Navigation Links
Top-Line Data Available from Three Ipilimumab Pivotal Trials in Patients with Advanced Metastatic Melanoma
Date:12/10/2007

Initiation of the ipilimumab registrational monotherapy program reviewed under SPA with the FDA was announced in March 2006. Following the March 2006 announcement, enrollment of 487 patients was completed in less than one year and in line with timeline expectations. In December 2006, ipilimumab received Fast Track designation from the FDA for use as a monotherapy in previously treated patients with metastatic melanoma.

About Ipilimumab

Ipilimumab is a fully human antibody that binds to CTLA-4 (cytotoxic T lymphocyte-associated antigen 4), a molecule on T-cells that plays a critical role in regulating natural immune responses. The absence or presence of CTLA- 4 can augment or suppress the immune system's T-cell response in fighting disease. Ipilimumab is designed to block the activity of CTLA-4, thereby sustaining an active immune response in its attack on cancer cells.

Comprehensive Clinical Trial Program for Ipilimumab

Ipilimumab is being developed through a joint partnership between Bristol- Myers Squibb and Medarex. Based on nonclinical and clinical studies showing that antibody blockade of CTLA-4 plays an important role in sustaining an active immune response to fight cancer, Bristol-Myers Squibb and Medarex are pursuing a broad clinical development program with ipilimumab evaluating its potential use in advanced metastatic melanoma, as well as prostate, lung, pancreatic, bladder, breast, lymphoma and leukemia cancers. More than 2,000 patients have been treated with ipilimumab as a monotherapy or in combination with other agents in clinical trials.

For further information about ipilimumab clinical trials, please visit http://www.clinicaltrials.gov.

About Advanced Melanoma

Melanoma is a form of skin cancer characterized by the uncontrolled growth of pigment-producing cells (melanocytes) located in the skin. As with many cancers, it is more difficult to treat
'/>"/>

SOURCE Bristol-Myers Squibb Company; Medarex, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Evotec Reports Positive Top-Line Results in Phase II Study With EVT 201 in Elderly Insomniacs With Daytime Sleepiness
2. College Mental Health Expert and Sister of Student Who Died By Suicide Available to Discuss College Mental Health Issues
3. Multi-Year Compendium of Pharmaceutical Case Studies Available from Best Practices, LLC
4. Tickets Still Available for Detroit Uncorked;
5. Proven Terumo Coronary Guidewire Technology Is Now Available in the United States
6. Experts, Advocates Available to Comment on Hillary Clintons Health Care Plan
7. Fingertip Formulary Mobile(TM) is Now Available for Physicians and Other Healthcare Providers Free on PDAs
8. New Resource for Taking Care of Aging Parents Available in Beta
9. 2007/2008 Pharmaceutical R&D Factbook Published by CMR International is Now Available
10. Morris Animal Foundation 2008 Sponsorship Guide Available, Details Current Animal Health Studies
11. Updated Brochure on Gynecologic Cancer Treatments Now Available
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2015)... (PRWEB) April 18, 2015 Carinsurancehints.com has released ... insurance plans that offer financial protection against fire damage. ... will pay benefits in case their vehicle is set intentionally ... vandalism caused by rioting or by other things. , ... quotes on a single website http://www.carinsurancehints.com/ , in ...
(Date:4/18/2015)... PITTSBURGH, PA (PRWEB) April 18, 2015 ... so I decided to create a healthful juice ... an inventor from Rosedale, Md. "It increases my ... overall healthy body." , He developed Tapp's Juice ... The juice helps to prevent physical and mental ...
(Date:4/18/2015)... April 18, 2015 Insuranceautoquote.info has released ... online auto insurance quotes . , Clients can ... single website. The online environment provides important advantages for ... , Drivers who do not have coverage for ... during any season, day or hour. Many agencies offer ...
(Date:4/18/2015)... has released a new blog post explaining how to ... , Drivers can find accurate information about various auto ... website can help drivers compare the newest and best ... whole process is designed to be convenient, free and ... quotes is advantageous because it allows clients to find ...
(Date:4/18/2015)... 2015 Thousand of DePuy Pinnacle hip ... individuals who were allegedly harmed by a metal-on-metal version ... in the U.S. District Court, Northern District of Texas. ... has amended an earlier Case Management Order to allow ... the new amendment permits the claims of up to ...
Breaking Medicine News(10 mins):Health News:Online Auto Insurance Quotes For Plans That Cover Fire Damages! 2Health News:Clients Can Review Car Insurance Quotes Online To Find Low Cost Offers! 2Health News:Auto Insurance Quotes Can Provide Accurate Results! 2Health News:DePuy Pinnacle Hip Lawsuits: Federal Litigation Amends Case Management Order to Allow for Joinder of Unrelated Claims 2Health News:DePuy Pinnacle Hip Lawsuits: Federal Litigation Amends Case Management Order to Allow for Joinder of Unrelated Claims 3
... www.mobilemassageteam.com ), a leading provider of on-site seated ... affairs, today announced that the company will be a sponsor ... ( http://www.globalfit.com/summit/ ) held on Thursday, ... City Philadelphia. Team members will be set up on ...
... Fight Against Tobacco Recognized Nationally -WASHINGTON, May 6 ... has been named the National Youth Advocate of the Year ... the fight against tobacco. Emily is being honored at a ... regional winners and a group winner. (Logo: ...
... released today by Ernst Berndt and Mark Trusheim of ... that eliminating FDA,s preemption protection would decrease patients, access ... reduce medical device industry employment. The paper, ... Devices on Patients, Innovation and Jobs," comes as ...
... Symmetry Medical Inc. (NYSE: SMA ), a leading ... and other medical markets, announced today that Brian S. Moore, ... Vice President and Chief Financial Officer, are scheduled to present ... Conference at the Palace Hotel in New York City on ...
... Performance athletes need to know their blood lactate level. ... their blood as a result of physical exertion and ... athletes therefore regularly have to attend performance diagnosis sessions. ... of exertion, a doctor takes blood samples from an ...
... May 6 /PRNewswire-Asia-FirstCall/ -- BMP Sunstone,Corporation (Nasdaq: BJGP ) (,BMP ... , -- Oppenheimer 3rd Annual China Dragon Call Conference, ... Madison Avenue in New York City. Management is currently, ... at 8:30, am ET on Tuesday, ...
Cached Medicine News:Health News:Campaign for Tobacco-Free Kids Honors Emily Kile, Greenfield, IN, as National Youth Advocate of the Year 2Health News:Removing Medical Device Preemption Impacts Jobs, Health Care Costs, Patient Access 2Health News:Symmetry Medical to Present at Bank of America and Merrill Lynch 2009 Healthcare Conference 2Health News:Lactate test made easy 2
(Date:4/17/2015)... 17, 2015  Regulatory leaders in the pharmaceutical industry ... draft called "21 st Century Cures." ... taken up by Congress soon and if enacted into ... products are developed and marketed in the ... have begun to consider how the proposed changes could ...
(Date:4/17/2015)... 2015 LifeScienceIndustryResearch.com announces having ... on Global and China Lysine Industry to its ... and the deep research report in this field. ... information including definition, classification specifications, application, industry chain ... Europe , Japan ...
(Date:4/17/2015)... Research and Markets ( http://www.researchandmarkets.com/research/6tdwh8/medical_device ... "Medical Device Outsourcing - Global Strategic Business Report" ... report analyzes the worldwide markets for Medical Device ... Categories: Class I, Class II, and Class III. ... Include - Radiology, Orthopedic, Neurology, Cardiology, and Others. ...
Breaking Medicine Technology:21st Century Cures: A Regulatory Game-Changer for the Pharmaceutical Industry 2Lysine Market International (US, Europe, Japan) Research Analysis 2Lysine Market International (US, Europe, Japan) Research Analysis 3Lysine Market International (US, Europe, Japan) Research Analysis 4Lysine Market International (US, Europe, Japan) Research Analysis 5Medical Device Outsourcing (Radiology, Orthopedic, Neurology, Cardiology, and Others) Market 2015 - Global Strategic Business Report 2Medical Device Outsourcing (Radiology, Orthopedic, Neurology, Cardiology, and Others) Market 2015 - Global Strategic Business Report 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: