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Tiny RNA shown to cause multiple types of leukemia
Date:11/29/2010

e is not one good target, but I assume I will find a combination of targets."

Once identified, Bousquet hopes that miR-125b or its gene targets could be exploited therapeutically. Lodish, however remains skeptical.

"We know that miR-125b could trigger leukemia," says Lodish. "But what we don't know is once the cancer has progressed, whether you still need miR-125b. If established leukemia doesn't require miR-125b overexpression, then targeting the microRNA would have little effect."


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Contact: Nicole Giese
giese@wi.mit.edu
617-258-6851
Whitehead Institute for Biomedical Research
Source:Eurekalert

Page: 1 2 3

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