Navigation Links
Tobacco smoke and alcohol harm liver worse as combo
Date:2/3/2009

BIRMINGHAM, Ala. Exposure to second-hand smoke and alcohol significantly raises the risk of liver disease, according to researchers at the University of Alabama at Birmingham (UAB).

The finding adds to mounting evidence that tobacco smoke and alcohol are worse for health as a combination, beyond the individual exposure risks, said Shannon Bailey, Ph.D., an associate professor in the UAB Department of Environmental Health Sciences and a co-lead author on the study.

The study is published in the journal Free Radical Biology and Medicine.

"This new data is a significant finding considering the combined effect of alcohol and cigarette smoke exposures, and the implications for public health," Bailey said.

The researchers reported on mice exposed to smoky air in a laboratory enclosure and fed a liquid diet containing ethanol, the intoxicating ingredient in alcohol drinks.

Mice exposed to second-hand smoke and who drank ethanol had 110 percent more liver fibrosis proteins than mice who breathed filtered air. Additionally, the twice-exposed mice had 65 percent more liver fibrosis proteins than mice who breathed smoky air but did not drink ethanol. Fibrosis is scar-like tissue in the liver that can lead to cirrhosis.

A study from the same UAB researchers in 2007 found the combination of second-hand smoke and ethanol increased the biological signs of heart disease in mice.

Second-hand smoke kills 53,000 nonsmoking Americans every year and is a known cause of lung cancer, heart disease, low birth weight and chronic lung ailments, according to the American Cancer Society.

Excessive alcohol consumption is ranked as the third-leading cause of preventable death in the United States, according to data collected by the Centers for Disease Control and Prevention.

The new study highlights the need to further probe negative biological impacts from single or multiple risky behaviors, and the compounding effect of environmental hazards such as second-hand smoke, said Scott Ballinger, Ph.D., an associate professor in the UAB Department of Pathology and a co-lead author on the study.

In addition to measuring liver fibrosis proteins in the study mice, the researchers looked at other signs of advancing liver disease like DNA damage, unhealthy cholesterol and oxidative stress.


'/>"/>

Contact: Troy Goodman
tdgoodman@uab.edu
205-934-8938
University of Alabama at Birmingham
Source:Eurekalert

Related medicine news :

1. U.S. Senate Acts to Protect Kids, Save Lives by Increasing Federal Tobacco Taxes
2. New Super Bowl Ad Reminds Minnesotans: We All Pay the Price for Tobacco
3. North Carolina Faith Leaders Call on Sen. Burr to End Filibuster Threat of Legislation to Protect Kids From Tobacco
4. U.S. House Acts to Protect Kids, Save Lives by Increasing Federal Tobacco Taxes
5. Statewide Smoke-Free Law Must Be Comprehensive, Preserve Local Control and is Not a Substitute for a Significant Tobacco Tax Increase
6. U.S. Flunks on Tobacco Control Report Card
7. American Lung Association Report Card Flunks Federal Government and Most States for Neglecting to Prevent Tobacco Caused Illness
8. States Be Free Anti-Tobacco Campaign Lends Smokers a Helping Hand
9. American Cancer Society recognizes international tobacco control leaders
10. Study strengthens link between tobacco smoke and behavioral problems in boys with asthma
11. New Tobacco Research Finds Minnesotas Latino Population Smoking Significantly Less than General Population
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... ... ... According to an article published February 4th on mySA, robotically ... hernia repairs throughout the United States. Commenting on this article, Beverly Hills hernia repair ... has not only been expected, but it seems to be a natural result of ...
(Date:2/12/2016)... ... ... Enforcement Trends: , Back to the Future , Feb. 25, 2016 — 11:00 a.m. – ... who don’t learn from history are doomed to repeat it.” , An analysis of CDRH’s ... But that takes time. , Take a close look at the warning letters the ...
(Date:2/12/2016)... ... February 12, 2016 , ... T.E.N., ... have closed for the ISE Southeast Awards 2016. Finalists and winners of the ... ISE® Southeast Executive Forum and Awards Gala on March 15, 2016 at the ...
(Date:2/12/2016)... ... 12, 2016 , ... AssureVest Insurance Group, a locally owned insurance firm with ... will raise funds earmarked to purchase computers and software for Mrs. Harrison’s 2nd and ... is in a low-income area and has more than 60 2nd and 3rd graders ...
(Date:2/12/2016)... ... February 12, 2016 , ... Donor Network West, the organ procurement organization that ... partnership with San Ramon Regional Medical Center. Under the collaboration, the first of its ... to accommodate a more certain time frame for donor families for the recovery of ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... 12, 2016  SI-BONE, Inc., a medical device company that pioneered ... minimally invasive surgical (MIS) device indicated for fusion for certain disorders ... (NGS), the Medicare Administrative Contractor (MAC) covering the states of ... Maine , Massachusetts , Minnesota ... York , Rhode Island , ...
(Date:2/12/2016)... SAN DIEGO and SEOUL, ... -- Silicon Biosys­tems Menarini and Macrogen, Inc. today ... clinical assays and innovative procedures for precision medicine ... to combine Silicon Biosystems, DEPArray™ digital-sorting technology with ... development of tests certified under the Clinical Laboratory ...
(Date:2/12/2016)... , Feb. 12, 2016  Apellis Pharmaceuticals, ... a $47.1 million Series D preferred stock ... Management, Hillhouse Capital Group and venBio Global ... Investments, AJU IB Investment, and Epidarex Capital. The ... to further advance clinical trials in the ...
Breaking Medicine Technology: