Navigation Links
ThromboGenics Begins Preclinical Development of Anti-VPAC Antibody for Thrombocytopenia
Date:11/13/2007

LEUVEN, Belgium, November 14 /PRNewswire/ --

- Key Research Findings Published in the Leading Medical Journal `Blood' Validate Drug Target

ThromboGenics NV (Euronext Brussels: THR), a biotechnology company focused on vascular disease, announces today that it will progress with the development of its novel anti-VPAC(1) antibody for the treatment of thrombocytopenia, including chemotherapy-induced thrombocytopenia.

Thrombocytopenia, which is the reduced number of platelets in blood, is a common severe side effect of chemotherapy and increases the risk of bleeding and severity of haemorrhage, therefore causing the delay or even discontinuation of treatment in cancer patients. There is a high medical need to find a therapeutic that could reduce thrombocytopenia by accelerating platelet production. Blood transfusion, the current standard of care for this condition, offers only a temporary solution for these patients and is associated with significant cost and risk.

Researchers at the University of Leuven and ThromboGenics have developed a novel therapeutic approach, showing that the inhibition of VPAC could stimulate the production of platelets. ThromboGenics has now identified and selected a lead antibody against VPAC to enter preclinical development. VPAC is a receptor present at the surface of bone marrow cells called megakaryocytes, which, when mature, produce platelets. Research published yesterday in Blood describes how the inhibition of VPAC could promote megakaryocyte differentiation. Blood is the official journal of the American Society of Hematology (ASH).

Prof. Desire Collen, CEO and Chairman of ThromboGenics, commented: "Thrombocytopenia is a severe complication of cancer patients receiving chemotherapy, and for which there is little therapeutic alternative. I am very pleased to advance our thrombocytopenia programme to preclinical development, which I hope will confirm the potential of our approach published in Blood. Thi
'/>"/>

SOURCE ThromboGenics NV
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine news :

1. Provectus Pharmaceuticals, Inc. Begins Phase 2 Clinical Trial for Metastatic Melanoma
2. PA Department of Public Welfare Begins Outreach to Medical Assistance Consumers Following Burglary at State Office Building
3. China Shenghuo Pharmaceutical Holdings, Inc. Begins Full-Scale Launch of 12Ways(R) Chinese Herbal Skin Care Product Line
4. Most comprehensive study of mercury in dental fillings begins
5. Eye Safety Begins at Home
6. MetLife Foundation Begins New Phase of Award-Winning Parenting Skills Campaign in Collaboration with the Partnership for a Drug-Free America(R)
7. OmniGuide Begins European Commercialization
8. From Microscope to Stethoscope: the MUHCs distinguished public lecture series begins a second seaso
9. From microscope to stethoscope: The MUHCs public lecture series begins its 2nd season tomorrow
10. North Shore-LIJ Health System Begins Online Posting of Hospital Infection Rates, Other Performance Information
11. Healthy Weight Loss Begins With What You Permit to Enter Your Mind, More So Than Even Your Mouth!
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... 2013 Memorial Day Focus Spotlight on ... been a part of the U.S. Military for more ... preceding it, these men and women will be honored ... of America. As veterans transition to civilian life, ... the workplace chaplaincy world. , Marketplace Chaplains, America’s ...
(Date:5/23/2013)... 23, 2013 Susquehanna Health ... a comprehensive babysitting training course for adolescents age 11 ... by Indianapolis pediatrician Dr. Patricia Keener after a colleague’s ... an adult sitter who didn’t know how to provide ... program with a medical basis that aims to reduce ...
(Date:5/23/2013)... Mayo Clinic researchers have used next generation genomic analysis ... cancer tumors have similar genetic origins, which may help ... in the journal Cancer Research . , "This ... next generation sequencing in adjacent Gleason patterns in the ... in pathology," says ,John Cheville, M.D., Mayo Clinic pathologist ...
(Date:5/23/2013)... CA (PRWEB) May 23, 2013 Dr. ... her new charitable organization in Orange County, OCCares , ... in Orange County. The event details are as follows: ... Orangewood Academy Auditorium, 13732 Clinton Street, Garden Grove, CA 92843 ... pop crossover music by Christian vocalists Charmaine & Jonathan Thulin. ...
(Date:5/23/2013)... 2013 Click here to read the ... are increasingly seeing their success develop through merger ... according to new research carried out by MaRS ... company has compiled its research into a series of ... the research have shown the general trend that the ...
Breaking Medicine News(10 mins):Health News:Memorial Day Focus Spotlight on Military Chaplains Transitioning in the Marketplace 2Health News:Memorial Day Focus Spotlight on Military Chaplains Transitioning in the Marketplace 3Health News:Susquehanna Health Offers Safe Sitter Course for Tweens and Teens 2Health News:Susquehanna Health Offers Safe Sitter Course for Tweens and Teens 3Health News:Mayo Clinic genomic analysis lends insight to prostate cancer 2Health News:Dr. Katherine Ahn is Proud to Announce the Launch Her Family's New Charity OCCares 2Health News:Dr. Katherine Ahn is Proud to Announce the Launch Her Family's New Charity OCCares 3Health News:Merrill DataSite Releases New Comments: Trends amidst Canadian and US Tech M&A 2Health News:Merrill DataSite Releases New Comments: Trends amidst Canadian and US Tech M&A 3Health News:Merrill DataSite Releases New Comments: Trends amidst Canadian and US Tech M&A 4
... Adjusted FIFO EBITDA Increased 7.8% to $19.7 Million -- Same-Store ... Improved to $4.3 Million -- Net Loss Improved 18.0% to ... Reade Holdings, Inc. today reported financial results for the first ... , Adjusted ...
... Identifying E. coli, K. pneumoniae and P. aeruginosa ... Results 24-48 Hours Sooner Than Conventional Methods to ... Patients with Gram-Negative Bloodstream InfectionsWOBURN, Mass., and VEDBAEK, ... received FDA 510(k) clearance for EK/ P. aeruginosa ...
... Hills High School ... Nationwide BETHESDA, Md., May 5 The Cystic Fibrosis Foundation ... will visit Vestavia Hills High School in Birmingham, Ala., to honor ... a life-threatening genetic disease. Students raised more than $17,000 for the ...
... Assists Physicians In Identifying Recurrence Risk and the Need ... Clarient, Inc. (Nasdaq: CLRT ... resource for pathologists, oncologists and the pharmaceutical industry, today ... test that helps physicians identify the probability of a ...
... Franklin’s significant words uttered more than 250 years ago ring true ... ... New York, NY (Vocus) May 5, 2009 -– “Out ... 250 years ago ring true for the Gift of Life ...
... Council for Responsible Nutrition Issue Simple Steps to Sleep Better ... stress from economic anxiety mounts, the Better Sleep Council (BSC) ... for Better Sleep Month in May to help consumers enjoy ... best rest possible and help relieve stress, the BSC and ...
Cached Medicine News:Health News:Duane Reade Holdings, Inc. Reports First Quarter 2009 Results 2Health News:Duane Reade Holdings, Inc. Reports First Quarter 2009 Results 3Health News:Duane Reade Holdings, Inc. Reports First Quarter 2009 Results 4Health News:Duane Reade Holdings, Inc. Reports First Quarter 2009 Results 5Health News:Duane Reade Holdings, Inc. Reports First Quarter 2009 Results 6Health News:Duane Reade Holdings, Inc. Reports First Quarter 2009 Results 7Health News:Duane Reade Holdings, Inc. Reports First Quarter 2009 Results 8Health News:Duane Reade Holdings, Inc. Reports First Quarter 2009 Results 9Health News:Duane Reade Holdings, Inc. Reports First Quarter 2009 Results 10Health News:Duane Reade Holdings, Inc. Reports First Quarter 2009 Results 11Health News:Duane Reade Holdings, Inc. Reports First Quarter 2009 Results 12Health News:Duane Reade Holdings, Inc. Reports First Quarter 2009 Results 13Health News:Duane Reade Holdings, Inc. Reports First Quarter 2009 Results 14Health News:Duane Reade Holdings, Inc. Reports First Quarter 2009 Results 15Health News:AdvanDx Receives FDA 510(k) Clearance for EK/P. aeruginosa PNA FISH(R) 2Health News:AdvanDx Receives FDA 510(k) Clearance for EK/P. aeruginosa PNA FISH(R) 3Health News:CW's 7th Heaven Actress Mackenzie Rosman to Visit Birmingham Area High School to Honor Cystic Fibrosis Foundation Fundraising 2Health News:Clarient Launches New Breast Cancer Test 2Health News:Clarient Launches New Breast Cancer Test 3Health News:Clarient Launches New Breast Cancer Test 4Health News:Clarient Launches New Breast Cancer Test 5Health News:Clarient Launches New Breast Cancer Test 6Health News:Bone Marrow Registry to Launch Groundbreaking Fundraising Technology to Overcome Madoff Crisis 2Health News:Stress Keeps Americans Tossing and Turning 2Health News:Stress Keeps Americans Tossing and Turning 3Health News:Stress Keeps Americans Tossing and Turning 4Health News:Stress Keeps Americans Tossing and Turning 5
(Date:5/23/2013)... DIEGO , May 23, 2013 Neurocrine Biosciences, ... Kevin Gorman , President and Chief Executive Officer ... 38 th Annual dbAccess Health Care Conference in Boston.   ... May 30 at 11:20 a.m. Eastern Time / 8:20 a.m. ... accessed on the Company,s website at http://www.neurocrine.com . ...
(Date:5/23/2013)... , May 23, 2013 Hearing health affects a ... younger, and remain socially and professionally engaged, he should address ... overriding message that the Better Hearing Institute (BHI) ... National Men,s Health Week , which leads up to ... runs from June 10 through June 16. ...
(Date:5/23/2013)... , May 23, 2013  Hadasit Bio-Holdings Ltd. (TASE: ... biotech companies, based on intellectual property developed and ... ,s foremost medical research center, today announced ... received significant funding from the Israeli Ministry of ... (OCS) to support product development and advance clinical ...
Breaking Medicine Technology:Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 2Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 3Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 4Hadasit Bio-Holdings Ltd. Portfolio Company - Cell Cure Neurosciences Ltd. Received Additional Government Support 2
... March 19, 2012  New pain medicine and prescription ... Self-Referral Act, can lead to steep penalties and ... advisors with clients in Florida need a clear ... requirements for a statewide prescription drug monitoring database; ...
... Calif., March 19, 2012   Accuray Incorporated (Nasdaq: ... that it has been awarded the 2012 Industry Excellence Award ... Excellence Awards program. Accuray will be honored at ... Monday, March 19, 2012 in Houston, Texas. The ...
Cached Medicine Technology:Navigating New Pain Medicine and Prescription Drug Laws in the Sunshine State 2Navigating New Pain Medicine and Prescription Drug Laws in the Sunshine State 3Navigating New Pain Medicine and Prescription Drug Laws in the Sunshine State 4Accuray Receives Microsoft Dynamics® Customer Excellence Award 2Accuray Receives Microsoft Dynamics® Customer Excellence Award 3Accuray Receives Microsoft Dynamics® Customer Excellence Award 4
... The Series I Instrument program offers ... low profile, while maintaining strength and durability. ... pathology in tight joint spaces. Series I ... cutting tip style, size and angle required ...
... I Instrument program offers state-of-the-art quality in ... maintaining strength and durability. Low profile cutting ... joint spaces. Series I instruments are available ... size and angle required for large and ...
... Punch series facilitates fast and effective resection ... anatomically shaped meniscal rim. The flat, crescent-shaped ... access even the tightest joint spaces. Made ... 20 years of engineering experience in arthroscopy ...
... Punch series facilitates fast and effective resection ... anatomically shaped meniscal rim. The flat, crescent-shaped ... access even the tightest joint spaces. Made ... 20 years of engineering experience in arthroscopy ...
Medicine Products: