Navigation Links
Too Much Drinking, Eating Tied to Breast Cancer Recurrence
Date:12/10/2009

Prognosis is also worse for overweight women, researchers find

THURSDAY, Dec. 10 (HealthDay News) -- Overeating and drinking even moderate amounts of alcohol may be bad news for women with breast cancer, new research suggests.

Drinking alcohol is already known to boost breast cancer risk, and a new study finds even moderate drinking may increase the odds of breast cancer recurrence. Another study confirms that overweight or obese women with breast cancer have a worse prognosis over time than thinner patients.

In the alcohol study, women who drank six grams or more of alcohol a day -- about half a drink -- had a 34 percent increased risk of recurrence compared to those who drank less, said Marilyn Kwan, staff scientist in the division of research at Kaiser Permanente, Oakland, Calif. She is scheduled to present her findings Thursday at the San Antonio Breast Cancer Symposium.

"Women who drank less than six grams a day had no increased risk of recurrence," Kwan said.

Kwan evaluated data from 1,897 early-stage breast cancer survivors who were diagnosed between 1997 and 2000. They all submitted information on alcohol consumption.

After eight years of follow-up, the researchers found 349 breast cancer recurrences and 332 deaths. For the study, they defined recurrence as including a new cancer in the opposite breast. When they took out the 32 of the 349 recurrences that occurred in the opposite breast, they found the risk slightly lower -- 31 percent, compared to 34 percent, with that finding not reaching statistical significance.

Susan Gapstur, vice president for epidemiology for the American Cancer Society, took issue with the definition of recurrence used for the study.

"With the inclusion of women who experience a new contralateral [opposite breast] cancer, the results of the study do not provide a clear picture of the risk of breast cancer recurrence associated with alcohol consumption," she said. "Therefore, more research studies are needed with larger numbers of women who experience a recurrence -- omitting those who have a new cancer in the opposite breast -- to better clarify how strong the association is."

In the obesity study, also scheduled for presentation Thursday at the symposium, Danish researchers looked at the effect of body-mass index (BMI) on the outcomes of breast cancer patients.

From a database of nearly 54,000 women, they had information on BMI for 35 percent of the women, or nearly 19,000 patients.

Breast cancer patients with a higher than normal BMI -- more than 25 -- had a higher risk of death from breast cancer than leaner patients, they found. Cancers were likely to be detected later in the heavier women, and positive treatment effects were shorter among that group of women as well.

Within the first 10 years of follow-up, which spanned 30 years for some, chemo and hormone treatments were equally effective for lean and obese women. But after a decade, the treatments were less effective in the obese women.

Gapstur, who reviewed the study, said the women diagnosed longer ago may have gotten different treatments, which could have affected the results.

"The overall take-home message of this research is that obesity contributes to a poorer overall survival, which is consistent with research published previously," she said.

As for what to do about alcohol consumption, Kwan agreed more study is needed to better define the link between alcohol consumption and recurrence risk. Meanwhile, what should breast cancer survivors do? "I would say that I think they should, given the results of our study, consider possibly minimizing their consumption of alcohol."

More information

To learn more about breast cancer, visit the American Cancer Society.



SOURCES: Marilyn L. Kwan, Ph.D., staff scientist, division of research, Kaiser Permanente, Oakland, Calif.; Susan Gapstur, Ph.D., M.P.H., vice president, epidemiology, American Cancer Society; Dec. 10, 2009, presentations, San Antonio Breast Cancer Symposium, San Antonio, Texas


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Drinking, Weight, Depression Linked in Young Women: Study
2. Research Finds Causal Link Between Ending Drinking, Depression
3. Smoking, Drinking, Cholesterol May Be Alzheimers Risk Factors
4. Heavy drinking, conduct disorder linked to high-risk sexual behavior
5. Beating Heart Differs by Gender, Age: Study
6. Lexi-Comp Focused on Improving Patient Communication in Healthcare Institutions Treating Diverse Patient Populations
7. VAI Researchers Find Long Awaited Key to Creating Drought Resistant Crops
8. Clinical trials launched for treating most aggressive brain tumor with personalized cell vaccines
9. Baxa to Sponsor ASHP Midday Symposium: Creating a Culture of Safety in Pharmacy, A Panel Discussion on Lessons Learned
10. Holiday Eating Without the Guilt -- or the Pounds
11. Novel Technology in Treating Chronic Sinus Infections Available at Baptist
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... As a ... Magna Cum Laude and his M.D from the David Geffen School of Medicine at ... returned to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars ...
(Date:6/24/2016)... Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... surgery procedures that most people are unfamiliar with. The article goes on to state ... procedures, but also many of these less common operations such as calf and cheek ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary ... Dallas that it will receive two significant new grants to support its work ... marked its 25th anniversary by recognizing patients, medical professionals and scientists for their ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain ... for a minimum wage raise to $12 an hour by 2020 and then adjusting it ... the lost value of the minimum wage, assure the wage floor does not erode again, ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & Innovative Solutions ... initiated cultivation and processing operations at its production facility, and opened its first ... is the manufacturer of a complete system of proactive air and surface purification ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Roche (SIX: RO, ROG; OTCQX: RHHBY) ... Elecsys BRAHMS PCT (procalcitonin) assay as a dedicated testing ... With this clearance, Roche is the first IVD company ... for sepsis risk assessment and management. PCT ... PCT levels in blood can aid clinicians in assessing ...
(Date:6/23/2016)... , , , WHEN: ... , , , , LOCATION: , , , Online, with ... , EXPERT PANELISTS:  , , , Frost & Sullivan,s Global Vice ... Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... industry is witnessing an exceptional era. Several new demand spaces, such ...
(Date:6/23/2016)... -- The vast majority of dialysis patients currently receive ... usually 3 times a week, with treatment times averaging ... equipment preparation and wait time.  This regimen can be ... who are elderly and frail.  Many elderly dialysis patients ... for some duration of time. Residents in ...
Breaking Medicine Technology: