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Too Little Vitamin D May Mean More Colds and Flu
Date:2/23/2009

lationship between vitamin D and respiratory risk, Ginde's team analyzed data from the Third National Health and Nutrition Examination Survey, collected from 1988 to 1994.

Participants were aged 12 and up -- with an average age of 38 -- and three-quarters were white. All completed nutritional and health surveys and had physical examinations. Blood samples were taken to measure levels of 25-hydroxyvitamin D, considered to be the optimal measure of vitamin D status.

The researchers found that those with less than 10 nanograms of vitamin D per milliliter of blood, considered low, were nearly 40 percent more likely to have had a respiratory infection than those with vitamin D levels of 30 ng or higher. The finding was consistent across all races and ages.

In particular, people who had a history of asthma or some form of chronic obstructive pulmonary disease (COPD) were even more likely to suffer from vitamin D deficiencies.

Asthma patients with the lowest vitamin D levels had five times the risk for respiratory infection, and vitamin D-deficient COPD patients had twice the risk.

"We still need to do the clinical trials that we already have planned to definitely say whether supplementation with vitamin D would actually reduce the risk we found," Ginde cautioned. "But I think we can say that most Americans probably do need more vitamin D for its effects on bone health, as well as for its general benefits with respect to the immune system."

Lona Sandon, an assistant professor of clinical nutrition at the University of Texas Southwestern Medical Center and a spokeswoman for the American Dietetic Association, said that evidence of a vitamin D-immune system connection seems "pretty strong."

"There does seem to be a link because, when we're not getting enough vitamin D, our immune system appears not to function at its best," she said.

Sandon noted, however, that getting enough vitamin D from food a
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