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Thomas Jefferson University Hospital cuts Whipple procedure wound infections in half with new measures
Date:10/26/2011

PHILADELPHIAThomas Jefferson University Hospital surgeons found that a carefully-selected surgical care check list of 12 measures reduced Whipple procedure wound infections by nearly 50 percent.

Smoking cessation at least two weeks prior to surgery, gown and glove change prior to skin closure, and using clippers over razors to shave the surgical area are some of the measures that helped reduced infection rates, according to the study published in the October 26 online issue of the Journal of Surgical Research.

In a retrospective study, Harish Lavu, M.D., assistant professor in the Department of Surgery at Thomas Jefferson University, and colleagues analyzed clinical data from 233 consecutive Whipple procedures -- also known as a pancreaticoduodenectomy, an operation to treat cancerous tumors of the pancreas. -- from October 2005 to May 2008 on patients who underwent routine preoperative preparation (RPP). That preparation is less comprehensive than the 12 measure surgical care bundle. For instance, it uses a razor for hair removal and iodine skin preparation and does not include smoking cessation.

They compared those rates to 233 consecutive Whipple procedures performed from May 2008 to May 2010 following the implementation of the surgical care bundle.

The researchers found a 49 percent reduction in wound infections in the surgical care bundle group (15 percent) compared to the RPP group (7.7 percent). The difference was statistically significant.

"It is typically quite difficult to achieve a 50 percent reduction in an adverse outcome," Dr. Lavu says. "We can make a significant impact on lowering wound infection in patients undergoing this surgery by using this set of guidelines."

Wound infection rates for Whipple procedures are historically higher and mor
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Contact: Steve Graff
stephen.graff@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert  

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