Navigation Links
Thyroid Function at High End of Normal Tied to Miscarriage Risk
Date:6/22/2010

Pregnant women should be screened according to stricter standards, experts suggest

TUESDAY, June 22 (HealthDay News) -- Testing in the upper half of what is currently considered a normal range for thyroid function can nonetheless be problematic for pregnant women, who face an increased risk for miscarriage as a result, new research suggests.

The study is the first to link what has previously been considered normal thyroid function to miscarriage risk, according to co-investigator Dr. Alex Stagnaro-Green, a senior associate dean for education at the George Washington University School of Medicine and Health Sciences in Washington, D.C.

The newly observed risk does not involve the presence of thyroid peroxidase antibodies, something that prior research has linked to a threat for miscarriage. An underactive thyroid has also been associated with risk of miscarriage, the study authors noted in a news release from the Endocrine Society.

"There has been an ongoing discussion as to whether or not the normal range for thyroid function tests is too broad," Stagnaro-Green said in the news release. "This study provides clear evidence that the normal range for thyroid function tests during pregnancy needs to be redefined."

The findings are scheduled for presentation Tuesday at the Endocrine Society Annual Meeting and Expo in San Diego.

The researchers' concerns center on the use of the thyroid stimulating hormone blood test. Since 2007, pregnant women reading above the upper limit of 2.5 milli-international units per liter (mIU/L) in the first trimester and 3 mIU/L in the second and third trimesters have been deemed to have an "underactive thyroid," and thus a higher risk for miscarriage.

However, the authors pointed out that many doctors do not actually follow this guideline, instead relying on the non-pregnant "normal range" marker of 4.5 or 5 mIU/L as an upper limit.

Stagnaro-Green and colleagues sought to get a handle on what range is, in fact, safe for pregnant women, by tracking the first-trimester thyroid tests and pregnancy outcomes of more than 4,100 women attending two community hospitals in Italy.

The team found that having a high-end normal-range thyroid reading (above 2.5, but below 5) did not increase the risk for having a pre-term delivery, however, miscarriage rates among women with a high-normal range were "significantly higher" (about 6 percent versus 3.6 percent) than for women with the recommended below-2.5 thyroid reading for pregnant women.

"This leads us to think that all pregnant women should be screened for thyroid function and any abnormalities treated," Stagnaro-Green concluded in the news release.

More information

For more on thyroid disease in pregnancy, visit the U.S. National Endocrine and Metabolic Diseases Information Service.



-- Alan Mozes



SOURCE: The Endocrine Society, news release, June 22, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Flame Retardant May Up Risk of Thyroid Problems in Pregnancy
2. Flame retardant linked to altered thyroid hormone levels during pregnancy
3. SNM 2010 image of the year: Molecular imaging shows parathyroid disease in greater detail
4. Thyroid ultrasound takes center stage at Caesars Palace
5. Experts Divided on Whether to Treat Thyroid Cancer
6. Demonstrated in vivo the transfer of maternal thyroid hormones to the fetus
7. Thyroid condition increases stroke risk in young adults
8. Overactive Thyroid Linked to Stroke in Young Adults
9. Thyroid hormone analogue for treating high cholesterol
10. Thyroid Hormone Analogue for Treating High Cholesterol
11. Thyroid Disease: The Hidden Epidemic
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Thyroid Function at High End of Normal Tied to Miscarriage Risk
(Date:2/17/2017)... ... February 17, 2017 , ... ... sustainable systems change designed to further positively impact the health and wellness of ... has long considered it our duty to seriously consider releasing our assets beyond ...
(Date:2/17/2017)... ... February 17, 2017 , ... Empowering ... Francis' goals for each and every seminar, session and class she offers. ... five different brainwave tools which help energize creativity, focus mental functions, enhance athletic ...
(Date:2/17/2017)... ... February 17, 2017 , ... ... 2017 season , Trinity Health and the U.S. Soccer Foundation announced today that ... in underserved communities. Soccer for Success, the Foundation’s soccer mentoring program, teaches kids ...
(Date:2/17/2017)... ... 17, 2017 , ... Cancer diagnostics workflow solution provider Inspirata, ... – 22 in San Francisco. As part of the Tri-Conference expo, which is ... solution, as well as its new precision medicine platform, “Crosswalk Insight: Oncology™.” , ...
(Date:2/17/2017)... ... February 17, 2017 , ... ... planning assistance to families and business owners in the greater Fort Lauderdale metropolitan ... organization. , For more than 30 years, LifeNet 4 Families has provided ...
Breaking Medicine News(10 mins):
(Date:2/17/2017)... 2017 Theravance Biopharma, Inc. (NASDAQ: ... today announced the presentation of positive clinical data ... pan-Janus kinase (JAK) inhibitor designed to be intestinally ... the European Crohn,s and Colitis Organization (ECCO). In ... from its completed Phase 1 study of single-ascending ...
(Date:2/17/2017)... , Feb. 17, 2017  In partnership with ... Friends for Good Health , The Jack Brewer ... filled with millions of dollars, worth of medicine to ... Haiti . IHI is a non-profit dedicated to treating ... is extremely active in Haiti ...
(Date:2/17/2017)...  Noble Capital Markets announced today that it has ... EPIX ). The report was issued by Noble,s ... ESSA Pharmaceuticals is a clinical stage biopharmaceutical ... Its lead compound EPI-506, is a small molecule oral ... androgen receptor, thereby has potential to overcome some of ...
Breaking Medicine Technology: