Navigation Links
Tissue engineering methods earn funding to heal little hearts
Date:2/18/2011

HOUSTON (Feb. 18, 2011) -Texas Children's Hospital in Houston announces that a researcher in its Pediatric Cardiac Bioengineering Laboratory has earned a National Science Foundation Early Career Development (CAREER) Award for his work in studying the causes of congenital heart disease, heart defects, and the development of tissue engineering therapies using stem cells derived from human amniotic fluid. The award comes with new funding of $450,000 to be spread over a five-year period.

Jeffrey Jacot, Ph.D, director of the Pediatric Cardiac Bioengineering Laboratory at the Congenital Heart Surgery Service at Texas Children's Hospital and an assistant professor of bioengineering at Rice University, submitted work based on two years of previously published studies on the effects of substrate stiffness on maturing heart cells, the mechanical environment of cardiovascular tissues, and the development of heart tissue grown from stem cells taken from the amniotic fluid of patients' mothers. His work with cardiac tissue stems from a 2009 grant from the Virginia and L.E. Simmons Family Foundation Collaborative Research Fund, which promotes research among Texas Medical Center scientists, engineers and doctors who might not otherwise work together.

"I am pleased to be part of the groundbreaking congenital heart research at Texas Children's Hospital," said Dr. Jacot. "We hope this work will lead to the development of living heart tissue that might work to 'patch' or reconstruct hearts with congenital defects."

As a principal investigator on several projects, Jacot works alongside surgeons and radiologists at Texas Children's Hospital and with cardiovascular research laboratories at Baylor College of Medicine (BCM) to establish a therapeutically feasible stem cell source and understand how to control growth of new cardiac tissue.

"Dr. Jacot is a talented and highly inventive young member of the biomedical engineering community whose detailed analysis and rationally designed experiments bring a unique approach to the study and treatment of congenital heart disease," said Charles D. Fraser Jr., M.D., surgeon-in-chief and chief of congenital heart surgery at Texas Children's Hospital and professor of surgery at BCM. "Because the regenerative cardiac therapies developed in his lab are grown from amniotic fluid-derived stem cells, they are genetically identical to the child and have potential to grow with the patient with minimal immune response."

Jacot's CAREER Award also includes an interactive exhibition and outreach program for elementary, middle and high school students to be developed in cooperation with the John P. McGovern Museum of Health and Medical Science (MMHM) in Houston. The educational component, which is intended to inspire and help guide the next generation of scientists and engineers, includes field trips and teacher workshops, as well as lectures and problem-based curriculum in systems physiology at Rice.


'/>"/>

Contact: Carol Wittman
cmwittma@texaschildrens.org
832-824-2040
Texas Children's Hospital
Source:Eurekalert

Related medicine news :

1. New study suggests stem cells sabotage their own DNA to produce new tissues
2. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
3. Step Up to Speak Up Events Use Spoken Word and African-American Greek Tradition of Stepping to Raise Awareness for Organ and Tissue Donation
4. CSMG Technologies, Inc. Engages New Team to Manage Live Tissue Connect, Inc.
5. Paired drugs kill precancerous colon polyps, spare normal tissue
6. Tissue engineers create a new way to assemble artificial tissues
7. Ultrasound could boost tissue implant success
8. Color-coded tracking method helps scientists analyze outcomes of newly transplanted tissue
9. Molecular Signatures in Post-Mortem Brain Tissue of Younger Individuals at High Risk for Alzheimer's Disease
10. Scholar calls for a new legal, ethical framework for research with human tissue specimens
11. New method of tissue banking makes gene analysis more practical for lung cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/9/2016)... ... February 09, 2016 , ... ... software, in partnership with Snowfall4pod Digital, creators of the gContentManager & Distribution ... content management, global distribution and print-on-demand network. , AVALANCHE allows enterprise customers ...
(Date:2/9/2016)... ... February 10, 2016 , ... The Journal of ... to “level the playing field .” , As corresponding author Dr John F. Peppin ... to categorize and diagnose our chronic pain patients. ‘Chronic cancer pain’ and ‘chronic ...
(Date:2/9/2016)... , ... February 09, 2016 , ... ... The guide will ensure lab personnel have a basic understanding of the techniques ... measurement protocols. Enhanced understanding will help them reduce waste and rework to create ...
(Date:2/9/2016)... ... February 09, 2016 , ... Sir Grout, the leading ... proud to announce that many of their franchises have received the Super Service ... surface restoration franchises received customer recognition through positive reviews and testimonials, as well ...
(Date:2/8/2016)... ... ... CURE Media Group , the nation’s leading digital and print media enterprise ... , which will annually honor individuals making heroic contributions in the field of multiple ... Awards nomination process is officially open through February 17 for patients, caregivers and ...
Breaking Medicine News(10 mins):
(Date:2/9/2016)... , Feb. 9, 2016 The new report "Global ... Acuity Business Research & Consulting group reveals that the ... with a share of 38.9% in 2014 that translated into revenues ... , Europe , Asia-Pacific , ... and Africa . The global anti-bacterial market is ...
(Date:2/8/2016)... Cardiac Assist Devices - ... GlobalData,s Medical Devices sector report, " Cardiac Assist ... provides an overview of Cardiac Assist Devices currently ... information on the pipeline products with comparative analysis ... The report reviews major players involved in the ...
(Date:2/8/2016)... Cardiovascular Surgery Devices - Medical Devices ... Devices sector report, "Cardiovascular Surgery Devices - Medical ... Cardiovascular Surgery Devices currently in pipeline stage. ... report provides comprehensive information on the pipeline products ... stages of development. The report reviews major players ...
Breaking Medicine Technology: