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Tight Blood Pressure Control Doesn't Help All Diabetics: Study
Date:7/6/2010

ary artery disease. The participants were part of a larger trial investigating whether specific medication regimens were better than others for preventing heart attacks and other long-term heart problems.

Volunteers first received either a calcium antagonist or beta blocker, then an ACE inhibitor or a diuretic or both. The goal was to reach blood pressure levels of 130/85.

Individuals in the study who had blood pressure between 130 mm Hg and 140 mm Hg (usual control) and those who maintained tight control (less than 130 mm Hg) had roughly the same rate of cardiovascular events.

And, for the first time, the results showed that individuals with systolic blood pressure under 120 had a 15 percent higher risk of dying than those with the higher blood pressure readings.

"We don't need to push below 130 so maybe we save a blood pressure medication and save some of those adverse effects associated with extra [blood pressure] medication and concentrate on some other goals that are still important in patients with diabetes," said Cooper-DeHoff.

The trial was partially funded by Abbott Laboratories.

More information

The American Diabetes Association has more on living with type 2 diabetes and high blood pressure.

SOURCES: Rhonda Cooper-DeHoff, Pharm.D., associate professor, department of pharmacotherapy and translational research and division of cardiovascular medicine, Colleges of Pharmacy and Medicine, University of Florida, Gainesville; July 7, 2010, Journal of the American Medical Association


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