Navigation Links
Tissue analyses indicate survival benefits for some lung cancer patients

Taking small tissue samples from patients with lung cancer and examining them under a microscope (a procedure called histology) is now being utilized to better tailor the chemotherapy treatments to improve survival in some patients with non-small cell lung cancer, according to a study presented at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology, cosponsored by ASTRO, ASCO, IASLC and the University of Chicago.

Cancer researchers have begun to believe in a tailored approach to chemotherapeutic intervention based on the histology or tissue type in the treatment of non-small cell lung cancer. To prove this hypothesis, cancer researchers from Pennsylvania State Hershey Cancer Institute in Hershey, Pa., Medical University of Vienna in Vienna, Austria, University of Torino in Orbassano, Italy, and Eli Lilly and Company of Indianapolis, Ind., considered two large studies, each of which compared pemetrexed-based (chemotherapy-based) treatment to a control treatment. They analyzed each of these studies for the presence of a treatment-by-histology interaction. A treatment-by-histology interaction exists if the relative benefit of the pemetrexed-based treatment (compared to the control treatment) depends on histology. The analyses show that a strong treatment-by-histology interaction exists for both studies, indicating that pemetrexed-based treatment is more effective in patients with non-squamous histology as compared to squamous histology.

"Nonsquamous histology is predictive of improved efficacy of the chemotherapy agent pemetrexed in patients with non-small cell lung cancer," said Chandra Belani, M.D., a lung cancer specialist from Pennsylvania State Hershey Cancer Institute. "This study is building the body of evidence showing that examining tissue types can help doctors find the most effective treatments for patients with lung cancer and other diseases."


Contact: Beth Bukata
American Society for Therapeutic Radiology and Oncology

Page: 1

Related medicine news :

1. Stem cells with potential to regenerate injured liver tissue identified by Penn researchers
2. Global Growth Factors (Blood and Tissue) Market to Reach $52.1 Billion by 2012, According to New Report by Global Industry Analysts
3. New advancements in the use of adult, embryonic stem cells for tissue regeneration
4. Melanin production discovered in fat tissue
5. Pathwork Tissue of Origin Test Shows Potential to Aid in the Diagnosis of Cancer of Unknown Primary
6. AxoGen Awarded Accreditation from American Association of Tissue Banks : Decision Affirms AxoGen's Commitment to Safety and Ethicality in the Development and Distribution of AVANCE Nerve Graft for Treatment of Peripheral Nerve Injuries
7. MTF, Largest Tissue Bank, Donates Skin to Mexican Burn Victim
8. MRI Detects Soft Tissue Damage Affecting Kids Hearing
9. Drug Given 24 Hours After Stroke Helps Repair Brain Tissue
10. New Research Shows Cadaver Tissue Fails Nearly a Quarter of the Time in Young, Athletic ACL Reconstruction Patients
11. ACL Reconstruction With Cadaver Tissue Risky in Younger Patients
Post Your Comments:
(Date:11/25/2015)... ... November 25, 2015 , ... Lakeview Health, a ... to celebrate their sobriety and show through pictures what a positive difference it ... this Thanksgiving with the hashtag #FacesOfGratitude on their Facebook, Twitter, and Instagram accounts. ...
(Date:11/25/2015)... ... November 25, 2015 , ... Wimbledon ... programs, launches new Wimbledon Athletics Facebook page to educate the public, ... unsuspected cardiac abnormalities. About 2,000 people under the age of 25 die from ...
(Date:11/25/2015)... , ... November 25, 2015 , ... Smiles by ... TMJ Disorder, Bruxism, and moderate facial wrinkling. While many patients are aware of the ... the great success Botox® delivers to those suffering with discomfort, soreness, and pain as ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... of music, friendships, and learning in its 65th Anniversary Brillianteen Revue, scheduled for ... , For 65 years, Brillianteen has been a treasured tradition for ...
(Date:11/25/2015)... ... November 25, 2015 , ... Today, Mothers Against ... nation’s roadways has dropped below 10,000 for the first time since 2011. In 2014, ... , According to data released by the National Highway Traffic Safety Administration (NHTSA), 32,675 ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)...  Amgen (NASDAQ: AMGN ) today announced the ... the United States (U.S.) Food and ... to Humira ® (adalimumab). Amgen believes this submission ... FDA and represents Amgen,s first BLA submission using the ... M.D., executive vice president of Research and Development at ...
(Date:11/25/2015)... 25, 2015  Linden Care, LLC, a retail specialty ... for patients suffering from chronic pain, said today that ... Restraining Order (TRO) enjoining Express Scripts from unilaterally terminating ... --> --> The company ... legal options. --> --> ...
(Date:11/25/2015)... -- On Tuesday, November 24, 2015, the jury ... Medical Technology, Inc. for product liability and misrepresentation ... device, awarded $11 million in favor of Plaintiff ... three days of deliberations, the jury found that ... and unreasonably dangerous, and that Wright Medical made ...
Breaking Medicine Technology: