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Too Much Sitting May Lower Odds of Surviving Colon Cancer
Date:1/23/2013

By Steven Reinberg
HealthDay Reporter

TUESDAY, Jan. 22 (HealthDay News) -- People diagnosed with colorectal cancer who spend a lot of their leisure time sitting have a higher risk of dying, according to researchers at the American Cancer Society.

People who are physically active, however, have a better chance of surviving than those who aren't, the researchers said.

"One factor might be that people who are physically active might be developing a less aggressive tumor," said lead researcher Peter Campbell, director of the society's Tumor Repository.

In addition, being physically fit may help people as they undergo treatment, he said.

Exercise improves cardiovascular and muscle fitness, lowers blood pressure and cholesterol, and improves blood sugar, Campbell noted. "Some of these factors would lead quite clearly to better tolerance for getting through surgery or other treatments," he said.

Campbell said the connection between sitting and dying isn't well understood.

"The sitting time is a little more speculative," Campbell said. "We do understand that sitting for long periods can lead to worse insulin and glucose profiles [measurements]. These worse insulin and glucose [measurements] can feed a tumor and increase risk of recurrence and death."

There is also evidence that long periods of sitting increases "oxidative stress" on the body's cells and worsens hormone balances, he added.

The new results need to be replicated before they can be considered definitive, but they are consistent with what is seen in non-cancer patients, Campbell said. Although the study suggests an association between exercise and better outcomes, it did not prove cause and effect. Many studies, however, have found this association not only for cancer, but for heart disease and other conditions.

Moreover, the benefits of exercise in maintaining normal body weight and improving strength and endurance are
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