Navigation Links
To attack H1N1, other flu viruses, gold nanorods deliver potent payload
Date:5/24/2010

BUFFALO, N.Y. -- Future pandemics of seasonal flu, H1N1 and other drug-resistant viruses may be thwarted by a potent, immune-boosting payload that is effectively delivered to cells by gold nanorods, report scientists at the University at Buffalo and the U.S. Centers for Disease Control and Prevention. The work is published in the current issue of the Proceedings of the National Academy of Sciences.

"This joint research by UB and the CDC has the potential to usher in a new generation of antiviral medicines to aggressively treat a broad range of infectious diseases, from H1N1 to avian flu and perhaps Ebola, that are becoming increasingly resistant to the medicines used against them," says UB team leader Paras Prasad, PhD, executive director of the UB Institute for Lasers, Photonics and Biophotonics (ILPB) and SUNY Distinguished Professor in the departments of Chemistry, Physics, Electrical Engineering and Medicine.

The collaborative work between UB and CDC came together through the work of Krishnan Chakravarthy, an MD/PhD candidate at UB and the paper's first author. This research constitutes part of his doctoral degree work that focused on host response to influenza infection and novel drug delivery strategies.

The paper describes the single strand RNA molecule, which prompts a strong immune response against the influenza virus by ramping up the host's cellular production of interferons, proteins that inhibit viral replication.

But, like most RNA molecules, they are unstable when delivered into cells. The gold nanorods produced at UB act as an efficient vehicle to deliver into cells the powerful immune activator molecule.

"It all boils down to how we can deliver the immune activator," says Suryaprakesh Sambhara, DVM, PhD, in CDC's Influenza Division and a co-author on the paper. "The UB researchers had an excellent delivery system. Dr. Prasad and his team are well-known for their contributions to nanoparticle delivery systems."
'/>"/>

Contact: Ellen Goldbaum
goldbaum@buffalo.edu
716-645-4605
University at Buffalo
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Sexual activity declines for heart attack patients not getting doctors advice
2. Talk With Doctor Helps Heart Attack Patients Resume Sex
3. ASCO data highlight novel anti-cancer approach that exposes tumors to immune attack
4. Big Decline in Heart Attacks If All States Had Smoking Bans
5. Heart Attack Guidelines Close Racial Gaps in Hospital Care
6. Overtime Boosts Heart Attack Risk
7. COPD Flare-Up May Raise Risk of Heart Attack, Stroke
8. Scientology Official Calls for Government-Community Cooperation to Attack Drug Abuse
9. Researchers attack stem cells that cause colon cancer
10. Military develops multi-purpose green decontaminants for terrorist attack sites
11. Blood test identifies people at risk for heart attack that other tests miss
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/4/2015)... ... September 04, 2015 , ... On the heels ... doubled the size of its annual health tech innovation program. Now featuring a ... startups to compete for cash and prizes to advance their technologies toward commercialization, ...
(Date:9/4/2015)... California (PRWEB) , ... September 04, 2015 , ... The ... behalf of Tanya De La Paz. , Schmidt National Law Group, a leading ... Northern District of California against Bayer Corp., Bayer Essure, Inc., and other Bayer affiliates ...
(Date:9/4/2015)... ... September 04, 2015 , ... Georgia Insurance Advisors, a locally ... effort to provide for the family of Grace, a young local girl battling ... often leads to diastolic dysfunction – the inability to adequately move blood through ...
(Date:9/4/2015)... NC (PRWEB) , ... September 04, 2015 , ... ... Night out to benefit Core Compassion Project. Core Compassion Project is a ... specialized program to reduce the side effects of cancer treatments and recover their ...
(Date:9/4/2015)... ... September 04, 2015 , ... San Francisco ... at CitiDent. CEREC is a newer method for creating restorations through innovative imaging ... by eliminating the need for multiple appointments, CEREC produces restorations with total precision ...
Breaking Medicine News(10 mins):Health News:Insight Product Development Startup Competition on Track to Double Program Impact 2Health News:Insight Product Development Startup Competition on Track to Double Program Impact 3Health News:Schmidt National Law Group Files First Bayer Essure® Lawsuit in California 2Health News:Georgia Insurance Advisors Inaugurates Charity Drive to Assist the Family of Young Local Girl Diagnosed with an Enlarged Heart 2Health News:Georgia Insurance Advisors Inaugurates Charity Drive to Assist the Family of Young Local Girl Diagnosed with an Enlarged Heart 3Health News:Girl’s Night Out to Benefit Core Compassion Project, Located at the Beautiful, Morning Glory Farm 2Health News:San Francisco Dentist, Dr. Ben Amini, is Now Offering CEREC Technology at CitiDent 2
... Psychoanalytic,Association (APsaA) denounces the election results in California ... same-sex marriage in,the state. In keeping with its ... statement earlier this year supporting the legal,recognition of ... For the full text of the APsaA Marriage,Resolution, ...
... estrogen levels among sufferers may be the reason why, ... Women who experience migraines may actually have a 30 ... from the Fred Hutchinson Cancer Research Center in Seattle. ... this association: High levels of estrogen are associated with ...
... Foods, ... Deceptive Labeling, KELSO, Wash., Nov. 6 Salt. ... and now it,s,making waves at the government level: U.S. consumers are ingesting ... (or,up to 15 pounds per year), substantially more than the USDA recommendation,of ...
... help meet increasing demand for,pharmaceutical packaging in China, ... HON ) announced,today that it has signed ... Co., Ltd., to provide the Chinese company with,Honeywell,s ... will also provide technical services and training to ...
... cancer survival rates and should not influence decisions about how ... November issue of IJCP , the Independent Journal ... University-based researchers from Barcelona, Spain, carried out a detailed study ... "We found that there were a number of factors that ...
... Fifth International Conference on Cell Therapy for Cardiovascular ... to the evolving field of cell-based therapies for ... meeting is "Cellular and Molecular Building Blocks: Strategies ... the field will convene to present basic, core ...
Cached Medicine News:Health News:Psychoanalysts Censure California's Vote to Ban Same-Sex Marriage 2Health News:Migraine Might Lower Breast Cancer Risk 2Health News:Migraine Might Lower Breast Cancer Risk 3Health News:Spare Us the Salt! Oregonians Paying a Hefty Price for Hidden Salt 2Health News:Spare Us the Salt! Oregonians Paying a Hefty Price for Hidden Salt 3Health News:Spare Us the Salt! Oregonians Paying a Hefty Price for Hidden Salt 4Health News:Honeywell Signs Supply Agreement with Chinese Company for Aclar(R) Film 2Health News:Honeywell Signs Supply Agreement with Chinese Company for Aclar(R) Film 3Health News:Age is not a key factor in cancer survival, but clinical trials exclude older patients 2Health News:Age is not a key factor in cancer survival, but clinical trials exclude older patients 3Health News:5th Annual Global Conference on Stem Cell Therapy to be held Jan. 13-16, 2009 in NYC 2
(Date:9/4/2015)... Texas , Sept. 4, 2015  Luminex Corporation ... present at the Morgan Stanley Global Healthcare Conference to ... Grand Hyatt Hotel in New York City ... at 11:40 a.m. Eastern time on Friday, September 18, ... accessed at Luminex Corporation,s website at http://www.luminexcorp.com . ...
(Date:9/4/2015)... 4, 2015 According to a ... Plateletpheresis, Erythrocytapheresis, Leukapheresis, and Photopheresis) by Procedure (Therapeutic Apheresis, ... - Global Forecast to 2020", published by MarketsandMarkets, the ... Billion by 2020, growing at a CAGR of 11.2% ... Browse 139 Tables and 45 F ...
(Date:9/4/2015)... Oramed Pharmaceuticals Inc. (NASDAQ: ... focused on the development of oral drug delivery systems, ... upcoming Rodman & Renshaw 17 th Annual Global ... New York City .  Dr. Michael ... overview on September 9, 2015. Presentation ...
Breaking Medicine Technology:Luminex Corporation To Present At The Morgan Stanley Global Healthcare Conference 2Apheresis Market Worth 2.5 Billion USD by 2020 2Apheresis Market Worth 2.5 Billion USD by 2020 3Apheresis Market Worth 2.5 Billion USD by 2020 4Apheresis Market Worth 2.5 Billion USD by 2020 5Oramed to Present at the Rodman & Renshaw Global Investment Conference 2Oramed to Present at the Rodman & Renshaw Global Investment Conference 3
... 2011 Par Pharmaceutical Companies, Inc. (NYSE: PRX ... EST on Friday, January 6, 2012 at the Millennium Hotel, ... Executive Officer, Patrick G. LePore, and other members of the ... growth strategy, current products and pipelines, and business outlook to ...
... Calif., Dec. 5, 2011  Beyond Lucid Technologies, Inc., ... disaster management, and First Response industries, today announced ... the mHealth Summit, and the publication of a ... connect ambulances with hospitals via telemedicine. ...
Cached Medicine Technology:Beyond Lucid Technologies Advances Telemedicine for EMS Providers 2Beyond Lucid Technologies Advances Telemedicine for EMS Providers 3
... spot technology the Technolas 217z Zyoptix System, ... vision correction, allows surgeons in the United ... Diopters and astigmatism up to -3.00 Diopters. ... a 2mm and 1mm truncated Gaussian beam, ...
... IGF-I kit is a two-site ELISA for ... (IGF-I) in serum or plasma. The assay ... in microtiter wells and a high affinity ... simple sample pre-treatment replaces acid/ethanol extraction to ...
... The AutoDELFIA C-peptide kit is for the ... heparin plasma using the AutoDELFIA Automatic Immunoassay ... the residual -cell function in patients treated ... and type 2 diabetes, and various other ...
Measles IgG ELISA test system is designed for the qualitative detection of IgG antibodies to Measles (Rubeola) virus in human serum, and is for in vitro diagnostic use....
Medicine Products: