Navigation Links
Tiny capsule effectively kills cancer cells
Date:2/6/2013

A tiny capsule invented at a UCLA lab could go a long way toward improving cancer treatment.

Devising a method for more precise and less invasive treatment of cancer tumors, a team led by researchers from the UCLA Henry Samueli School of Engineering and Applied Science has developed a degradable nanoscale shell to carry proteins to cancer cells and stunt the growth of tumors without damaging healthy cells.

In a new study, published online Feb. 1 in the peer-reviewed journal Nano Today, a group led by Yi Tang, a professor of chemical and biomolecular engineering and a member of the California NanoSystems Institute at UCLA, reports developing tiny shells composed of a water-soluble polymer that safely deliver a protein complex to the nucleus of cancer cells to induce their death. The shells, which at about 100 nanometers are roughly half the size of the smallest bacterium, degrade harmlessly in non-cancerous cells.

The process does not present the risk of genetic mutation posed by gene therapies for cancer, or the risk to healthy cells caused by chemotherapy, which does not effectively discriminate between healthy and cancerous cells, Tang said.

"This approach is potentially a new way to treat cancer," said Tang. "It is a difficult problem to deliver the protein if we don't use this vehicle. This is a unique way to treat cancer cells and leave healthy cells untouched."

The cell-destroying material, apoptin, is a protein complex derived from an anemia virus in birds. This protein cargo accumulates in the nucleus of cancer cells and signals to the cell to undergo programmed self-destruction.

The polymer shells are developed under mild physiological conditions so as not to alter the chemical structure of the proteins or cause them to clump, preserving their effectiveness on the cancer cells.

Tests done on human breast cancer cell lines in laboratory mice showed significant reduction in tumor
'/>"/>

Contact: Bill Kisliuk
bkisliuk@support.ucla.edu
310-206-0540
University of California - Los Angeles
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Everyday fish oil capsule may provide kidney-related benefits
2. Evidence that new biomimetic controlled-release capsules may help in gum disease
3. Capsule Endoscopy (Smart/Digital Pills) Market is expected to grow at a CAGR of 17% & to reach $965 Million by 2017 - by MarketsandMarkets
4. Breast cancer effectively treated with chemical found in celery, parsley by MU researchers
5. First-of-its-kind approach nanomedicine design effectively targets cancer with decreased toxicity
6. ShopPharmacyCounter.com Unveils PhenObestin 37.5 to Offset Obesity Effectively
7. Increase Height Naturally
8. Can “Grow Taller 4 Idiots” Help People Boost Their Height Effectively – Health Review Center
9. Burn Fat Fast
10. How "30 Days To Thin" Helps People Melt Fat Naturally and Effectively - Tony Nguyen
11. Candida Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/20/2014)... SATURDAY, Sept. 20, 2014 (HealthDay News) -- As flu ... avoid infection is to get a flu shot and ... A primary care doctor can vaccinate people against ... issues patients may have. Retail stores may provide flu ... medical advice, said Dr. Jorge Parada, medical director of ...
(Date:9/20/2014)... New PharmaPoint Drug Evaluation report, ... 2023?. The asthma market saw very slow growth ... saturated with relatively efficacious standard therapies, such as ... and long-acting beta-agonists (ICS/LABAs), and leukotriene modifiers, and ... the launch of seven novel targeted biologic agents ...
(Date:9/20/2014)... Recently, Best Cheap Hosting USA ... its new website. The new site provides the ... products for customers. Here, people can find a ... decision. Also, it has recommended some excellent web ... of the great web hosting suppliers, InMotion ( ...
(Date:9/20/2014)... 20, 2014 "As a nurse, patients always ... said an inventor from Tamaqua, Pa. "The reason that they ... backs of their chairs. My invention enables them to check ... Oxygen Sensor to make it easier to monitor the contents ... knows when the tank is low. It allows changeovers to ...
(Date:9/20/2014)... New York, NY (PRWEB) September 20, 2014 ... million of their customers may have had their credit card ... late last year, spawning a slew of headline articles ... but those weren’t the only eye opening numbers. , ... numbers were stolen, almost like it’s a way to score ...
Breaking Medicine News(10 mins):Health News:Get a Flu Shot During Checkup, Doctor Says 2Health News:Symbicort Asthma Market Forecasts to 2023 - Overview, Efficacy, Safety & SWOT Analysis in New Report Available at LifeScienceIndustryResearch.com 2Health News:Symbicort Asthma Market Forecasts to 2023 - Overview, Efficacy, Safety & SWOT Analysis in New Report Available at LifeScienceIndustryResearch.com 3Health News:Symbicort Asthma Market Forecasts to 2023 - Overview, Efficacy, Safety & SWOT Analysis in New Report Available at LifeScienceIndustryResearch.com 4Health News:Best Cheap Hosting USA Launches Its New Website And Recommends InMotion To Worldwide People 2Health News:Don’t Let Data Breach Fatigue Cause Dangerous Cyber Security Complacency 2Health News:Don’t Let Data Breach Fatigue Cause Dangerous Cyber Security Complacency 3Health News:Don’t Let Data Breach Fatigue Cause Dangerous Cyber Security Complacency 4Health News:Don’t Let Data Breach Fatigue Cause Dangerous Cyber Security Complacency 5
... in Maryland, USA, has launched a major initiative against the ... all mothers who deliver their babies at the Centre to ... ,Shaking a baby too hard could result in ... ,Nearly 70 percent of shaken baby syndrome cases ...
... prevent bites and therefore don’t prevent disease transmission, according ... be manufactured, advertised or used for mosquito bite and ... lead author A. Ali Enayati, Ph.D., lecturer in medical ... Sari, Iran. ,The review appears in the ...
... surgical robot developed by the University of Washington, leaves for ... in NASA's mission to submerge a surgeon and robotic gear ... system will be put through its paces in an underwater ... in Seattle will guide its movements. ,The 12th ...
... The World Health Organization (WHO) Thursday expressed alarm over ... motorcycles in Asia//, warning that the situation has become ... that young motorcyclists make up a significant percentage of ... countries, such as Cambodia and Malaysia. ,"Factors ...
... benefits of a key ingredient in Cannabis, which may help ... that cannabis could help fight brain, prostate and skin cancers. ... growth by 50%, during studies conducted on mice, suggesting that ... the study, the researchers observed that THC was able to ...
... health workers should focus their efforts on strengthening HIV/AIDS ... not overcome the pandemic, Kevin De Cock, director of ... deputy director of UNAIDS, said on Tuesday during a ... comments follow the release of a report on Tuesday ...
Cached Medicine News:Health News:Counseling to Mothers Against too Much Shaking of Children 2Health News:Electronic Mosquito Repellents Fail to Prevent Malaria Transmission 2Health News:Robotic Surgeon to Team Up With Doctors, Astronauts on NASA Mission 2Health News:Robotic Surgeon to Team Up With Doctors, Astronauts on NASA Mission 3Health News:U.N. Officials Call on Countries To Strengthen HIV/AIDS Prevention Efforts 2
(Date:9/19/2014)... Sept. 19, 2014  Lpath, Inc. (NASDAQ: ... lipid-targeted therapeutics, announced today that it has entered ... of common stock and 3,605,042 unregistered warrants in ... for one registered share of common stock and ... of common stock will be $3.475.  The warrants ...
(Date:9/19/2014)... September 19, 2014 Aufgrund ... den äußerst erfolgreichen Serialisierungs-Countdown-Kalender aktualisiert, der jetzt auch ... PDF, verfügbar unter pharmaserialisation.com , zeigt die ... jeweils in Kraft treten. Für international ... länger um das "ob", sondern darum, "wann" sie ...
(Date:9/19/2014)... LOS ANGELES , Sept. 19, 2014  CytRx ... and development company specializing in oncology, today announced that ... will present at BioCentury,s 2014 NewsMakers in the Biotech ... p.m. Eastern Time. The conference will take place at ... City . A live and archived ...
Breaking Medicine Technology:Lpath, Inc. Announces $12.5 Million Registered Direct Offering 2Lpath, Inc. Announces $12.5 Million Registered Direct Offering 3Pharma IQ stellt weltweite Serialisierungsfristen in seinen Countdown-Kalender 2014 - 2018 2CytRx to Present at BioCentury's 2014 NewsMakers in the Biotech Industry Conference 2CytRx to Present at BioCentury's 2014 NewsMakers in the Biotech Industry Conference 3
... as Chief Strategic Officer -- SHENZHEN, China, Sept. 7 /PRNewswire-Asia-FirstCall/ -- ... ... ... var first_result; // Results are keyed by longUrl, so we need to grab the first one. for ...
... Dyadic International, Inc. ("Dyadic") (Pink Sheets: ... on the discovery, development, manufacture and sale of ... industrial enzyme and biopharmaceutical industries, today announced that ... complete its previously announced private placement of convertible ...
Cached Medicine Technology:Mindray Appoints Mr. Minghe Cheng as Chief Strategic Officer 2Mindray Appoints Mr. Minghe Cheng as Chief Strategic Officer 3Mindray Appoints Mr. Minghe Cheng as Chief Strategic Officer 4Mindray Appoints Mr. Minghe Cheng as Chief Strategic Officer 5Mindray Appoints Mr. Minghe Cheng as Chief Strategic Officer 6Mindray Appoints Mr. Minghe Cheng as Chief Strategic Officer 7Dyadic International Raises Additional $1 Million to Complete $4 Million Convertible Note Offering 2
... InstaCheck® multi-drug test device provides ... easily. Negative results can be ... 3 minutes; positive results require ... one-time urine sample application will ...
... Tests are available in 14 configurations including ... using Microgenics Antibody Technology, the SureStep™ MDMA ... care immunoassay targeted to detect MDMA that ... MDEA but no cross-reactivity to any isomer ...
... QuickScreen™ At Home Drug Test is the first ... for home use. The kit includes a rapid ... read instructions, a handbook with frequently asked questions ... sample to the laboratory if the screening device ...
... popular onsite test! QuickScreen™ multi-panel dip cards ... and your choice of any conceivable combination ... total flexibility for your drug testing program. ... and the built-in timer tells you when ...
Medicine Products: