Navigation Links
Too Much Acetaminophen Over Time May Damage Liver
Date:11/22/2011

TUESDAY, Nov. 22 (HealthDay News) -- Taking slightly too much of the pain reliever acetaminophen (best known by the brand name Tylenol) over time can lead to an overdose that can cause liver failure and death, according to a new study.

These "staggered overdoses" can occur when people have ongoing pain and repeatedly take a little more acetaminophen than they should, explained Dr. Kenneth Simpson, author of the study, published Nov. 22 in the British Journal of Clinical Pharmacology.

"They haven't taken the sort of single-moment, one-off massive overdoses taken by people who try to commit suicide, but over time the damage builds up, and the effect can be fatal," Simpson said in a journal news release.

He and his colleagues analyzed data from 663 patients with acetaminophen-induced liver injury who were admitted to the Royal Infirmary of Edinburgh, Scotland between 1992 and 2008. In the U.K. and elsewhere, acetaminophen is known as paracetamol.

Of those patients, 161 had suffered a staggered overdose while taking acetaminophen to relieve a variety of ailments, such as headache, toothache and abdominal and muscular pain.

Compared with people who'd taken a single overdose of acetaminophen, those with a staggered overdose were more likely to have liver and brain problems, require kidney dialysis or help with breathing, and were at greater risk of dying.

Patients with a staggered overdose may not report that they've suffered an overdose when they come to the hospital. They may just report feeling unwell. Doctors need to recognize and treat this situation quickly, Simpson said.

"Staggered overdoses or patients presenting late after an overdose need to be closely monitored and considered for the (acetaminophen) antidote, N-acetylcysteine, irrespective of the concentration of (acetaminophen) in their blood," he said in the release.

More information

The MedlinePlus Medical E
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Study links acetaminophen to lower prostate cancer risk
2. Drugmakers to End Infant Formulas of Products With Acetaminophen
3. FDA Lowers Amount of Acetaminophen Allowed in Prescription Painkillers
4. Acetaminophen use in adolescents linked to doubled risk of asthma
5. Improved method of electrical stimulation could help treat damaged nerves
6. The serotonin system in womens brains is damaged more readily by alcohol than that in mens brains
7. Stem Cells Show Promise in Healing Damaged Hearts
8. Stem cell research hopes to repair brain damage of Parkinsons disease
9. Scientists prevent cerebral palsy-like brain damage in mice
10. Flexible covering to combat water damage wins 2011 Innovation Prize
11. Protein May Help Spot Newborns With Brain Damage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/4/2015)... ... July 04, 2015 , ... Tyler Boden, Project Developer ... sales expertise from the North American Board of Certified Energy Practitioners (NABCEP®), and ... highly respected and well established national certification organization for renewable energy professionals. Designation ...
(Date:7/3/2015)... CA (PRWEB) , ... July 03, 2015 , ... ... opened for enrollment on July 2nd creating a buzz of media attention. In ... been published online by HonestyFirstReviews.com's Tiffany Hendricks. , "These days many people are ...
(Date:7/3/2015)... ... July 03, 2015 , ... ... its 2015 Annual Conference , the premiere continuing education and networking ... Orlando at SeaWorld in Orlando, Florida. Speakers include the leading rheumatology experts ...
(Date:7/3/2015)... ... 2015 , ... Renowned rhinoplasty surgeon and Symposium Chairman, Dr. ... Symposium . To be held from March 4th - 6th, the 2016 (a previous ... Galleria Dallas. , Designed to take participants from the basic training and fundamentals of ...
(Date:7/3/2015)... ... July 03, 2015 , ... B. ... has been retained to lead a national chief nursing officer recruitment ... search firms in the healthcare industry, B. E. Smith has recently placed more ...
Breaking Medicine News(10 mins):Health News:Local Solar Professional Earns Industry's Most Prestigious Certification 2Health News:Local Solar Professional Earns Industry's Most Prestigious Certification 3Health News:High Performance Academy - Review Of Brendon Burchard's New High Performance Training Program Released 2Health News:High Performance Academy - Review Of Brendon Burchard's New High Performance Training Program Released 3Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 2Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 3Health News:Dr. Rod J. Rohrich Announces the Dates for 2016 Dallas Rhinoplasty Symposium 2Health News:Dr. Rod J. Rohrich Announces the Dates for 2016 Dallas Rhinoplasty Symposium 3Health News:Jane Phillips Medical Center Retains B. E. Smith to Recruit New Chief Nursing Officer 2Health News:Jane Phillips Medical Center Retains B. E. Smith to Recruit New Chief Nursing Officer 3
... name: Trajenta) has been approved since August 2011 to ... type 2 diabetes mellitus whose elevated blood glucose levels ... an option for patients who do not tolerate or ... metformin. Moreover, linagliptin can be added if treatment with ...
... Use of statins may influence susceptibility to or the ... to a new study. While some studies ... treatment of fibrotic lung disease, others have suggested that ... by enhancing secretion of inflammasome-regulated cytokines, and numerous case ...
... News) -- Children and young adults with neurological and ... the flu and should receive flu vaccinations, say health ... February 2011. Of the 130 people living at ... neurological and neurodevelopmental conditions, 76 (58 percent) developed respiratory ...
... Jan. 5, 2012 A national clinical trial testing ... begun at Wake Forest Baptist Medical Center, the only ... will be tested in patients with newly diagnosed glioblastoma ... glioma. Wake Forest Baptist will treat a minimum of ...
... By Maureen Salamon HealthDay Reporter , WEDNESDAY, ... herpes has shown only limited effectiveness in thwarting one type ... a second type from spreading, a new study shows. , ... randomized trial on more than 8,300 women aged 18 to ...
... Low levels of vitamin D have been linked to ... with the Cooper Center Longitudinal Study. It is believed ... Low levels of vitamin D already are associated with ... neurological ailments. This new study published in ...
Cached Medicine News:Health News:Added benefit of linagliptin is not proven 2Health News:Statins may increase risk of interstitial lung abnormalities in smokers 2Health News:Novel brain tumor vaccine acts like bloodhound to locate cancer cells 2Health News:Potential Herpes Vaccine Disappoints Researchers 2Health News:Potential Herpes Vaccine Disappoints Researchers 3Health News:Low vitamin D levels linked to depression, UT Southwestern psychiatrists report 2
(Date:7/2/2015)... , July 2, 2015 Roche,s Bloodhound ... high-growth market segment in hematology testing, according to ... that Roche,s recent unveiling of its Bloodhound digital cell ... cobas m 511 hematology analyzer – is ... growth enjoyed by current leader CellaVision, but also ...
(Date:7/2/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/nlfg34/cancer ) has announced ... and by Application - Forecast to 2020" report to their ... reach $13.1 Billion in 2020 from an estimated $7.1 Billion in ... is dominated by North America , followed by ... Rest of the World (RoW). The cancer diagnostics market in ...
(Date:7/2/2015)... HILL, Conn. , July 2, 2015 ... Chief Executive Officer announced that Tamas Feitel ... Feitel joins Numotion after a highly successful 18 ... finance leadership roles driving strategy, profitability, and productivity to ... His most recent position was Chief Financial Officer for ...
Breaking Medicine Technology:Kalorama: With Bloodhound, Roche Closes in on High-Growth Hematology Segment 2Kalorama: With Bloodhound, Roche Closes in on High-Growth Hematology Segment 3Global Cancer Diagnostics Market Report 2015 - Technology, Imaging and by Applications Forecasts to 2020 for the $13 Billion Industry 2Numotion Names Tamas Feitel Chief Financial Officer 2
... YORK, Oct. 18, 2011 Reportlinker.com announces ... available in its catalogue: ... to 2015 http://www.reportlinker.com/p0535967/The-Global-Pharmaceutical-Fine-Chemicals-Market-Outlook-to-2015.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Chemical_and_Material ... This report provides a comprehensive overview ...
... 17, 2011 Berkery Noyes, the leading ... and technology industries , today released its Third Quarter ... and Healthcare Information and Technology Industry . ... first three quarters of 2011 and compares it with ...
Cached Medicine Technology:The Global Pharmaceutical Fine Chemicals Market Outlook to 2015 2The Global Pharmaceutical Fine Chemicals Market Outlook to 2015 3The Global Pharmaceutical Fine Chemicals Market Outlook to 2015 4The Global Pharmaceutical Fine Chemicals Market Outlook to 2015 5Berkery Noyes Releases Third Quarter 2011 Mergers & Acquisitions Update for the Pharma and Healthcare Information and Technology Industry 2Berkery Noyes Releases Third Quarter 2011 Mergers & Acquisitions Update for the Pharma and Healthcare Information and Technology Industry 3
VascoScrew is a low profile unipolar pacing lead with a fixed screw for permanent pacing. Due to latest technologies, VascoScrew 6/60 M is compatible to all pacemaker-cavities with the size of IS-1 (...
The VascoTip J 9/60 PU is a unipolar tined, J-preformed permanent pacing lead. Due to advanced technology, VascoTip J 9/60 PU M is compatible to all pacemaker-cavities with the size of IS-1 (3.2 mm),...
The VascoTip J 9/60 PU is a unipolar tined, J-preformed permanent pacing lead. Due to advanced technology, VascoTip J 9/60 PU M is compatible to all pacemaker-cavities with the size of IS-1 (3.2 mm),...
The Guidant Fineline EZ leads with protective capsule are bipolar endocardial and designed for permanent implantation with pulse generators for cardiac pacing....
Medicine Products: