
10. PharmaFocus: HIV - R&D Strategies towards Cure and Prevention
11. Federal Grant of $275,000 Funds Study of Young Adult Attitudes Toward Flavored Tobacco
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/4/2015)... Louis, MO (PRWEB) , ... August 04, 2015 ... ... attorneys handling national talcum powder lawsuits filed against Johnson & Johnson report that ... Talcum powder lawyers provide regular news updates and cancer warning information ...
(Date:8/4/2015)... ... August 04, 2015 , ... ... digital press at its Denver facility that will usher in a new standard ... Lightning Labels more effectively meet its twin objectives of quality and ...
(Date:8/4/2015)... ... August 04, 2015 , ... ... for executives and technology professionals in healthcare and technology markets, today announced significant ... Department of Defense’s recently-announced Electronic Health Record (EHR) decision. The DOD related numbers ...
(Date:8/3/2015)... ... August 04, 2015 , ... ... an extensive line up of live courses for the month of August. , ... courses individually or by purchasing a Physical Therapy Flex package. Flex packages ...
(Date:8/3/2015)... ... 03, 2015 , ... Zeiter’s Septic now performs septic installations ... and operated business, Zeiter’s Septic has been serving the community for over 20 ... because of their continued training and perseverance to provide their customers with new ...
Breaking Medicine News(10 mins):Health News:Talcum Powder Lawsuits: Plaintiffs Suggest Middlesex County Transfer 2Health News:Talcum Powder Lawsuits: Plaintiffs Suggest Middlesex County Transfer 3Health News:Talcum Powder Lawsuits: Plaintiffs Suggest Middlesex County Transfer 4Health News:Lightning Labels Installs State-of-the-Art Digital Press 2Health News:Lightning Labels Installs State-of-the-Art Digital Press 3Health News:Coverage of DOD’s EHR Decision Reinforces Healthcare IT News’ Leadership 2Health News:Elite Online CE Provider Announces Schedule of Live Courses For Florida Physical Therapy Continuing Education 2Health News:Elite Online CE Provider Announces Schedule of Live Courses For Florida Physical Therapy Continuing Education 3Health News:Zeiter’s Septics Performs Affordable Septic Installations Throughout Livingston & Putnam Counties Effective Immediately 2Health News:Zeiter’s Septics Performs Affordable Septic Installations Throughout Livingston & Putnam Counties Effective Immediately 3
... San Francisco-to-Los Angeles ride May 31SAN FRANCISCO and LOS ... 41 states and 14 nations will stream out of ... Angeles as participants in the colorful and emotional AIDS/LifeCycle, ... expected to raise more than $10 million to support ...
... , , THURSDAY, May 28 (HealthDay News) -- A total ... motion in arthritic or deformed ankles has been approved ... Scandinavian Total Ankle Replacement (STAR) system is the first ... a surface of flexible plastic (polyethylene). , Total ankle ...
... PregnancyWHITE PLAINS, N.Y., May 28 Starting pregnancy at ... pregnancy is critical to giving a baby a healthy ... in response to new guidelines from the Institute of ... for the amount of weight a woman should gain ...
... in Independent CategoryNEW YORK, May 28 Prix ... development, has added a new recognition category to its 2009 ... Prix Galien USA are now being accepted at ... 1, 2009. For the first time, the Prix Galien USA ...
... Covers High-throughput, Anchorage-independent Assay for Screening Compounds for ... Falcon Genomics, Inc. announced today that it has ... the Company,s Cancer BioChip System (CBCS) for the ... a high-throughput in vitro setting with ...
... bacteria in the small intestine are both associated with ... in a new study in the June issue of ... & Sons on behalf of the American Association for ... also available online at Wiley Interscience ( www.interscience.wiley.com ). ...
Cached Medicine News:Health News:AIDS/LifeCycle 8 to Raise $10+ Million to Fight AIDS 2Health News:AIDS/LifeCycle 8 to Raise $10+ Million to Fight AIDS 3Health News:Ankle Replacement System Lets Feet Move 2Health News:New Guidelines to Fight Obesity in Pregnancy Issued 2Health News:New Guidelines to Fight Obesity in Pregnancy Issued 3Health News:Prix Galien USA Now Accepting Nominations for Premiere Biopharmaceutical Industry Award 2Health News:Falcon Genomics Awarded Patent for Innovative Cancer Test 2Health News:Intestinal bacteria associated with non-alcoholic fatty liver disease 2
(Date:8/3/2015)... , Aug. 3, 2015  Landauer, Inc. (NYSE: ... environmental radiation measurement and monitoring, outsourced medical physics services ... will release financial results for the fiscal third quarter ... 2015. The Company will also host ... 2015 at 9:00 a.m. Central Time (10:00 a.m. Eastern ...
(Date:8/3/2015)... and MINNEAPOLIS , ... BSX ) has become a significant shareholder and ... representative for Preventice Solutions for cardiology-related diagnostic and ... an important strategic milestone for Preventice Solutions," said ... Strategy Officer, co CEO, Preventice Solutions.  "We are ...
(Date:8/3/2015)... FLINT, Mich., Aug. 3, 2015 Diplomat Pharmacy, Inc. ... announced financial results for the quarter ended June 30, 2015. ... June 30, 2014. Second Quarter 2015 Highlights ... of 49% or $266 million , Total prescriptions dispensed ... of 8.6% versus 5.5% , Adjusted EBITDA of $22.7 ...
Breaking Medicine Technology:Landauer, Inc. Announces Date And Time For Announcement Of Fiscal Third Quarter 2015 Results And Conference Call 2Boston Scientific Announces Equity Investment And Sales Cooperation Agreement With Preventice Solutions 2Diplomat Announces 2nd Quarter 2015 Financial Results 2Diplomat Announces 2nd Quarter 2015 Financial Results 3Diplomat Announces 2nd Quarter 2015 Financial Results 4Diplomat Announces 2nd Quarter 2015 Financial Results 5Diplomat Announces 2nd Quarter 2015 Financial Results 6Diplomat Announces 2nd Quarter 2015 Financial Results 7Diplomat Announces 2nd Quarter 2015 Financial Results 8Diplomat Announces 2nd Quarter 2015 Financial Results 9Diplomat Announces 2nd Quarter 2015 Financial Results 10Diplomat Announces 2nd Quarter 2015 Financial Results 11Diplomat Announces 2nd Quarter 2015 Financial Results 12Diplomat Announces 2nd Quarter 2015 Financial Results 13Diplomat Announces 2nd Quarter 2015 Financial Results 14Diplomat Announces 2nd Quarter 2015 Financial Results 15Diplomat Announces 2nd Quarter 2015 Financial Results 16Diplomat Announces 2nd Quarter 2015 Financial Results 17Diplomat Announces 2nd Quarter 2015 Financial Results 18
... leading global organization focused on type 1 diabetes (T1D) ... Inc. (Nasdaq: DXCM ), a San Diego, ... continuous glucose monitoring (CGM) systems. The goal of the ... wireless "smart transmitter" that would allow a CGM system ...
... April 24, 2012  Mylan Inc. (Nasdaq: MYL ) ... final approval from the U.S. Food and Drug Administration (FDA) ... USP, 2.5 mg, 5 mg, 7.5 mg, 10 mg, 15 ... of Eli Lilly and Company,s Zyprexa ® , which is ...
Cached Medicine Technology:JDRF Announces Research Collaboration with Dexcom, Inc. to Develop "Smart Transmitter" Technology to Accelerate Artificial Pancreas Studies 2JDRF Announces Research Collaboration with Dexcom, Inc. to Develop "Smart Transmitter" Technology to Accelerate Artificial Pancreas Studies 3Mylan Launches Generic Version of Zyprexa® Tablets 2
Irrigating Capsulorhexis Cystotome. Formed angled tip, 27 g. Overall length 16 mm. 5/box....
Irrigating Capsulorhexis Cystotome. Formed blunt tip, 25 g. Overall length 22 mm. 5/box....
Irrigating Cystotome, formed, 25 g., 12 mm curved tip. Overall length 14 mm. 5/box....
Peribulbar Needle, 23 g. Atkinson style bevel. Overall length 31 mm. 5/box....
Medicine Products: