Navigation Links
Tiny levels of carbon monoxide damage fetal brain
Date:6/25/2009

A UCLA study has discovered that chronic exposure during pregnancy to miniscule levels of carbon monoxide damages the cells of the fetal brain, resulting in permanent impairment. The journal BMC (BioMed Central) Neuroscience published the findings June 22 in its online edition.

"We expected the placenta to protect fetuses from the mother's exposure to tiny amounts of carbon monoxide," said John Edmond, professor emeritus of biological chemistry at the David Geffen School of Medicine at UCLA. "But we found that not to be the case."

The researchers exposed pregnant rats to 25 parts per million carbon monoxide in the air, an exposure level established as safe by Cal/OSHA, California's division of occupational health and safety.

Dr. Ivan Lopez, UCLA associate professor of head and neck surgery, tested the rats' litters 20 days after birth. Rats born to animals who had inhaled the gas suffered chronic oxidative stress, a harmful condition caused by an excess of harmful free radicals or insufficient antioxidants.

"Oxidative stress damaged the baby rats' brain cells, leading to a drop in proteins essential for proper function," said Lopez. "Oxidative stress is a risk factor linked to many disorders, including autism, cancer, Alzheimer's, Parkinson's, Lou Gehrig's disease, multiple sclerosis and cardiovascular disease. We know that it exacerbates disease."

"We believe that the minute levels of carbon monoxide in the mother rats' environment made their offspring more vulnerable to illness," added Edmond. "Our findings highlight the need for policy makers to re-examine the regulation of carbon monoxide."

Tobacco smoke, gas heaters, stoves and ovens all emit carbon monoxide, which can rise to high concentrations in well-insulated homes. Infants and children are particularly vulnerable to carbon monoxide exposure because they spend a great deal of time in the home.

No policies exist to regulate the gas in the home. Most commercial home monitors sound an alarm only hours after concentrations reaches 70 parts per million--nearly three times the 25 parts per million limit set by Cal/OSHA.


'/>"/>

Contact: Elaine Schmidt
eschmidt@mednet.ucla.edu
310-794-2272
University of California - Los Angeles
Source:Eurekalert

Related medicine news :

1. After Major Ruling on Unsafe Lead Levels in Paint, Experts Reveal How You Can Ensure Your Kids Are Safe
2. Blood-Sugar Spikes Send Testosterone Levels Down
3. New Study Shows Coaching to Patient Activation Levels Improves Disease Management Outcomes
4. New Study Shows Coaching to Patient Activation Levels Improves Disease Management Outcomes
5. Automated Artificial Pancreas Controls Blood Glucose Levels in Diabetes Patients for First Time
6. Prospective Evaluation Finds High Levels of Satisfaction with ConvaTec Moldable Skin Barrier
7. Low Vitamin D Levels May Initiate Cancer Development
8. Long-term study shows low oxygen levels in prostate tumors can predict recurrence
9. Study finds iron levels not predictive of survival for form of blood cancer
10. Photo: Levemir(R) Once-Daily Substantially Lowered Average Blood Sugar Levels of Patients with Type 2 Diabetes in TITRATE(R) Study
11. Parents of internationally adopted children advised to verify childrens immunization levels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) ... a collection of specialty vendors and unique items from across the nation, this holiday-themed ... and wellness services offered by the VNA. The boutique will be open Saturday, ...
(Date:10/13/2017)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has released ... understood books in the Holy Scriptures, Revelation. The Book of Revelation paints a picture ... Many have tossed it off as mere rubbish, but Yisrayl Hawkins says that is ...
(Date:10/13/2017)... , ... October 13, 2017 , ... “The Journey: From ... every danger possible to save lost souls in the Philippines. “The Journey: From the ... is a dedicated teacher of the Bible. She has taught all ages and currently ...
(Date:10/12/2017)... CA (PRWEB) , ... October 12, 2017 , ... ... Cheng, are now treating sleep apnea using cutting-edge Oventus O2Vent technology. ... a serious sleep disorder characterized by frequent cessation in breathing. Oral appliances can ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ), one ... an innovative new design of the shoulder pad. The shoulder pad provides optimal ... controlling your pain while using cold therapy. By utilizing ice and water that is ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)...   Divoti USA will engrave and process ... of the latest FDA requirements, which stipulates new criteria regarding medical ... need of Medical ID jewelry such as Medical ID Bracelets, can ... in terms of the new FDA requirements . ... Divoti offers this dark mark fiber laser ...
(Date:10/11/2017)... 2017  Caris Life Sciences ® , a leading ... of precision medicine, today announced that St. Jude Medical ... Alliance™ (POA) as its 17 th member. Through ... Crosson Cancer Institute will help develop standards of care ... profiling, making cancer treatment more precise and effective. ...
(Date:10/10/2017)... Calif. , Oct. 10, 2017  NDS received FDA 510(k) ... — a medical-grade battery-powered display stand specifically designed for endoscopy environments. ... transform technology into a clinical solution to support the improvement of ... Innovative Design ... Mobile Wireless Solution ...
Breaking Medicine Technology: