Navigation Links
To make old skin cells act young again, boost their surroundings, U-M scientists show
Date:12/10/2012

ANN ARBOR, Mich. As we get older, the trillions of cells in our body do too. And like us, they become less resilient and able to weather the stress of everyday life. Our skin especially tells the tale of what's happening throughout our bodies.

But recently, scientists have learned that aging cells bear only part of the blame for this downward spiral. And a new study shows that it might be possible to slow the decline of aging tissue and even make it act younger -- by focusing on the stuff that surrounds those cells.

In an independent study at the University of Michigan Medical School, skin scientists have succeeded in making the skin cells of senior citizens act like younger cells again, simply by adding more filler to the fiber-filled area around the cells.

This extracellulal matrix, or ECM, acts like the scaffold that skin cells roost in. It's made of tiny fibrils of collagen, produced by the cells (fibroblasts). Over time, as skin ages, the ECM becomes fragmented, which causes cells to lose their connections to that scaffold and the lack of support accelerates their decline further. The same thing may happen in other types of tissue.

In the new study, scientists from the U-M Department of Dermatology injected the skin of 21 volunteers in their 80s with a filler often used cosmetically to reduce facial wrinkles. The filler bolsters the ECM, filling in the spaces left by aging.

The researchers did not receive funding from the product's manufacturer, nor did they get input on the design or results from the company. Rather, they were using the product as a way to increase the mechanical forces within the volunteers' skin.

They also didn't focus on the face, where skin takes a beating over a lifetime of exposure to ultraviolet light and other insults that break down collagen. Instead, they focused on skin that had almost never seen the light of day the buttocks.

The result: over three months, t
'/>"/>

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New drug prevents spread of human prostate cancer cells
2. Tiny hitchhikers attack cancer cells
3. To prevent leukemias dreaded return, go for the stem cells
4. Scientists identify major source of cells defense against oxidative stress
5. Therapy exploits addiction of leukemia cells
6. IBN discovers human neural stem cells with tumor targeting ability
7. Leukaemia cells have a remembrance of things past
8. Small molecular bodyguards kill HPV-infected cancer cells by protecting tumor-suppressor
9. Research yields new clues to how brain cancer cells migrate and invade
10. Presence of fetal cells in women lowers risk of breast cancer but raises risk of colon cancer
11. Researchers Rejuvenate Blood-Forming Stem Cells in Mice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... than 200 experts on aggression, who research issues ranging ... the 21st World Meeting of the International Society ... Atlanta Hotel, July 15-19. , Georgia State University ... held every other year on alternating continents. , "We ... more than 20 different countries, which will help produce ...
(Date:7/10/2014)... Ticketability.com has a wide array of tickets ... tickets for San Diego are being added to the inventory. ... and the newly added September 28 show is drawing a ... Here to view the selection of discounted seats at ... become available to the general public on July 18 at ...
(Date:7/10/2014)... 2014 One week ahead of its ... announced today it will extend compensation benefits to workers ... for workers displaced as a result of factory remediation, ... have resulted in the closure of five factories for ... raising immediate safety concerns. In May, the Alliance—in a ...
(Date:7/10/2014)... 11, 2014 According to a ... by Platforms (Land, Airborne, Naval), Application (Software Defined ... by Geography (North America, Asia-Pacific, Europe, the Middle ... published by MarketsandMarkets, the market is estimated to ... to register a CAGR of 5.56% to reach ...
(Date:7/10/2014)... In his latest blog post at ... facility CEO Per Wickstrom has listed 5 ways to ... confirm an appointment, get information or sometimes even just ... being annoying is a skill that most people don’t ... to keep the dialogue moving without coming across as ...
Breaking Medicine News(10 mins):Health News:Georgia State Hosts National Conference On Aggression 2Health News:Georgia State Hosts National Conference On Aggression 3Health News:Georgia State Hosts National Conference On Aggression 4Health News:Paul McCartney Tickets for San Diego: Ticketability.com Announces Discounted Tickets for McCartney’s Tour Stop at Petco Park on September 28 2Health News:Alliance for Bangladesh Worker Safety to Double Compensation for Displaced Factory Workers; Members Vote to Extend Wage Benefits from Two to up to Four Months 2Health News:Portable Communication Systems Market Projected to Reach $39.52 Billion by 2019 - New Report by MarketsandMarkets 2Health News:Portable Communication Systems Market Projected to Reach $39.52 Billion by 2019 - New Report by MarketsandMarkets 3Health News:Portable Communication Systems Market Projected to Reach $39.52 Billion by 2019 - New Report by MarketsandMarkets 4Health News:Per Wickstrom’s Latest Blog Post Lists 5 Ways to Follow-up Without Being Annoying 2
... available everywhere in the Wadden Sea so you have to search ... where is the best place to go? Initially the food rich ... can find other animals of course and that gives rise to ... to consume the prey caught. , Takeaway meal , ...
... leading cause of adult-onset blindness, experts note , TUESDAY, Sept. ... their vision checked if they have access to health care, ... experts say. , However, minorities with diabetes or people living ... even when they know why it is important to do ...
... magnetic resonance imaging (fMRI) have found a new marker ... according to a study published in the October issue ... a potential functional, rather than structural, brain markerseparate from ... Alzheimers patients, said the studys lead author, Jeffrey R. ...
... BOTHELL, Wash., Sept. 25 Cardiac Science,Corporation ... in advanced cardiac monitoring,and defibrillation products, today ... other lay rescuers from the Pittsburgh school ... defibrillator,(AED). (Logo: http://www.newscom.com/cgi-bin/prnh/20050913/SFTU139LOGO ) ...
... for research to improve health and welfare of ... companion animals and wildlife, ... for individuals or groups to demonstrate love,for and help animals via ... about 120 animal health studies available,for sponsorship. Animal lovers are invited ...
... ... Program Oct. 1, MINNEAPOLIS and ST. PAUL, ... Minnesota,s major health plans and,ClearWay Minnesota(SM) -- is launching a new program ... patients who,want to stop smoking. The Minnesota Clinic Fax Referral Program begins,October ...
Cached Medicine News:Health News:Regular Eye Screens Spot Diabetic Vision Trouble 2Health News:Radiologists identify early brain marker of Alzheimer's disease 2Health News:Radiologists identify early brain marker of Alzheimer's disease 3Health News:Cardiac Science Applauds Mass AED Training of Pittsburgh Educators 2Health News:Cardiac Science Applauds Mass AED Training of Pittsburgh Educators 3Health News:Cardiac Science Applauds Mass AED Training of Pittsburgh Educators 4Health News:Morris Animal Foundation 2008 Sponsorship Guide Available, Details Current Animal Health Studies 2Health News:Morris Animal Foundation 2008 Sponsorship Guide Available, Details Current Animal Health Studies 3Health News:Health Organizations Join Forces Around Quit-Smoking Help 2
(Date:7/10/2014)... 10, 2014  Decision Resources Group finds that ... (ID) specialists are willing to prescribe Durata,s Dalvance ... use as OPAT, approximately two-thirds of the respondents ... their hospital inpatients. However, our findings indicate that ... initiated on OPAT following hospital discharge, and most ...
(Date:1/15/2014)... /PRNewswire-iReach/ -- ChinaMarketResearchReports.com adds "China Orthopedic Instrument Industry Report, ... (Photo: http://photos.prnewswire.com/prnh/20140115/MN46792 ) Benefiting from ... China,s orthopedic instrument industry has seen ... rising from 3.28 billion yuan in 2006 to 9.85 ...
(Date:1/15/2014)... , Jan. 15, 2014  Novation, the leading health ... several new IT value-added reseller (VAR) national contracts that ... goods and services at lower costs. These include manufacturer ... such as initiative assistance and ongoing IT consulting support. ...
Breaking Medicine Technology:Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 2Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 3Orthopedic Instrument Industry in China Markets Forecast to 2015 2Orthopedic Instrument Industry in China Markets Forecast to 2015 3New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2
Nasal Implants are used to augment the shape or reshaping of the nose....
... PTFE facial implant is an expanded ... augmentation or repair of the soft ... is available in sheets and shaped ... round facial implant strands are packaged ...
Inquire...
The MiniMed Paradigm REAL-Time System is the world's first system to integrate an insulin pump with REAL-Time continuous glucose monitoring, taking diabetes management to a level you just can't achie...
Medicine Products: