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Three Pioneering Ideas in Cancer Research Granted Prestigious Damon Runyon-Rachleff Innovation Awards
Date:1/14/2010

ntify the proteins within cancer cells that are responsible for their altered glucose metabolism.  She aims to grow tumors in mice, then turn off their metabolic "switches," monitoring the result using advanced imaging technologies.   Her research will determine whether targeting tumor metabolism is a feasible approach for cancer therapy and may identify new cancer drug targets.

Dr. Christofk commented, "The field of cancer metabolism has re-emerged with a great deal of promise in the last few years, yet there are several fundamental questions still to be answered.  This award will dramatically accelerate my research and allow me to answer some of these critical questions on a much shorter timetable.  Thank you to the Damon Runyon Cancer Research Foundation and the Rachleffs for their generous support - this award is one of the greatest honors a young scientist could hope for!"

Joshua C. Munger, Ph.D.

University of Rochester, Rochester, New York

Applying a 'systems approach' to understand cancer cell metabolism

Beyond the altered glucose metabolism being studied by Dr. Christofk, cancer induces many other distinctive metabolic activities that are important for cancer cell replication.  

Whereas previous studies often focused on individual metabolic activities, Dr. Munger is taking an expanded "global" approach by
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SOURCE Damon Runyon Cancer Research Foundation
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