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Top research highlighted in fight against heart disease and stroke
Date:12/21/2010

insight into future progress

Several studies this year brought the future of medicine closer to the present with new insight into emerging technologies. Findings from stem cell therapy have shown improved quality of life and survival in several early studies of patients with chronic heart failure and support the development of future cell-based therapeutics. A large animal study defined the basic mechanisms for heart muscle regeneration initiated by specific types of stem cells. The results demonstrated that these stem cells repair scarred myocardium through promotion of the generation of new heart muscle and blood vessel). A second study supported the notion that the heart has the capacity to regenerate large numbers of heart muscle cells several times during its lifetime. Being able to directly reprogram stem cells into working heart muscle is a big step toward use in therapeutic settings. The STaR-Heart Study showed that injecting the patient's own bone marrow stem cells into the heart improved hemodynamics and long-term survival in the treatment of chronic heart failure

  • Hatzistergos, et al Circulation Research, July 29, 2010; Circ Res.;107(7):913-22. http://circres.ahajournals.org; Funding: National Heart, Lung, and Blood Institute.
  • Kajstura et al Circulation Research, June 3, 2010; Circ Res;107(2):305-15. http://circres.ahajournals.org; Funding: National Institutes of Health.
  • The STAR-heart study European Journal of Heart Failure; doi:10.1093/eurjhf/hfq095; Funding: Cardiogenesis Corporation.

9. Using science to support healthy lifestyle behaviors

New science examining lifestyle behaviors in adults and children, with particular emphasis on physical activity and consumption pattern, show that such conditions as obesity and hypertension are positively influenced by a change in diet with decreasing sodium level
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