Navigation Links
Tiny radioactive spheres effectively treat cancer that has spread to the liver
Date:10/29/2007

JACKSONVILLE, Fla. − Placing tiny radioactive spheres directly into the liver through its blood supply halted growth of tumors that had spread to the organ in 71 percent of patients tested in a small clinical trial, researchers from Mayo Clinic Jacksonville report.

They say that the technique appears to offer a treatment option for patients who develop multiple tumors in their liver from cancer metastasis.

Most of these patients dont have other effective treatment options, because surgery is not possible if there are multiple tumors in their liver, says the studys lead investigator, Laura Vallow, M.D. But with this radiotherapy, no new tumors developed in patients who responded and we find this to be very encouraging.

Vallow presented results of the study at the annual meeting of the American Society for Therapeutic Radiation and Oncology (ASTRO).

She says her report is one of the first to sum up an initial clinical experience with the therapy, known as SIR-Spheres microspheres, which was approved for use by the federal Food and Drug Administration in 2002. We are trying to determine the clinical situations in which it is best to use these microspheres, Vallow says.

The therapy uses millions of tiny polymer beads − each one of which is about one-third the diameter of a human hair − which contain the radioactive element yttrium-90. An interventional radiologist uses a catheter to infuse the microspheres directly into the hepatic artery, which supplies all the blood to the liver. There the beads deliver radiation directly to tumors for about 11 days.

In this study, data from 20 patient procedures using microspheres at Mayo Clinic Jacksonville were analyzed. The entire liver was treated in 75 percent of the cases, and in the remaining 25 percent, either the left or right lobe of the liver was selectively targeted. Four weeks after treatment, researchers used CT scans to assess response of tumors, and found that in 71 percent, tumors decreased in size. The tumors were smaller or less active with less contrast uptake on follow-up CT scans, Vallow says.

The majority of patients had minimal side effects from the treatment, she says. Cancer progressed in two patients and they died within three months. But for the patients who responded, by the end of a 10-month follow-up period, no new tumors were detected, Vallow says. Liver function tests in the responding patients have become normal or have stabilized.

The researchers say the treatment works best in patients that have good blood flow to their tumors. Further evaluation with longer follow-up will help clarify the benefit of this novel treatment, Vallow says.


'/>"/>
Contact: Kevin Punsky
punsky.kevin@mayo.edu
904-953-2299
Mayo Clinic
Source:Eurekalert

Related medicine news :

1. Radioactive Seeds used in Prostate Cancer treatment can migrate with the body
2. Bacteria Commonly Seen In Radioactive Waste, Hot Springs Found Inside Humans
3. Brain Cancer Could be Safely Treated with Radioactive Scorpion Venom
4. Chornobyl Incident Proved Increased Risk of Thyroid Cancer from Radioactive Iodine
5. Adult COPD or asthma could be effectively treated with Xopenex
6. CPR! How Effectively is it being done ?
7. Using Cholesterol Lowering Drugs Effectively
8. Older Breast Cancer Patients Can Be Effectively Treated With Chemotherapy
9. Fungal Infections Effectively Controlled By Light Therapy
10. Elderly People Needs To Tackle The Heat Effectively
11. Treating Autism More Effectively
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... Dallas, Texas (PRWEB) , ... February 08, 2016 , ... The Valentine’s Season is famous ... family members and significant others that they are loved. This year, for more than ... much they cost - just won't be enough to remind them of the lives they’ve ...
(Date:2/8/2016)... Hilton Head Island, SC (PRWEB) , ... February 08, 2016 , ... ... Head and surrounding areas with a vital new community enrichment program, has teamed up ... to local women and children suffering from intimate abuse. To support all those victimized ...
(Date:2/8/2016)... ... ... Remember the old saying “rub some dirt on it”? Perhaps you should try using ... the health benefits of integrating clay into a daily diet are numerous, as clay ... speaker, Perry A~ has since dedicated her life to learning about the benefits of ...
(Date:2/8/2016)... Gaithersburg, MD (PRWEB) , ... February 08, 2016 ... ... (AHCC) is excited to share this important news! AHCC and the Home Health ... (AHA) Coding Clinic, CMS' designee for official ICD coding guidance and clarifications, to ...
(Date:2/8/2016)... ... February 08, 2016 , ... According to research ... U.S. require dental technicians to be certified or obtain continuing education. To increase ... the “What’s In Your Mouth?” campaign to inform dentists and patients about the ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... , Feb. 8, 2016 ... addition of the "Label-Free Detection Market ... to 2020" report to their offering. ... the addition of the "Label-Free Detection ... Forecasts to 2020" report to their ...
(Date:2/8/2016)... Therapeutics, Inc. announced today that the United States Patent and ... the use of NephroFlow to treat acute kidney injury (AKI). ... "We are pleased to secure our rights to such a ... HemaFlo,s founder, said, "We are pleased to secure our rights ... Dale Peterson , PhD, HemaFlo,s founder, said, "We are pleased ...
(Date:2/8/2016)... , Feb. 8, 2016  Dynatronics Corporation (NASDAQ: ... advanced-technology medical devices and rehabilitation equipment for the ... the Denver Broncos, football team for winning the ... Jr. , Chairman and Chief Executive Officer.  "The ... we look forward to enhancing their athletic achievements ...
Breaking Medicine Technology: