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Thomson Reuters Publishes CMR International's 2008 Pharmaceutical R&D Factbook, Now Available for the First Time Online

Output of New Molecular Entities Drops to Historic Low as Pharma Companies

Face Increasing Competition from Generics Companies

LONDON, July 24 /PRNewswire/ -- The Scientific business of Thomson Reuters today announced the availability of the newly published CMR International 2008 Pharmaceutical R&D Factbook, an indispensable reference and business planning tool for decision makers in pharmaceutical R&D, corporate finance, business strategy, marketing planning and corporate communications. This year's Factbook offers a comprehensive and up-to-date overview of emerging trends in worldwide pharmaceutical R&D and has been considerably enhanced with data sourced from other Thomson Reuters businesses providing insight into areas such as generic drugs and patents.

CMR International's research shows that the output of new molecular entities (NMEs) fell to a new 20 year low despite continued year-on-year increases in R&D expenditure. The proportion of sales derived from products first launched within the last five years dropped to below 10%, leaving pharmaceutical companies open to the threat of patent expiry. As R&D companies are attempting to reverse the decline in the Pharma Industry's productivity, it is clear that competition from the generics sector is rapidly increasing. In particular, generics manufacturers in India are having an increased impact.

"The R&D Factbook has highlighted the challenges faced by the pharmaceutical industry, with a decrease in new drugs reaching the marketplace in 2007 and an increasing number of generics manufacturers expanding their capabilities to exploit expiring patents," said Alexander Karle, Vice President and General Manager of CMR International. "Our research shows that those companies best able to manage portfolio risk, drive efficiency through effective development and maximize the return from alliances and collaborations will be best placed to succeed in the coming years."

The information found in the Factbook is based on primary sources covering major pharmaceutical companies that account for approximately 80% of the industry's global R&D expenditure. The CMR International 2008 Pharmaceutical R&D Factbook is available as a hard copy report, or in single-user or enterprise-wide electronic format supplied on CD-ROM.

For further information and an opportunity to purchase the Factbook, please go to:

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