Navigation Links
This week in Blood: Jan. 10, 2013
Date:1/10/2013

Welcome to "This Week in Blood," a weekly snapshot of the hottest studies from each week's issue of Blood, the official journal of the American Society of Hematology (ASH), hand-picked by Blood Editor-in-Chief Bob Lwenberg, MD, and Deputy Editor Nancy Berliner, MD.

Systemic delivery of a TLR7 agonist in combination with radiation primes durable anti-tumor immune responses in mouse models of lymphoma, Dovedi et al.

This week's plenary paper offers a promising potential new immunotherapeutic modality for the treatment of lymphoma. The authors present convincing data to suggest that a toll-like receptor 7 (TLR7) agonist sensitizes tumor cells to radiotherapy. In a mouse model, this increases radiation-induced cell death and prolongs responses.

Model-based decision rules reduce the risk of molecular relapse after cessation of tyrosine kinase inhibitor therapy in chronic myeloid leukemia, Horn et al.

The success of tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia (CML) has led to early investigation of the safety of discontinuing therapy for patients with prolonged deep response to treatment. In this manuscript, Horn and colleagues present a way of predicting the safety of therapy discontinuation.

Biologic and clinical significance of somatic mutations of SF3B1 in myeloid and lymphoid neoplasms, Cazzola et al.

This manuscript, featured as this week's Perspective, discusses how our understanding of the pathophysiology of myelodysplastic syndromes (MDS) and other hematologic malignancies has been transformed over the last year with the discovery of the prevalence and prognostic significance of mutations in genes encoding the cellular splicing machinery.


'/>"/>

Contact: Andrea Slesinski
aslesinski@hematology.org
American Society of Hematology
Source:Eurekalert

Related medicine news :

1. Patient Survival Rises When Drugs Suppress Hepatitis C in Blood: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... ... February 12, 2016 , ... The aging population and ... long term care. With that, says Patrick Loughney, president of Longtree & ... in long term care environments. His company, which offers prep courses and workshops ...
(Date:2/12/2016)... ... February 12, 2016 , ... With the exception of restorative dentistry, to date there has been ... the recent approval by the FDA, there is a now a new protocol in stopping ... is very simple and quick to apply. The application is as simple as drying ...
(Date:2/11/2016)... Los Angeles, CA (PRWEB) , ... February 11, 2016 , ... ... Weight Loss System, a product marketed as a weight loss dietary supplement, is being ... Angeles medical group Beverly Hills Physicians, because there is not a single supplement on ...
(Date:2/11/2016)... ... February 11, 2016 , ... Dr. Sadati’s recent feature in ... Along with performing procedures, the magazine also highlights that Dr. Sadati has pioneered ... of the most common procedures he performs is his natural facelift. “As people ...
(Date:2/11/2016)... ... , ... The president released a FY 2017 budget request on Tuesday that ... the cost burden to military beneficiaries. , MOAA’s president, retired Air Force Lt. ... including limited quantifiable benefit fixes mixed with numerous beneficiary fee hikes. , “We were ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... PORTLAND, Ore. , Feb. 11, 2016 /PRNewswire/ ... pleased to announce the acquisition of SolutionsRx, a full-service ... access hospitals. Along with providing traditional contract pharmacy services, ... to assist clients in navigating the complex 340B regulatory ... of Wellpartner. --> James R. Love , ...
(Date:2/11/2016)... ROLLING MEADOWS , Ill. and INDIANAPOLIS ... major milestone for many young people, but for those ... demanding. Not only do these students juggle class schedules, ... challenges of living with type 1 diabetes. On top ... the first time. Diabetes Scholars Foundation ...
(Date:2/11/2016)... Jeffrey Zucker , vice president of Feasibility ... this year,s Summit for Clinical Operations Executives (SCOPE), being held ... FL. Zucker will discuss how sponsors can rebuild ... "Improving Site Study Activation and Performance" portion of the conference. ... 11:05 a.m. --> --> ...
Breaking Medicine Technology: