Navigation Links
Too much vitamin D can be as unhealthy as too little
Date:5/29/2012

Scientists know that Vitamin D deficiency is not healthy. However, new research from the University of Copenhagen now indicates that too high a level of the essential vitamin is not good either. The study is based on blood samples from 247,574 Copenhageners. The results have just been published in the reputed scientific Journal of Clinical Endocrinology and Metabolism.

Vitamin D is instrumental in helping calcium reach our bones, thus lessening the risk from falls and the risk of broken hips. Research suggests that vitamin D is also beneficial in combating cardiac disease, depression and certain types of cancers. The results from a study conducted by the Faculty of Health and Medical Sciences now support the benefits of vitamin D in terms of mortality risk. However, the research results also show higher mortality in people with too high levels of vitamin D in their bloodstream:

"We have had access to blood tests from a quarter of a million Copenhageners. We found higher mortality in people with a low level of vitamin D in their blood, but to our surprise, we also found it in people with a high level of vitamin D. We can draw a graph showing that perhaps it is harmful with too little and too much vitamin D," explains Darshana Durup, PhD student.

If the blood contains less than 10 nanomol (nmol) of vitamin per liter of serum, mortality is 2.31 times higher. However, if the blood contains more than 140 nmol of vitamin per liter of serum, mortality is higher by a factor of 1.42. Both values are compared to 50 nmol of vitamin per liter of serum, where the scientists see the lowest mortality rate.

More studies are needed

Darshana Durup emphasises that while scientists do not know the cause of the higher mortality, she believes that the new results can be used to question the wisdom of those people who claim that you can never get too much vitamin D:

"It is important to conduct further studies in order to understand the relationship. A lot of research has been conducted on the risk of vitamin D deficiency. However, there is no scientific evidence for a 'more is better' argument for vitamin D, and our study does not support the argument either. We hope that our study will inspire others to study the cause of higher mortality with a high level of vitamin D," says Darshana Durup. She adds:

"We have moved into a controversial area that stirs up strong feelings just like debates on global warming and research on nutrition. But our results are based on a quarter of a million blood tests and provide an interesting starting point for further research."

The largest study of its kind

The study is the largest of its kind and it was only possible to conduct it because of Denmark's civil registration system, which is unique in the Nordic countries. The 247,574 blood samples come from the Copenhagen General Practitioners Laboratory:

"Our data material covers a wide age range. The people who participated had approached their own general practitioners for a variety of reasons and had had the vitamin D level in their bloodstream measured in that context. This means that while the study can show a possible association between mortality and a high level of vitamin D, we cannot as yet explain the higher risk," explains Darshana Durup.

Therefore in future research project scientists would like to compare the results with information from disease registers such as the cancer register. Financial support is currently being sought for such projects.


'/>"/>

Contact: Darshana Durup, Ph.D.
dd@farma.ku.dk
01-145-617-05192
University of Copenhagen
Source:Eurekalert

Related medicine news :

1. Japanese-American Men With Low Vitamin-D Diet Face Higher Stroke Risk
2. Vitamin C improves lung function in newborns of pregnant smoking women
3. Vitamin C improves pulmonary function in newborns of pregnant smoking women
4. Vitamin D + TB vaccine: Allies in fight against bladder cancer?
5. Experts call for clinical trials to test non-skeletal benefits of vitamin D
6. Vitamin K2: New hope for Parkinsons patients?
7. Researchers determine vitamin D blood level for reducing major medical risks in older adults
8. Vitamin E in diet protects against many cancers
9. Vitamin E Supplements Dont Affect Heart Failure Risk: Study
10. Lack of Vitamin D May Harm Older Womens Health
11. Vitamin D deficiency linked to higher mortality in female nursing home residents
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2017)... Illinois (PRWEB) , ... May 28, 2017 , ... ... , a medical scrubs and uniform distributor based in Lima, Ohio. The sale began ... features approximately one million units of medical garments, scrubs, uniforms, and medical accessories, including ...
(Date:5/27/2017)... (PRWEB) , ... May 26, 2017 , ... A May ... who visit a doctor for colds or respiratory issues that are not responsive to ... time pressure on doctors may be largely responsible for the problem both in Canada ...
(Date:5/27/2017)... (PRWEB) , ... May 27, 2017 , ... Most us ... concern, but a new study from the Osteoarthritis Initiative shows that certain ... knee osteoarthritis. Knowing this in advance may give doctors the opportunity to treat patients ...
(Date:5/26/2017)... ... May 26, 2017 , ... ... new educational seminar to focus on current legislative activity and the latest regulatory ... at 1 p.m. Sunday, Sept. 10, and will continue through Monday, Sept. 11, ...
(Date:5/26/2017)... ... May 26, 2017 , ... Boar’s Head Brand®, one ... for Memorial Day entertaining that are sure to satisfy your guests’ flavor cravings, ... meats and cheeses featured in these refreshingly balanced recipes are packed with flavor, ...
Breaking Medicine News(10 mins):
(Date:5/4/2017)... Fix Inc. (" Fortuna "), a private, clinical-stage biotech ... need for embryonic and fetal stem cells by using direct ... Fortuna announced today the launch of its Scientific ... PhD; Father Kevin FitzGerald , S.J., PhD; Col. (R) ... Giordano , PhD. "We are excited and honored ...
(Date:5/4/2017)... , May 4, 2017  DarioHealth Corp. (NASDAQ: ... health and big data solutions, today announced that it ... Company, and STI Technologies Limited to lower diabetes healthcare ... Through STI,s innoviCares card, which is available throughout all ... DarioHealth customers will be eligible for additional savings when ...
(Date:5/3/2017)... May 3, 2017  Kalorama Information notes that ... percent next year and this is projected to ... stem cell (HSCT) or bone marrow transplants require ... are well-suited for this task. This according to ... Kalorama Information. The various PCR-based methodologies, Sanger sequencing ...
Breaking Medicine Technology: