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Three Chemo Drugs Better Than Two for Advanced Head/Neck Cancers
Date:10/24/2007

ter in New York City, said that the "triple-drug regimen is more effective than the standard regimen alone when given prior to radiation-based treatment and not at a cost of side effects. There was no increase in overall toxicity."

But, what he said oncologists want to know is whether induction chemotherapy (as was done in these studies) plus chemoradiotherapy is more effective than chemoradiotherapy alone. The addition of induction therapy, said Pfister, adds about three months to the treatment process.

He said studies are currently under way to determine which treatment is best, and, in the meantime, said that chemoradiotherapy alone is the current standard of care.

More information

To learn more about head and neck cancers, visit the National Cancer Institute.



SOURCES: Marshall R. Posner, M.D., associate professor, medicine, and medical director, head and neck oncology program, Dana-Farber Cancer Institute, Boston; David Pfister, M.D., chief, head and neck medical oncology service, Memorial Sloan-Kettering Cancer Center, New York City; Oct. 25, 2007, New England Journal of Medicine


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