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Therapy should extend beyond childhood
Date:7/29/2009

bnormally accumulating metabolites not only give rise to acute, but also to chronic toxic damage. For treatment purposes, this would mean that the duration of current therapy should be extended beyond childhood to prevent long-term changes and damage to the brain. This remains to be elucidated by follow-up studies.

Heidelberg Metabolism Center screens 100,000 newborns annually

Newborn screening in Germany is carried out to detect glutaric aciduria type I and 13 other diseases. The Metabolism Center of the Heidelberg Clinic for Pediatric and Youth Medicine carries out newborn screening for 100,000 newborns annually. The current guidelines in Germany and three other European countries for the diagnosis and therapy of children with this rare metabolic disease were compiled by an international guideline group headed by Dr. Klker. Parallel to this, the same working group carried out translational studies to examine new therapy approaches in a mouse model.


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Contact: Dr. med. Inga Harting
Inga.Harting@med.uni-heidelberg.de
062-215-67564
University Hospital Heidelberg
Source:Eurekalert  

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