Navigation Links
Titanium Joint Debris May Trigger Painful Inflammation
Date:11/28/2011

MONDAY, Nov. 28 (HealthDay News) -- Patients who receive artificial joints made with titanium may develop painful inflammation that could destroy bone and loosen the new joint, according to a new study of mice published by the Journal of Immunology.

Contrary to previous studies that blamed bacteria for the inflammation, researchers at the University of Medicine and Dentistry of New Jersey reported that tiny titanium particles that flake off the artificial joints through normal wear and tear may be the cause of the inflammation.

The type of inflammatory response triggered, known as a Th2 response, is more commonly associated with allergic responses and parasitic worm infections, the researchers said in a university news release. The titanium particles, which were seen an invading parasites or allergens, resulted in the generation of immune cells called "alternatively activated macrophages" in the mice.

The release noted although the potential effects of inflammation in the joint are not entirely clear, there is increasing evidence that alternatively activated macrophages contribute to bone destruction in patients who receive prostheses and in those with certain forms of arthritis.

More information

The American Society of Orthopaedic Surgeons provides more information on joint replacement.

-- Mary Elizabeth Dallas

SOURCE: University of Medicine and Dentistry of New Jersey, news release, Nov. 21, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Study helps eliminate causes for joint pain linked to commonly used breast cancer drugs
2. Studies Suggest Link Between Smog, Joint Disease
3. A new definition for periprosthetic joint infection
4. Race Tied to Risk for Arthritis in Large Joints
5. Joint preservation in osteoarthritis
6. More African-Americans burdened by osteoarthritis in multiple large joints
7. FDA and NIH announce joint study on tobacco use and risk perceptions
8. Radiation boost for artificial joints
9. Lawson scientist presents joint pain treatment 2.0
10. Vitamin D relieves joint, muscle pain for breast cancer patients
11. Joint winners announced in Research4life global case study competition
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Titanium Joint Debris May Trigger Painful Inflammation
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & Innovative Solutions ... initiated cultivation and processing operations at its production facility, and opened its first ... is the manufacturer of a complete system of proactive air and surface purification ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) sponsors ... on June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, ... to helping service members that have been wounded in battle and their families. Venture ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that ... PCT (procalcitonin) assay as a dedicated testing solution for ... clearance, Roche is the first IVD company in the ... risk assessment and management. PCT is a ... in blood can aid clinicians in assessing the risk ...
(Date:6/23/2016)... 23, 2016 Capricor Therapeutics, ... a biotechnology company focused on the discovery, development ... patient enrollment in its ongoing randomized HOPE-Duchenne clinical ... 50% of its 24-patient target. Capricor expects the ... quarter of 2016, and to report top line ...
(Date:6/23/2016)... Pa. , June 23, 2016 Bracket ... will launch its next generation clinical outcomes platform, Bracket eCOA ... Meeting held on June 26 – 30, 2016 in ... the first electronic Clinical Outcome Assessment product of its kind ... Booth #715. Bracket eCOA 6.0 is a flexible ...
Breaking Medicine Technology: