Navigation Links
Tinnitus study signals advance in understanding link between loud sounds exposure and hearing loss
Date:2/14/2014

A research team investigating tinnitus, from the University of Leicester, has revealed new insights into the link between the exposure to loud sounds and hearing loss.

Their study, published this week in Neuroscience, helps to understand how damage to myelin a protection sheet around cells - alters the transmission of auditory signals occurring during hearing loss.

The three-year study was derived from a PhD studentship funded by Action on Hearing Loss. It was led by Dr Martine Hamann, Lecturer in Neurosciences at the University's Department of Cell Physiology and Pharmacology.

Dr Hamann said: "A previous publication has shown that exposure to loud sound damages the myelin which is the protection sheet around cells. We have now shown the closer links between a deficit in the "myelin" sheath surrounding the auditory nerve and hearing loss. It becomes obvious why hearing loss is correlated with auditory signals failing to get transmitted along the auditory nerve.

"Understanding cellular mechanisms behind hearing loss and tinnitus allows for developing strategies to prevent or alleviate the symptoms of deafness or tinnitus - for example by using specific drug therapies.

"This new study is particularly important because it allows us to understand the pathway from exposure to loud sound leading to the hearing loss. We now have a better idea about the mechanisms behind the auditory signals failing to get transmitted accurately from the cochlea to the brain. Consequently, targeting myelin and promoting its repair after exposure to loud sound could be proven effective in noise induced hearing loss."

Dr Hamann added that getting to dissect the cellular mechanisms underlying hearing loss is likely to bring a very significant healthcare benefit to a wide population.

She said: "Understanding mechanisms responsible for hearing loss represents a significant unmet need that is likely to increase as the incidence of the disorder increases due to an ageing population and the increasing impact of recreational and workplace noise.

"I am very excited by this research. The work will help prevention as well as progression into finding appropriate cures for hearing loss and possibly tinnitus developing from hearing loss."

Dr Hamann's team at the University of Leicester included Thomas Tagoe who performed all the electrophysiological experiments, Matt Barker and Natalie Allcock who performed the electron microscopy and the imaging experiments. Andrew Jones, a project student in the lab performed computer modelling.

Dr Ralph Holme Action on Hearing Loss' Head of Biomedical Research says: ''We know that exposure to loud noise can lead to hearing loss. Protecting your ears should always be the first line of defence, but medical treatments to combat unavoidable or accidental exposure to noise are also urgently needed. The research we have been funding at University of Leicester makes an important contribution to increasing our understanding of how noise damages the hearing system - knowledge we hope will ultimately lead to medical treatments for this common type of hearing loss."


'/>"/>

Contact: Martine Hamann, Ph.D.
mh86@le.ac.uk
University of Leicester
Source:Eurekalert

Related medicine news :

1. New Hearing Healthcare Blog from Geneva Hearing Services in Geneva Illinois Connects Local Residents with Vital Information on Hearing Aids, Hearing Loss and Tinnitus
2. Tinnitus Miracle: Review on a New Treatment to Tackle Tinnitus has been Published by ReviewedToday.org
3. Tinnitus Control Ear Ringing Relief Company Now Offers an Extra Discount as New Year Special
4. How To Cure Tinnitus
5. Can “Tinnitus Miracle” Help People Stop Ringing In The Ears? - hynguyenblog.com
6. Tinnitus Miracle Treatment Review Exposes the Fastest Way to Cure Tinnitus Naturally
7. New Study Improves Understanding of Tinnitus Perception by Patients
8. Tinnitus Global Clinical Trials Review, H2, 2013
9. Tinnitus Miracle Review Exposes 5 Step Method to Eliminate Tinnitus Permanently
10. Tinnitus Miracle Reveals Holistic Program for Permanent Relief
11. Tinnitus Miracle Review Discloses Effective Way to Eliminate Disturbing Ear Noise
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/9/2016)... ... February 09, 2016 , ... ... officially been won. A team from 21st Century Medicine (21CM) ( http://www.21cm.com/ ... preserve the delicate neural circuits of an intact rabbit brain for extremely long-term ...
(Date:2/8/2016)... ... February 08, 2016 , ... ... Nutrition into the Food & Beverage and Dietary Supplement ... partner throughout Canada and USA geographies east of the Rocky Mountains since 2012. ...
(Date:2/8/2016)... ... ... famous for gift giving with flowers, chocolates and other tokens of affection meant to remind ... than 5.6 million Americans suffering with Alzheimer’s, those store bought gifts - no matter ... they’ve led and the people they’ve touched. , That’s why Give To ...
(Date:2/8/2016)... , ... February 08, 2016 , ... If you are ... to handle, you are not alone. According to the Center for Disease Control and ... stroke, type 2 diabetes and certain types of cancer, some of the leading causes ...
(Date:2/8/2016)... IN (PRWEB) , ... February 08, 2016 , ... ... the Indianapolis, IN metro area, has selected the latest beneficiary of their ongoing ... organization dedicated to preventing bullying in area schools. Donations are now being accepted ...
Breaking Medicine News(10 mins):
(Date:2/9/2016)... Mast Therapeutics, Inc. (NYSE MKT: MSTX), ... disease and heart failure, today announced that it intends to ... stock in an underwritten public offering.  The offering is subject ... assurance as to whether or when the offering may be ... the offering.   --> --> ...
(Date:2/9/2016)... 9, 2016 The new report "Global Diagnostic Ultrasound Devices ... Consulting group reveals that global diagnostic ultrasound devices market was valued ... US$ 7,466.3 million by 2019 at a CAGR of 6.8% from ... ultrasound market has been analyzed for six geographies of ... Asia-Pacific , Latin America , ...
(Date:2/9/2016)... , Feb. 9, 2016 The leader ... that AcceleDent ® is the recipient of the ... category. An FDA-cleared, Class II medical device that speeds ... percent and relieves pain often associated with treatment, AcceleDent ... participated in the annual Orthotown survey of ...
Breaking Medicine Technology: