Navigation Links
Tiny gems take big step toward battling cancer
Date:3/9/2011

chemotherapy drug doxorubicin to them using a scalable synthesis process, which enhances sustained drug release.

Ho and his colleagues studied mouse models with liver and breast cancers. In these resistant cancers, drugs are able to get inside the tumors but are kicked right back out because of an innate response in the liver and breast to expel these drugs.

They treated one group of animals with the doxorubicin-nanodiamond complexes and another group with the drug alone. In those treated with the nanodiamond complexes, the chemotherapeutic remained in circulation longer -- up to 10 times longer -- than those treated with the drug alone. In addition, the drug itself was retained within both types of tumors for a significantly longer period of time. Such a high retention rate means a smaller amount of the very toxic drug would need to be administered, thus reducing side effects.

The researchers also found that the drug-nanodiamond complexes had no negative effect on the white blood cell count. This is especially important for cancer treatment: if the white blood cell count drops below a certain level, treatment is stopped due to the risk of major complications.

"Nanodiamonds have excellent biocompatibility, and the process of formulating nanodiamond-drug complexes is very inexpensive," said Edward K. Chow, a postdoctoral fellow with the G.W. Hooper Foundation and the University of California, San Francisco, and first author of the paper. "Nanodiamonds possess numerous hallmarks of an ideal drug delivery system and are promising platforms for advancing cancer therapy."


'/>"/>

Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Top scientists unite to develop global scientific strategy Towards An HIV Cure
2. Toward a fast, simple test for detecting cholera rampaging in 40 countries
3. Major step taken toward an open and shared digital brain atlasing framework
4. Warning about benevolent sexism and mens apparently positive attitudes towards women
5. Early Steps Toward an Alzheimers Blood Test
6. Protein disables p53, drives breast cells toward cancer transition
7. University of Utah and Harvard researchers take major step toward first biological test for autism
8. European partnership funds research toward robot aides for the elderly
9. MIT moves toward greener chemistry
10. Study shows behaviors and attitudes towards oral sex are changing
11. Toward safer plastics that lock in potentially harmful plasticizers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/30/2015)... 30, 2015 "Despite having the most ... get better health outcomes than people in other developed ... always safe" states author Dr. John Patrick in his ... Unraveling and Solving the Complexities of Healthcare, John ... to the healthcare policy debate will understand. He arrives ...
(Date:5/30/2015)... Houston, Texas (PRWEB) May 30, 2015 ... week for 2015’s Aesthetic Meeting, sponsored by the American ... many industry vendors on hand was Zeltiq, the parent ... the aesthetic space, CoolSculpting. With blazing growth, the ... , Zeltiq is currently in the ...
(Date:5/30/2015)... New York, New York (PRWEB) May 30, 2015 ... ordered to pay $100 million in punitive and ... http://www.vaginalmeshlawsuit2015.com/ ) plaintiff who suffered serious complications following ... devices. According to a verdict rendered on May ... awarded $25 million in compensatory damages after the ...
(Date:5/30/2015)... May 30, 2015 At 73 years old, ... vibrant health , which she attributes to a lifetime ... of good nutrition with the release of her new book ... Xlibris AU). , “Cook for Health and Longevity” features a ... and mostly organic food . It is designed to ...
(Date:5/30/2015)... Key Housing, a top-rated corporate housing ... their June 2015 featured apartment community: 388 Beale Street. ... Key Housing is helping those people looking for corporate ... of the tightest apartment markets in the United States. ... anyone who requires temporary San Francisco corporate housing is ...
Breaking Medicine News(10 mins):Health News:"Health Attitude", a new book by Dr. John R. Patrick, explains the American healthcare system, what is wrong with it, and how to fix it. 2Health News:"Health Attitude", a new book by Dr. John R. Patrick, explains the American healthcare system, what is wrong with it, and how to fix it. 3Health News:Dr. Paul Vitenas Meets with Zeltiq President and CEO in Montreal 2Health News:Dr. Paul Vitenas Meets with Zeltiq President and CEO in Montreal 3Health News:Boston Scientific Transvaginal Mesh Lawsuit Trial Ends With $100 Million Verdict 2Health News:Boston Scientific Transvaginal Mesh Lawsuit Trial Ends With $100 Million Verdict 3Health News:Boston Scientific Transvaginal Mesh Lawsuit Trial Ends With $100 Million Verdict 4Health News:Lynn Kendall Shows How to ‘Cook for Health and Longevity’ 2Health News:Lynn Kendall Shows How to ‘Cook for Health and Longevity’ 3Health News:San Francisco Corporate Housing Leader Key Housing Designates 388 Beale Street as Featured Community for June 2Health News:San Francisco Corporate Housing Leader Key Housing Designates 388 Beale Street as Featured Community for June 3
... The partnership will bridge diabetes and obesity research ... Aug. 17 Florida Hospital and Burnham Institute for Medical ... advancing Orlando as a hub for medical research. Today, officials ... the appointment of Dr. Steven R. Smith, an internationally-renowned diabetes ...
... the end of July 2009, a team of cardiac surgeons ... of Cardiac Surgery at Heidelberg University Hospital, was the first ... device, the modern version of the DeBakey VAD. The device ... especially effective, gentle and quiet manner. The pump weighs 92 ...
... , First ever-activist toolkit included with an e-book ... RIVER JUNCTION, Vt., Aug. 17 Former Vermont Governor and DNC ... to use technology to empower grassroots activism. Dean has teamed up ... HOWARD DEAN,S PRESCRIPTION FOR REAL HEALTHCARE REFORM: How We Can Achieve ...
... , NEW YORK, Aug. 17 Xanthus ... P.C. The medical group is located in Manhattan on 87th Street ... in maintaining the musculoskeletal health of their patients, so that they ... information please see http://www.manhattanort h opedic.com ...
... ... ... largest providers of specialty products and services for the workers, compensation market, today announced that Lori ... excited to have Lori join PMSI in this critical role. She is a natural fit based ...
... magazines depicted babies in unsafe sleep positions, according to a ... that two-thirds of sleep environments depicted in these magazines were ... Rachel Moon, MD , a pediatrician, and Brandi Joyner at ... infants in 24 magazines with wide circulation among 20- to ...
Cached Medicine News:Health News:Florida Hospital and Burnham Institute Announce New Executive Director and Facility for Clinical Research Institute 2Health News:Florida Hospital and Burnham Institute Announce New Executive Director and Facility for Clinical Research Institute 3Health News:Heidelberg cardiac surgeons implant world's first new DeBakey Heart Assist Device 2Health News:Howard Dean and Chelsea Green Publishing Utilize iPhone Technology to engage and Mobilize Americans in Healthcare Reform Debate. 2Health News:Howard Dean and Chelsea Green Publishing Utilize iPhone Technology to engage and Mobilize Americans in Healthcare Reform Debate. 3Health News:Howard Dean and Chelsea Green Publishing Utilize iPhone Technology to engage and Mobilize Americans in Healthcare Reform Debate. 4Health News:Xanthus Communications Adds New Client Manhattan Orthopedic & Sports Medicine Group, P.C. 2Health News:PMSI Appoints Lori Daugherty as President of Pharmacy Division 2
(Date:5/29/2015)... Fla. , May 29, 2015  Excite Medical ... in 2007.  Over the years, Excite Medical, under the ... be an enduring company, with a solid track record ... and growing client and distributor base.  ... success of Excite Medical has been possible, in large ...
(Date:5/29/2015)... , May 29, 2015 Actinobac Biomed, ... originally funded with investments from Foundation Venture Capital Group ... Bio International 2015 as part of the Start-Up Stadium ... FVCG President James M. Golubieski . ... biotechnology industry, will be held in Philadelphia ...
(Date:5/29/2015)... CANOGA PARK, Calif. , May 29, 2015 /PRNewswire/ ... practices with 1-5 physicians ranks Praxis EMR as #1 ... -based Black Book Market Research LLC conducts a poll ... Satisfaction Survey with the results.    ... satisfaction rating of the 18 performance based criteria used ...
Breaking Medicine Technology:Foundation Venture Capital Group Portfolio Companies to be Highlighted at Bio International in June 2Foundation Venture Capital Group Portfolio Companies to be Highlighted at Bio International in June 3Praxis EMR Ranks #1 for Physician Satisfaction in Black Book's 2015 Survey of Solo and Small Practices 2
... 13 BioMarin,Pharmaceutical Inc. (Nasdaq and SWX: BMRN) ... and distribution partner in Japan, has,submitted a Biologics ... Ministry of Health, Labour and Welfare. "We ... bring the first drug,treatment option to MPS VI ...
... Immtech Pharmaceuticals,Inc. (Amex: IMM ) commented ... Research by a group of researchers at the ... inhibit a key enzyme involved in the DNA,repair ... metabolite (DB75),of Immtech,s proprietary, orally bioavailable prodrug, pafuramidine. ...
Cached Medicine Technology:BioMarin Partner AnGes MG, Inc. Submits BLA to Japanese Ministry of Health 2BioMarin Partner AnGes MG, Inc. Submits BLA to Japanese Ministry of Health 3BioMarin Partner AnGes MG, Inc. Submits BLA to Japanese Ministry of Health 4Furamidine Found to Inhibit a Key Enzyme Involved in Cancer Cell DNA Repair Mechanisms 2Furamidine Found to Inhibit a Key Enzyme Involved in Cancer Cell DNA Repair Mechanisms 3
EXTEND is an absorbable synthetic punctal implant that provides occlusion up to three months. It is packaged 20 implants per box in sizes of .0.3mm, 0.4mm, 0.5mm. A variety pack in also available w...
... The C-VUE 55 Toric Multifocal ... also have presbyopia with all day ... visual acuity at every distance. This ... wide range of parameters with ADDs ...
... based on the principle of convex ... cut., ,This results in the cornea ... of the cut to the end. ... does not vary to the extent ...
... new and innovative stent allows the physician to ... the chair with just topical anesthetic drops., ,The ... is available in three lengths 25mm, 30mm and ... of the stent is an anchor-shaped head to ...
Medicine Products: