Navigation Links
Topical Cream for Erectile Dysfunction Shows Promise
Date:9/18/2009

It could become alternative for men who can't tolerate pills, researchers say

FRIDAY, Sept. 18 (HealthDay News) -- A topical cream for erectile dysfunction shows promise in animal testing and could become an alternative for men who can't tolerate the pill form of the drugs, U.S. researchers report.

Oral erectile dysfunction (ED) drugs, which belong to a class of medications called phosphodiesterase 5 (PDE5) inhibitors, are widely used and highly effective but can cause such side effects as headache, upset stomach, nasal congestion, facial flushing and hearing and vision problems. Men who've recently had a heart attack or have severe heart disease have to use oral ED drugs with caution, if at all.

The new cream consists of nanoparticles that can carry drugs or other substances, such as nitric oxide, and deliver them in a controlled and sustained manner, according to the researchers, who are from Albert Einstein College of Medicine at Yeshiva University in New York City. Nitric oxide is the signaling molecule that dilates blood vessels responsible for creating an erection.

The nanoparticle therapy was tested on 18 rats bred to have age-related ED. Some rats received nanoparticles with nitric oxide, others received nanoparticles with nitric oxide plus an experimental ED drug called silorphin (which has a different mechanism of action than PDE5 inhibitors) and a third group of rats received nanoparticles with nitric oxide and the PDE5 inhibitor tadalafil (Cialis).

Five of seven of the rats that received nanoparticles with nitric oxide and all 11 rats that received nanoparticles with nitric oxide and either silorphin or tadalafil showed significant improvements in erectile function.

"The response time to the nanoparticles was very short, just a few minutes, which is basically what people want in an ED medication," study co-author Dr. Joel M. Friedman, a professor of physiology, biophysics and medicin
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. FDA extends review of Pennsaid(R) diclofenac sodium topical solution
2. Paper Highlights Antimicrobial Effectiveness of Medical-Grade Honey in Topical Wound Care
3. Transdel Pharmaceuticals Completes Enrollment in Phase 3 Clinical Study for Novel Topical Pain Treatment
4. Bausch & Lomb Receives FDA Approval of Besivance(TM), New Topical Ophthalmic Antibacterial for the Treatment of Bacterial Conjunctivitis (Pink Eye)
5. Echo Therapeutics Licenses Needle-Free Prelude SkinPrep System to Ferndale Pharma for Enhanced Delivery of Topical Lidocaine
6. Watson Launches GELNIQUE(TM) (oxybutynin chloride) Gel 10%, First and Only Topical Gel for Overactive Bladder (OAB)
7. Clinical Topicals Makes Breakthrough Migraine Treatment Available Free to Soldiers
8. U.S. Study Shows Significant Improvement for Patients Suffering from Excessive Sweating with Topical Antiperspirant
9. Topical cream studied as way to treat skin cancer without the knife
10. Summit VetPharm Offers New Flea Topical Vectra for Dogs & Puppies(TM) For Long-Lasting Protection
11. New Topical Painkiller Relieves Severe Pain in Minutes
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Topical Cream for Erectile Dysfunction Shows Promise
(Date:4/14/2014)... orphaned by HIV/AIDS in South Africa may provide insight ... behavior issues in other areas of the world, which ... that could lead to successful interventions. , A ... United Nations mentions that due to the HIV/AIDS pandemic, ... African, children are at an increased risk for mental ...
(Date:4/14/2014)... A new study shows that moderate to severe ... risk of stroke, cancer and death. , Results of ... to severe obstructive sleep apnea were four times more ... times more likely to have a stroke (HR = ... (HR = 3.4), and 2.5 times more likely to ...
(Date:4/14/2014)... Dallas study involving serious youth offenders, the answer to one ... seven years: "How long do you think you,ll live?", According ... offending over time., Author Dr. Alex Piquero said the study ... of them offend at very high rates and commit more ... much later in life offend much less., "In a lot ...
(Date:4/14/2014)... with symptoms increasing dramatically during some of the most important ... has found. , Depressive symptoms increased on average by 68 ... young men, who were around 25 years old when they ... their children. The results of the study were published April ... is the first to identify when young fathers are at ...
(Date:4/14/2014)... Lower weight babies and babies who aren,t breastfed ... risk of developing chronic inflammation and related health ... study. , "There were good reasons to hypothesize ... inflammation in adulthood," says Thomas McDade (Northwestern University), ... in the Child & Brain Development program. "It ...
Breaking Medicine News(10 mins):Health News:Researchers identify children with emotional behavior difficulties 2Health News:Researchers identify children with emotional behavior difficulties 3Health News:Study links severe sleep apnea to increased risk of stroke, cancer and death 2Health News:UT Dallas study: Youth who fail to envision future commit more crimes 2Health News:Young dads at high risk of depression, too 2Health News:Low birth weight, less breastfeeding create later health risks 2
... , THURSDAY, April 28 (HealthDay News) -- Rising rates ... are cause for concern because excess weight is associated ... says. In people with arthritis, obesity is associated ... life, total joint replacement and poor outcomes after joint ...
... DC (April 28, 2011)Studies have shown that stress can ... against infection and disease. In cancer patients this ... and spread. However, the biological mechanisms that underlie ... Fox Chase Cancer Center find that poor psychosocial functioning ...
... 28 (HealthDay News) -- Use of a costly breast ... by what Medicare will pay for the treatment and ... Researchers analyzed Medicare data for 26,163 women with ... between 2001 and 2005. During that time, Medicare billing ...
... Goodwin HealthDay Reporter , THURSDAY, April 28 ... fill out while waiting to see their child,s ... suggests. Researchers recruited 137 pediatricians in the San ... screening test to fill out before seeing the doctor. ...
... (CTSN) at Emory University are focusing on prairie voles ... drugs to treat autism. They are starting ... behavioral therapy for phobias and also promotes pair bonding ... thought to facilitate learning and memory, can encourage them ...
... 2011 A program which combines interval training and ... those suffering from obesity, according to the results of ... for preventive medicine and physical activity (PIC Centre). Results ... Summit, currently taking place in Montreal. Within the ...
Cached Medicine News:Health News:Rising Obesity Rates Add to Arthritis Woes in U.S. 2Health News:Stress and depression are associated with shorter survival in head and neck cancer patients 2Health News:Payment Rates May Affect Breast Cancer Treatment 2Health News:Quick Screening May Help Spot Autism in Babies 2Health News:Quick Screening May Help Spot Autism in Babies 3Health News:Social bonding in prairie voles helps guide search for autism treatments 2Health News:Social bonding in prairie voles helps guide search for autism treatments 3Health News:Obesity: Conclusive results for the Montreal Heart Institute's EPIC Centre Kilo-Actif program 2
(Date:1/15/2014)... 2014 As health officials across the Midwest ... select Meijer pharmacies in Michigan ... throat to eligible patients, enabling Meijer pharmacists to administer ... under strict protocol set by a physician participating in ... Mich. -based retailer is collaborating with Ferris State ...
(Date:1/15/2014)... , Jan. 15, 2014 Massachusetts ... (NASDAQ: AMGN ) announced today that ... discover and validate new therapeutic targets and develop ... chronic disorder that affects millions worldwide. The MGH-Broad-Amgen ... medicine, IBD biology, human genetics, genomic technology, and ...
(Date:1/15/2014)... 2014  Manufacturers, suppliers and distributors of ... able to protect their most important business ... http://photos.prnewswire.com/prnh/20130716/CL46586LOGO ) Because ... Device Industry, it steadfastly remains one of ... involving IP infringement. This litigious nature can ...
Breaking Medicine Technology:Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4Intellectual Property Insurance for Medical-related Products and Services 2
... for an AI Over Tamoxifen in,a Single Trial ... Analysis of the entire,population of a single trial ... be significantly improved by switching from,tamoxifen to anastrozole ... study, published online in The,Journal of Clinical Oncology, ...
... - Novelos,Therapeutics, Inc. (OTCBB: NVLT), a biopharmaceutical ... treat cancer and,hepatitis, today announced encouraging results ... 2 trial of NOV-002,in combination with carboplatin ... patients were evaluable for best,overall tumor response ...
Cached Medicine Technology:Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal,Women with Early Breast Cancer Receiving Treatment with Tamoxifen 2Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal,Women with Early Breast Cancer Receiving Treatment with Tamoxifen 3Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal,Women with Early Breast Cancer Receiving Treatment with Tamoxifen 4Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal,Women with Early Breast Cancer Receiving Treatment with Tamoxifen 5Novelos Therapeutics Announces Encouraging Results in Ongoing Phase,2 Ovarian Cancer Trial at Dana-Farber/Partners Cancer Care 2Novelos Therapeutics Announces Encouraging Results in Ongoing Phase,2 Ovarian Cancer Trial at Dana-Farber/Partners Cancer Care 3
Latex agglutination inhibition slide test for the qualitative detection of hCG in urine....
Test for the quantitative determination of antideoxyribonuclease-B (ADNase-B) in serum....
Hemagglutination slide test for the qualitative and quantitative detection of Rheumatoid Factor in serum or synovial fluid....
Latex agglutination slide test for the qualitative or semi-quantitative detection of infectious mononucleosis heterophile antibodies in serum or plasma....
Medicine Products: