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Top Scientists Explore the Origin of Life in Annual Lasker Lecture at Scripps Research Institute Florida Campus
Date:3/17/2010

livery systems, too?"

Paegel explained that conventional methods for generating molecular compartments aren't terribly effective. To solve that problem, he and Scripps Research scientist Gerald Joyce of The Scripps Research Institute's La Jolla, California, campus perfected a microfluidic processor designed to control the synthesis of these basic membrane structures and create a platform to observe molecular evolution in real time.

Paegel's innovative device used a replicating molecule that stitched together strands of RNA. After just 70 hours of replication, the molecule could duplicate RNA 90 times more efficiently than it did at the beginning, a clear confirmation of the power of evolution.

The study, "Darwinian Evolution on a Chip," was published in the journal Public Library of Science in April 2008.

SOURCE Albert and Mary Lasker Foundation

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SOURCE Albert and Mary Lasker Foundation
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