Navigation Links
Third trimester group B streptococcus test doesn't accurately predict presence during labor
Date:2/11/2011

SAN FRANCISCO (February 11, 2011) In a study to be presented today at the Society for Maternal-Fetal Medicine's (SMFM) annual meeting, The Pregnancy Meeting , in San Francisco, researchers will present findings that show that many women are having different test results for Group B streptococcus (GBS) between their routine third trimester screening and a rapid test performed at the time of labor.

GBS early-onset sepsis is a leading cause of neonatal infection. GBS is a bacterium that normally exists in the genital tracts of one-third of women; this bacterium comes and goes in the genital tracts of many women often without women knowing that they have it. It can lead to an infection and can put an infant at risk if it is present in the mother during delivery. Women are routinely tested for GBS in their third trimester. If the bacterium is present, these women are given antibiotics during labor. Two days are needed to obtain results from the standard culture, which prevents women from being screened in labor. However, a new rapid test that returns results in approximately one hour can be administered at the time of labor.

"Most women are currently screened for GBS in their last trimester, but even if the test is negative, GBS can still develop before women give birth," said Brett Young, M.D, an obstetrician undergoing training in high risk obstetrics at Massachusetts General Hospital. "We know that two-thirds of infants with GBS sepsis are born to mothers with negative third-trimester cultures, so we wanted to see how many women with a negative GBS test in the third trimester have a positive GBS result right before delivery. These babies in particular are at risk for acquiring GBS infection because the mothers are not given appropriate antibiotics in labor."

Young and her colleagues enrolled women in their study who presented to labor and delivery with an antepartum GBS culture. GBS cultures and rapid tests were performed during labor and compared to the third trimester GBS culture results

Among 559 women, GBS prevalence was 19.5% with the third-trimester culture and 23.8% with culture performed on samples collected during labor. Compared with the culture obtained during labor, the third-trimester culture correctly predicted GBS positivity at the time of labor only 69% of the time versus the rapid test which correctly predicted GBS positivity 91% of the time. The incidence of GBS discordance from the late third trimester to labor was 10%. Compared with women who identified as Caucasian, African-American and Hispanic women were significantly more likely to have discordant culture results.

The study found that the rapid GBS test used when women present in labor has excellent test characteristics and may be a useful adjunct to the third trimester culture for accurately detecting the presence of GBS at the time of labor.

"We found that African-American and Hispanic women were significantly more likely to have results that converted from the third trimester to the time of labor, so the use of the rapid test might be even more beneficial in those groups," said Young.


'/>"/>

Contact: Vicki Bendure
vicki@bendurepr.com
202-374-9259
Society for Maternal-Fetal Medicine
Source:Eurekalert

Related medicine news :

1. Bilingual People More Adept at Learning Third Language
2. Thirdhand smoke may be bigger health hazard than previously believed
3. One-Third of U.S. Adults Could Have Diabetes by 2050: CDC
4. Interactive media improved patients’ understanding of cancer surgery by more than a third
5. Short and long sleep in early pregnancy linked to high blood pressure in the third trimester
6. 10 minutes could prevent one-third of road deaths
7. Third Largest School District in South Carolina to Roll Out More Than 3,500 Aerohive Access Points to Enhance Academic Achievement
8. Nurtur Unveils the Third Dimension in Healthcare at SHRM 2010 Conference in San Diego
9. No Health and Safety Induction for Third of UK Staff
10. One-Third of U.S. Girls Get HPV Vaccine
11. MedStar Hospitals Honored at Obstetric Care Conference: The Third Annual PeriGen Knowledge Summit
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... Austin, TX (PRWEB) , ... June 25, 2016 , ... ... Fellow of the American College of Mohs Surgery and to Dr. Russell Peckham for ... popular and highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic ...
(Date:6/25/2016)... Beach, CA (PRWEB) , ... June 25, 2016 , ... ... UCLA with Magna Cum Laude and his M.D from the David Geffen School of ... Diego and returned to Los Angeles to complete his fellowship in hematology/oncology at the ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published June ... with. The article goes on to state that individuals are now more comfortable seeking ... common operations such as calf and cheek reduction. The Los Angeles area medical group, ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension Association (PHA) ... will receive two significant new grants to support its work to advance research ... anniversary by recognizing patients, medical professionals and scientists for their work in fighting ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain ... for a minimum wage raise to $12 an hour by 2020 and then adjusting it ... the lost value of the minimum wage, assure the wage floor does not erode again, ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... SAN FRANCISCO, Calif. , June 24, 2016 ... GBT ), a biopharmaceutical company developing novel therapeutics ... significant unmet needs, today announced the closing of ... shares of common stock, at the public offering ... shares in the offering were offered by GBT. ...
(Date:6/24/2016)... , June 24, 2016 The Academy ... of recommendations that would allow biopharmaceutical companies ... with entities that make formulary and coverage decisions, a ... "value" of new medicines. The recommendations address ... not appear on the drug label, a prohibition that ...
(Date:6/24/2016)... , June 24, 2016 According ... by Type (Standard Pen Needles, Safety Pen Needles), Needle ... GLP-1, Growth Hormone), Mode of Purchase (Retail, Non-Retail) - ... This report studies the market for the forecast period ... reach USD 2.81 Billion by 2021 from USD 1.65 ...
Breaking Medicine Technology: