Navigation Links
Thyroid hormone analogue for treating high cholesterol
Date:3/11/2010

MANHASSET, NY An experimental thyroid drug reduces cholesterol without the troublesome side effects experienced by some people on statins, according to a study published today in The New England Journal of Medicine. An international team of investigators at Johns Hopkins Medical Institutions, the Karolinska University Hospital and Institute, and The Feinstein Institute for Medical Research tested a substance called Eprotirome in patients with high cholesterol.

Following 189 people with high cholesterol over a three-month period, they observed that it lowered cholesterol levels without the classic thyroid risks to the heart and bone, The study was supported by Karo Bio in Sweden, a company that is developing the drug for its cholesterol-lowering effects.

Over three decades, Irwin Klein, MD, an endocrinologist at the Feinstein Institute, has been at the forefront of researching the connection between thyroid and heart health. It seemed that people with underactive thyroid glands also had high cholesterol levels. These high cholesterol levels were dramatically reduced with thyroid hormone replacement. But the problem in using thyroid hormone for cholesterol lowering is the side effects of an overactive thyroid gland: people can become anxious and have heart palpitations, muscle weakness and bone thinning.

Scientists spent years trying to develop thyroid analogs that lowered lipids without unwanted side effects. American scientists, including Dr. Klein and John D. Baxter, MD, a senior member of The Methodist Hospital Research Institute, have been working with Karo Bio scientists to solve this problem. They landed on one in particular that lowered cholesterol without any of the problems with the traditional thyroid medicines. Phase I studies showed the drug safe.

In the current Phase II study, they reported that it was both safe and effective in lowering cholesterol. What is not known from this study is whether this lowe
'/>"/>

Contact: Jamie Talan
jtalan@nshs.edu
516-562-1232
North Shore-Long Island Jewish (LIJ) Health System
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Thyroid Hormone Analogue for Treating High Cholesterol
2. Thyroid Disease: The Hidden Epidemic
3. No End In Sight To The Armour Thyroid Shortage?
4. Stain repellent chemical linked to thyroid disease in adults
5. It's January...Do You Know Where Your Thyroid Is? Thyroid Awareness Month Focuses on Millions of Undiagnosed Americans with Thyroid Problems
6. Low Thyroid Levels May Up Need for Assisted Delivery
7. Pregnancy Complication May Be Linked to Thyroid Problems
8. Thyroid Cancer Higher in Volcanic Areas
9. Newly revised guidelines for managing thyroid cancer published in Thyroid journal
10. Thyroid surgery safe for older patients, study finds
11. Studies Evaluate Thyroid Treatment During Pregnancy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/19/2013)... TX (PRWEB) June 19, 2013 Chrysler made ... concerning a recall of 2.7 million Jeeps. The Jeep models ... 2002-2007 Jeep Liberty, which according to the NHTSA are vulnerable ... gas tanks in these models are rear-mounted and have been ... agency findings show the Grand Cherokee with 32 rear-end crashes, ...
(Date:6/19/2013)... June 19, 2013 Amber Roberson ... RWI Benefits, LLC, Native Care Health, LLC and ... of Health Underwriters’ (NAHU) new professional development course ... (PPACA). This continuing education course for agents has ... will receive eleven education credits from the Missouri ...
(Date:6/19/2013)... New York, New York (PRWEB) June 19, 2013 ... involving pancreatitis and pancreatic cancer continue to mount in ... the U.S. Food & Drug Administration (FDA) recently held ... other diabetes drugs known as incretin mimetics. According ... may seek additional data from the makers of Januvia ...
(Date:6/19/2013)... 2013 The Journal of Parasitology – ... computer software, it creates questions of ethics. For scientific ... an already published case shows, scientific publications need clear ... The Journal of Parasitology features a commentary ... 2004 article published in the Journal of the New ...
(Date:6/19/2013)... led by researchers at The University of Texas MD ... show remarkable promise for the treatment of relapsed or ... interim findings of the 18-center Phase 2 study were ... Medicine . Previous interim findings were presented in December ... Meeting and Exposition. , Unprecedented results, fewer ...
Breaking Medicine News(10 mins):Health News:Zinda & Davis PLLC: Why the Chrysler Recall Refusal Matters And May Set a Dangerous Precedent 2Health News:Zinda & Davis PLLC: Why the Chrysler Recall Refusal Matters And May Set a Dangerous Precedent 3Health News:RWI Benefits, LLC Becomes PPACA Certified 2Health News:Januvia Lawsuit News: Bernstein Liebhard LLP Comments on Recent FDA Meeting to Discuss Safety of Januvia and Other Incretin Mimetics 2Health News:Januvia Lawsuit News: Bernstein Liebhard LLP Comments on Recent FDA Meeting to Discuss Safety of Januvia and Other Incretin Mimetics 3Health News:Altered Photo in Journal Article Illustrates the Need for Manipulation Guidelines 2Health News:Ibrutinib continues strong showing against mantle cell lymphoma 2
... it has been found that students who are well fed ... ,The study was done at Cornell's Early Childhood Centre. ... development especially in reading. ,This phenomenon is ... do not have enough to eat due to poverty in ...
... treatment medicine acclaimed the world over Tamiflu now will be ... firm Roche to make a generic version of its anti-flu ... The company is Hetero Drugs. ,The drug is ... future pandemic of bird flu in humans. ,The Swiss drugs ...
... Indian American Scientist Dr. Henry Daniell has produced a ... plant. The new gene transfer technique to tobacco plants ... symptoms and rashes involved in conventional anthrax vaccine fermentation ... of 360 million doses in one acre of tobacco ...
... company that extracts chemicals from plants, plans to use used ... drug that treat bird flu.// ,The trees contain ... Biolyse said today in a statement. The acid is used ... star anise trees in China, Biolyse said. ,Tamiflu ...
... larger brains have better intellect, according to McMaster University’s ... said that there were differences between women and men. ... Brain also said, said that in women, verbal intelligence ... of the verbal IQ score. ,However, ...
... of the rising rates of infection with C.difficile among ... mutation of the microorganism into a more virulent form.// ... manifest in individuals with resistance to antibiotics. ... non-hospitalized patients has created much panic among the scientific ...
Cached Medicine News:Health News:Christmas trees to yield key Tamiflu ingredient 2Health News:Rising Rates Of C.Difficile Infection Among Non-Hospitalized Patients 2
(Date:6/19/2013)... 19, 2013 Ellen MacArthur ... kommande tre åren kommer att vara en partner ... cirkulär ekonomi. Efter stiftelsens framgångsrika partnerskap ... Grid, kommer Philips att ansluta sig som partner ... i sin egen verksamhet och stödja stiftelsens arbete ...
(Date:6/19/2013)... , June 19, 2013 The Physician-Patient Alliance ... alarm fatigue. The need to urgently address this ... its Sentinel Event Alert #50 , "Medical device alarm safety ... database, between January 2008 and June 2012, there were 98 ... resulted in death (82%) , 13 resulted in permanent ...
(Date:6/19/2013)... , June 19, 2013   BioCision , ... standardization and handling in many areas of medical ... new patents by the U.S. Patent Office that ... developed to standardize sample handling to ensure the ... in common laboratory procedures. Patent ...
Breaking Medicine Technology:Ellen MacArthur Foundation presenterar Philips som global partner vid det konstituerande internationella toppmötet om cirkulär ekonomi 2Ellen MacArthur Foundation presenterar Philips som global partner vid det konstituerande internationella toppmötet om cirkulär ekonomi 3Three Lessons Learned to Reduce Alarm Fatigue and Improve Alarm Management and Patient Safety in Hospitals 2Three Lessons Learned to Reduce Alarm Fatigue and Improve Alarm Management and Patient Safety in Hospitals 3BioCision Announces Two New U.S. Patents for Thermo-Conductive Products that Standardize Sample Handling in Laboratory Research 2
... April 14, 2011 /PRNewswire-Asia/ -- Winner Medical Group Inc. ... Company") a leading manufacturer of medical dressings, medical disposables ... in China, today announced that the Company will attend ... Exhibition to be held in the Shenzhen Convention and ...
... Reportlinker.com announces that a new market research ... Endometrial Cancer Therapeutics - Pipeline Assessment and ... http://www.reportlinker.com/p0479825/Endometrial-Cancer-Therapeutics---Pipeline-Assessment-and-Market-Forecasts-to-2017.html Endometrial Cancer Therapeutics - ... Summary GlobalData, the ...
Cached Medicine Technology:Winner Medical to Attend 65th CMEF Spring11 Exhibition in Shenzhen 2Winner Medical to Attend 65th CMEF Spring11 Exhibition in Shenzhen 3Winner Medical to Attend 65th CMEF Spring11 Exhibition in Shenzhen 4Reportlinker Adds Endometrial Cancer Therapeutics - Pipeline Assessment and Market Forecasts to 2017 2Reportlinker Adds Endometrial Cancer Therapeutics - Pipeline Assessment and Market Forecasts to 2017 3Reportlinker Adds Endometrial Cancer Therapeutics - Pipeline Assessment and Market Forecasts to 2017 4Reportlinker Adds Endometrial Cancer Therapeutics - Pipeline Assessment and Market Forecasts to 2017 5Reportlinker Adds Endometrial Cancer Therapeutics - Pipeline Assessment and Market Forecasts to 2017 6Reportlinker Adds Endometrial Cancer Therapeutics - Pipeline Assessment and Market Forecasts to 2017 7Reportlinker Adds Endometrial Cancer Therapeutics - Pipeline Assessment and Market Forecasts to 2017 8Reportlinker Adds Endometrial Cancer Therapeutics - Pipeline Assessment and Market Forecasts to 2017 9Reportlinker Adds Endometrial Cancer Therapeutics - Pipeline Assessment and Market Forecasts to 2017 10
The Advia 60 is designed to deliver powerful performance in a small package....
AcT 5diff OV enables low-volume labs to advance to 5-part differential analysis at an affordable price. This analyzer delivers accurate test results and a user-friendly software interface in a compac...
... three-dimensional VCS technology, providing ... efficiency in white cell ... With its reputation for ... is an affordable solution ...
... 750 analyzer is equipped with ... random access capabilities. These advancements ... pre-sorting of samples and speed ... system, you can improve overall ...
Medicine Products: