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To what extent can environmental pollutants and alcohol affect GI health?
Date:5/31/2009

ments with NSAP from hospitals in Edmonton, Alberta. The study was replicated in more than 25,000 abdominal pain patients presenting to a hospital in downtown Montreal, Quebec. Data from Environment Canada's National Air Pollution Surveillance were used to determine the hourly levels of ozone (O3), nitrogen dioxide (NO2), sulphur dioxide (SO2), carbon monoxide (CO) and particulate matter of varying sizes (PM10 & PM2.5).

The investigators determined that nearly two-thirds of visits for NSAP were by women, and the majority of those women were ages 15 to 24. Young women were more likely to present to emergency departments in Edmonton and Montreal for NSAP on days when indicators of air pollution were elevated.

Kaplan and his co-authors speculate that young women are the most affected cohort because they are at increased risk for functional motility disorders, the most common of which is irritable bowel syndrome. He adds, however, that this research is in its early stages and that future studies will need to confirm the connection between air pollution and abdominal pain and to learn the mechanism by which air pollution may contribute to the development of abdominal pain.

Dr. Kaplan will present these data on Wednesday, June 3 at 10:30 a.m. CDT in South Hall, McCormick Place.

Alcohol Intake and Development of Symptomatic Gallstones: An Inverse Association A UK Prospective Cohort Study (Abstract #15)

Scientists have known that alcohol intake has a protective effect against the formation of gallstones, but a new study establishes for the first time the precise quantitative effect of each unit of alcohol on the development of gallstones.

Using questionnaires, investigators measured the dietary habits of 25,639 men and women and followed them for a ten-year period, during which time 267 patients developed gallstones. Participants in the study provided detailed information on
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Contact: Aimee Frank
newsroom@gastro.org
301-941-2620
American Gastroenterological Association
Source:Eurekalert

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