Navigation Links
Toward a fast, simple test for detecting cholera rampaging in 40 countries
Date:2/9/2011

With cholera on the rampage in Haiti and almost 40 other countries, scientists are reporting the development of a key advance that could provide a fast, simple test to detect the toxin that causes the disease. The report appears in ACS' journal Bioconjugate Chemistry. Cholera affects more than 200,000 people annually, mainly in developing countries, and causes about 5,000 deaths. Many involve infants, children, and the elderly.

J. Manuel Perez and colleagues note that cholera is an intestinal infection from food or water contaminated with the bacterium Vibrio cholerae. It produces a toxin that can cause severe diarrhea, which can lead to rapid dehydration and death. Prompt treatment thus is essential, and yet existing tests to diagnose cholera are time-consuming, expensive, and require the use of complex equipment.

The scientists describe a key advance toward a better, faster test. The new method uses specially prepared nanoparticles of iron oxide, each barely 1/50,000th the width of a single human hair, coated with a type of sugar called dextran. To achieve this, they looked for specific characteristics of the cholera toxin receptor (GM1) found on cells' surface in the victim's gut, and then they introduced these features to their nanoparticles. When the magnetic nanoparticles are added to water, blood, or other fluids to be tested, the cholera toxin binds to the nanoparticles in a way that can be easily detected by instruments. The test hardware can be turned into portable gear that health care workers could use in the field, the scientists say. The approach also shows promise for treating cholera intoxication.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related medicine news :

1. California Moves Toward Listing BPA as Reproductive Toxin
2. Advance Toward Test for Aggressive Prostate Cancer
3. Chocolate Industry Leaders Sign Agreement, Align on Path Towards Increasing Consumer Availability & Consistency of Beneficial Cocoa Flavanols
4. Fitness Trend Towards Online Personal Training Gets Real-World Weight Loss Results on FitOrbit.com
5. Electronic Health Information Leader Says Physician Practice Redesign is Vital Next Step Towards Safer, More Effective Care Delivery
6. Male batterers consistently overestimate rates of violence toward partners
7. New Research from EBRI: Older Workers Trending Toward More Part-Time Work
8. Miles for Hope’s Moving Towards A Cure(SM) Brain Tumor Walk in Boston Raising Funds for Brain Tumor Vaccine and Massachusetts General Hospital
9. Grassroots Campaign Drives toward Ending Malaria Deaths by 2015
10. PaperFree Florida to help move physicians towards electronic health records
11. SDI Reports: Pharmaceutical Promotion Spending Indicates Trend Toward Electronic and Online Promotion
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... 24, 2016 , ... Finally, a bruise cream that really works. Originally ... incorporated into the post-surgical treatment plans of a variety of other procedures including, but ... very effective for bruising and causes a rapid resolution of bruising and inflammatory changes ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Markarian, DDS, are co-chairs for the Illinois State Dental Society (ISDS) Foundation’s Mission ... at the Gateway Convention Center in Collinsville. , They expect to ...
(Date:6/24/2016)... ... 24, 2016 , ... SpiritQuest Sedona Retreats, located in Arizona has re-located to ... vortex sites: Cathedral Rock, Airport Mesa, and Boynton Canyon. The new retreat center ... as well as the Sedona Rouge, both popular accommodations for SpiritQuest clients. The ...
(Date:6/23/2016)... Colo., USA (PRWEB) , ... June 23, 2016 ... ... and Sanquin Blood Supply Foundation, a not-for-profit organization responsible for clinical transfusion research ... of patient enrollment for the Pathogen Reduction Evaluation and Predictive Analytical Rating Score ...
(Date:6/23/2016)... ... June 23, 2016 , ... vcfo, a consulting firm that ... to announce the promotion of Mike Mackey to Regional Vice President of Southeast ... was responsible for managing client projects and overseeing vcfo financial consultants in the ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, ... (Oral, Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is ... a CAGR of 6.1% in the forecast period 2016 ...
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Issue 52" report to their offering. ... treatment creates a favourable commercial environment for MedImmune to enter. ... base that will serve to drive considerable growth for effective ... serve to cap sales considerably, but development is still in ...
(Date:6/23/2016)... 2016 Revolutionary technology includes multi-speaker ... , industry leaders in advanced audiology and hearing aid ... Opn ™, the world,s first internet connected hearing aid ... devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ) ... of ,world firsts,: , TwinLink™ - the ...
Breaking Medicine Technology: