Navigation Links
Tight Blood Pressure Control Doesn't Help All Diabetics: Study
Date:7/6/2010

By Amanda Gardner
HealthDay Reporter

TUESDAY, July 6 (HealthDay News) -- Lower may not be better when it concerns blood pressure levels in type 2 diabetics who also have heart disease.

New research finds that patients with diabetes and coronary artery disease did not have fewer strokes or heart attacks, and actually were more likely to die when their blood pressure was maintained under 130 mm Hg, compared to patients with "usual blood pressure control," putting them in the 130 to 140 range.

In healthy adults, blood pressure levels of 120/80 are recommended.

"We found that after a mean follow-up of just under three years in patients with diabetes and coronary artery disease, lowering systolic blood pressure [the top number] to less than 130 . . . did not have any benefit compared to lowering blood pressure to between 130 and 140," said Rhonda Cooper-DeHoff, lead author of the study published in the July 7 issue of the Journal of the American Medical Association.

These findings, along with similar data recently released from the large ACCORD study, would suggest that "lowering blood pressure intensively does not provide any benefit over and above usual blood pressure reduction," said Cooper-DeHoff, who is associate professor of pharmacotherapy and translational research and division of cardiovascular medicine at the Colleges of Pharmacy and Medicine, University of Florida, Gainesville.

Time would be better spent focusing on other modifiable heart disease risk factors, such as cholesterol, she advised.

Various organizations, including the American Diabetes Association, currently recommend that diabetics keep their blood pressure under 130/80 mm Hg, but it's been less clear what to recommend for patients with type 2 diabetes and coronary artery disease.

To this end, the researchers involved in the new study analyzed data on 6,400 type 2 diabetics aged 50 or over who also had coronary artery disease. The participants were part of a larger trial investigating whether specific medication regimens were better than others for preventing heart attacks and other long-term heart problems.

Volunteers first received either a calcium antagonist or beta blocker, then an ACE inhibitor or a diuretic or both. The goal was to reach blood pressure levels of 130/85.

Individuals in the study who had blood pressure between 130 mm Hg and 140 mm Hg (usual control) and those who maintained tight control (less than 130 mm Hg) had roughly the same rate of cardiovascular events.

And, for the first time, the results showed that individuals with systolic blood pressure under 120 had a 15 percent higher risk of dying than those with the higher blood pressure readings.

"We don't need to push below 130 so maybe we save a blood pressure medication and save some of those adverse effects associated with extra [blood pressure] medication and concentrate on some other goals that are still important in patients with diabetes," said Cooper-DeHoff.

The trial was partially funded by Abbott Laboratories.

More information

The American Diabetes Association has more on living with type 2 diabetes and high blood pressure.

SOURCES: Rhonda Cooper-DeHoff, Pharm.D., associate professor, department of pharmacotherapy and translational research and division of cardiovascular medicine, Colleges of Pharmacy and Medicine, University of Florida, Gainesville; July 7, 2010, Journal of the American Medical Association


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Tight Blood Sugar Control in Older Diabetics May Not Reduce Heart Risk
2. Tight Blood Sugar Control May Not Harm Diabetics
3. FDA Tightens Oversight of Home Medical Devices
4. IBM Enterprise CloneDR Helps Enterprises Transform Bloated COBOL into Clean, Tight, and Maintainable Code
5. FDA Tightens Controls on Anemia Drugs
6. Tight Blood Sugar Control May Raise Risk of Death
7. Tighter Blood Sugar Control Not Best for Some Diabetics
8. Researchers identify factors behind blood-making stem cells
9. Diagnostic blood test can identify rare lung disease
10. Insulin Pump With Blood Sugar Sensor May Improve on Injections
11. Sensor and insulin pump results in better blood-sugar control in all age groups with diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2017)... ... 19, 2017 , ... DMG Productions, producers of the award ... an upcoming episode, slated to air fourth quarter 2017. Check your local listings ... a company committed to supporting dentistry using the most technologically advanced restorative materials ...
(Date:8/19/2017)... (PRWEB) , ... August 19, 2017 , ... Curl Keeper® ... of NaturallyCurly.com® The Curl Leaders, Editors’ Choice 2017 Award for the second year in ... for hair stylists and curlies alike was voted Best Moisturizer for Type 2 Wavies ...
(Date:8/19/2017)... ... August 19, 2017 , ... “Congratulations! It's A Boy! God’s Gift: ... both their parents and God. “Congratulations! It's A Boy! God’s Gift: A Story of ... from Long Island, New York. , Published by Christian Faith Publishing, Dale Anthony and ...
(Date:8/18/2017)... NY (PRWEB) , ... August 18, 2017 , ... ... of “Vision & Hearing” campaign, advocating for active, healthy lifestyles and highlighting the ... available for individuals with hearing impairments and shares the latest innovations in hearing ...
(Date:8/18/2017)... VA (PRWEB) , ... August 18, 2017 , ... ... asset protection services and financial consultations to communities throughout the greater DC region, ... K9 with the goal of rescuing local animals and training them to be ...
Breaking Medicine News(10 mins):
(Date:8/2/2017)... Aug. 2, 2017 CaryRx, a next-generation full-service pharmacy, ... service for patients in the Washington D.C. ... pharmacy by providing delivery of medications through the convenience of ... delivery or delivered within one hour to any location in ... to bring this invaluable service to Washington D.C. ...
(Date:7/28/2017)... July 28, 2017 Hill-Rom Holdings, Inc. ("Hill-Rom") ... third quarter ended June 30, 2017, and updated its ... For the fiscal third quarter, Hill-Rom ... $0.68 per diluted share in the prior-year period. These ... $0.39 per diluted share primarily related to the non-cash ...
(Date:7/26/2017)... 2017  Radium Medical Aesthetics, a leading medical aesthetic clinic in ... by effectively addressing several skin conditions from the inside. ... and more fragile. The skin becomes more transparent due to the ... harmful UV rays from the sun contributes to aging skin, causing ... ...
Breaking Medicine Technology: