Navigation Links
Tips from the journals of the American Society for Microbiology
Date:8/15/2011

nes that are being expressed. Glazer showed that the silencing of BRCA1 is accompanied by a change in the histones, called methylation, which is frequently seen when gene expression is reduced.

"We then found that one particular enzyme, called lysine demethylase [LSD1] is manipulating the methylations," says Glazer. Finding a way to block that enzyme could lead to reactivating BRCA1, he says, noting that this might be done by finding a small molecule that inhibits that enzyme's activity. Such a drug might reactivate other tumor suppressors as well, he says.

Glazer thinks that cell stress in general caused by hormones or environmental toxins may lead to silencing BRCA1, and he plans to investigate that hypothesis.

(Y. Lu, A. Chu, M.S. Turker, and P.M. Glazer, 2011. Hypoxia-induced epigenetic regulation and silencing of the BRCA1 promotor. Mol. Cell. Biol. 31:3339-3350.)


How Excess Alcohol Depresses Immune Function

Alcoholism suppresses the immune system, resulting in a high risk of serious, and even life-threatening infections. A new study shows that this effect stems largely from alcohol's toxicity to immune system cells called dendritic cells. These cells play a critical role in immune function, responding to danger signals by searching for unfamiliar antigens within the body that would be coming from invading microbes, and presenting such antigens to T cells, thus activating them to seek and destroy cells containing these antigens. The research is published in the July 2011 issue of the journal Clinical and Vaccine Immunology.

Earlier studies in mice had shown that excessive drinking of alcohol impaired T cell function, and subsequently that this impairment could be reversed by exposure to dendritic cells (so named for their shape) from non-alcoholic mice, and that poor function in CD4 and CD8 T cells could be improved through exposure to cytokines produced by non-alcoholic dendriti
'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Page: 1 2 3 4 5 6

Related medicine news :

1. Over 40 new titles added to Wiley-Blackwells journals program in 2011
2. New study: Serious gaps in medical journals disclosure of physician relationships with industry
3. CONSORT 2010: Leading journals publish new guidelines to improve trial reports
4. Bad Economic News Taking Toll on Americans Emotions
5. More American Kids Eating Fast Food
6. Americans Use of Antidepressants On the Rise: Study
7. Americans No Longer Outliving Europeans: Study
8. Effects of tobacco use among rural African American young adult males
9. Painful Gout Afflicting More Americans: Study
10. Americans Show Rising Support for Abortion Rights: Poll
11. New data-based strategies and treatment models can improve diabetes care for older African-Americans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 22, 2015 The Incredible Bulk is a ... to increase lean muscle by up to 30lbs in less ... attention of HealthyandFitZone.com’s Stan Stevenson, prompting an investigative review. , ... a step-by-step, scientific diet formula that allows the body to ...
(Date:1/22/2015)... the premier women’s dress supplier, has recently released its ... of AngelWeddingDress.com to find more details. , Many ... a bridal party. AngelWeddingDress offers a variety of gorgeous ... wedding dresses are specially designed for 2015. , AngelWeddingDress ...
(Date:1/22/2015)... January 22, 2015 A new white ... experience and person-centeredness in the long-term care environment as ... across the continuum. The paper, “The Power of Person-Centeredness ... perspectives and practices of the patient, resident and family ...
(Date:1/22/2015)... 20 years, Dr. David Cruz of Cruz Chiropractic Care ... about every type of injury that can result from car accidents ... years, the team at Doctors on Liens has been ... With the combined breadth of experience between the two, ...
(Date:1/22/2015)... January 22, 2015 A study ... Medicine flagship journal Medicine & Science in Sports ... exercise may help reduce gastrointestinal (GI) problems associated ... , Participants in the double-blind, placebo-controlled study took ...
Breaking Medicine News(10 mins):Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3
... Dec. 3 The four million Americans who,suffer from ... today with,the announcement of an unprecedented research program to ... treatment of CFS. The,announcement was made by the CFIDS ... Accelerate CFS Research Initiative. , ...
... have identified a molecular cause behind the ravages of ... how a natural process for fighting cancer in younger ... senescence, the process by which biological cells stop dividing ... was shown to trigger the secretion of proteins that ...
... premiums have slowed to less than half the growth rate ... waste in the health care system continue to fuel underlying ... , , Prepared by ... "The Factors Fueling Rising Healthcare Costs 2008" examines the causes ...
... replace mammography for screening yet, experts say, , , WEDNESDAY, ... techniques will help doctors diagnose and stage breast cancer, ... detection of breast cancer. , Both tests -- breast-specific ... rely on the use of radiotracers to detect cancer ...
... have adopted,New Jersey,s unique and successful "Mayors Wellness Campaign" (MWC) ... Times Free Press on Monday,reported that the cities of Athens ... the New Jersey program through their health plan.,(The article can ... The Mayors Wellness Campaign is an ...
... treatment seems to improve cognitive functioning in patients with ... according to the results of a randomized clinical trial ... study led by Sonia Ancoli-Israel, Ph.D., professor of ... and one of the nation,s preeminent experts in the ...
Cached Medicine News:Health News:New Research Will Benefit Four Million Americans Suffering from Chronic Fatigue Syndrome 2Health News:New Research Will Benefit Four Million Americans Suffering from Chronic Fatigue Syndrome 3Health News:New Research Will Benefit Four Million Americans Suffering from Chronic Fatigue Syndrome 4Health News:Cellular senescence a double-edged sword 2Health News:Cellular senescence a double-edged sword 3Health News:Cellular senescence a double-edged sword 4Health News:Cellular senescence a double-edged sword 5Health News:New Report Shows Slower Premium Growth, But Increasing Pressure to Address Waste in Health Care System 2Health News:New Report Shows Slower Premium Growth, But Increasing Pressure to Address Waste in Health Care System 3Health News:Latest Breast Imaging Techniques Offer New Views 2Health News:Latest Breast Imaging Techniques Offer New Views 3Health News:New Jersey's 'Mayors Wellness Campaign' Goes National! 2Health News:Treating sleep apnea in Alzheimer's patients helps cognition 2Health News:Treating sleep apnea in Alzheimer's patients helps cognition 3
(Date:1/22/2015)... 22, 2015 Increasing sophistication among enterprise buyers of ... purchasing in 2015, says Moravia CMO, ... study by market research firm Common Sense Advisory, 15 ... their translation and localization needs. "From a language industry ...
(Date:1/22/2015)... 22, 2015 Research and Markets ( ... "Microbiology Testing/Clinical Microbiology Market by Product, Clinical ... 2019" report to their offering. ... techniques for the detection of infectious diseases. The ...
(Date:1/22/2015)... , Jan. 22, 2015 The Parenteral Drug Association (PDA) ... SM : Enabling Pharmaceutical Manufacturing,s Future. ... following goals: , Highlight the ongoing focus PDA ... build practical solutions by filling known gaps in current manufacturing ...
Breaking Medicine Technology:Moravia Sees Single-Sourcing as Key Localization Trend in 2015 2Global Microbiology Testing/Clinical Microbiology (Instrument, Analyzer, Incubator, Kit, Microscope, Molecular Diagnostics) Market - Forecast to 2019 2Global Microbiology Testing/Clinical Microbiology (Instrument, Analyzer, Incubator, Kit, Microscope, Molecular Diagnostics) Market - Forecast to 2019 3PDA Launches Manufacturing Science Program(SM) 2PDA Launches Manufacturing Science Program(SM) 3
... The Cypress quick test is a rapid ... antibodies to Trypanosoma cruzi. It can ... plasma. The method employs a unique combination ... is conjugated on dye particles, and antigens ...
Silicone ICD lead...
The Livewire steerable electrophysiology catheter is uniquely designed with an ergonomic handle and patented steering mechanism to provide smooth, precise catheter tip movement, even during lengthy e...
... Glaucoma Treatment System will provide ... glaucoma treatments through the use ... (GMS) and DeepLight 790 Titanium ... the eye's natural pressure differential ...
Medicine Products: