Navigation Links
Therapy Could Save Limbs After Frostbite
Date:3/17/2008

Angiography plus anti-clotting drug keep tissue viable, researchers say

MONDAY, March 17 (HealthDay News) -- A new treatment can help save severely frostbitten limbs that might otherwise be amputated, researchers say.

In cases of severe frostbite, deep tissue freezing can damage muscles, tendons, nerves and blood vessels; often leading to gangrene and limb amputation, according to background information in the study.

When severe frostbite occurs, blood vessels are affected and blood flow is blocked. But small clots can also form when the blood vessels are thawed and re-warmed, and spasm of the damaged arteries further obstructs blood flow to the smallest blood vessels, the U.S. team notes.

This study included 17 patients, aged 16 to 65, with severely frostbitten hands and feet. Interventional radiologists used angiography (an X-ray exam of arteries and veins) to identify areas lacking blood flow. They then delivered, via catheter, clot-busting and anti-spasmodic drugs to reopen damaged, clogged arteries.

This approach proved highly successful in saving limbs and preventing amputation. The findings were to be presented Monday at the annual meeting of the Society of Interventional Radiology in Washington, D.C.

"Previously, severe frostbite was a one-way route to limb loss. This treatment is a significant improvement. We're opening arteries that are blocked so that tissue can heal and limbs can be salvaged. We were able to reopen even the smallest arteries, saving patients' fingers and toes," Dr. George Edmonson, an interventional radiologist with St. Paul Radiology, in St. Paul, Minn.

In this study, six patients received the clot-busting drug Tenectaplase while 11 received another drug, Retaplase. The researchers wanted to find out if the greater plasma stability of Tenectaplase would lead to better patient outcomes.

"With both groups, approximately 80 percent of the patients' affected limbs, fingers and toes responded with significant improvement. The treatment has been demonstrated to be safe and beneficial. We will continue research to improve and modify the protocols," Edmonson said.

More information

The MedlinePlus Medical Encyclopedia has more about frostbite.



-- Robert Preidt



SOURCE: Society of Interventional Radiology, news release, March 17, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Vision restoration therapy shown to improve brain activity in brain injured patients
2. HIV therapy in pregnancy-data support WHO recommendations
3. Family-based treatment more effective than supportive psychotherapy in treating bulimia
4. Trial to Test Gene Therapy for Angina in Women
5. One of the Largest Post-WHI Physician Surveys Shows More Education is Needed: Patient Misinformation About Hormone Therapy Remains High
6. Aromatherapy Gift Line Sheds Humorous Light on Modern Therapy
7. Chemotherapy may be culprit for fatigue in breast cancer survivors
8. Atlanta Falcons Physical Therapy Centers Set to Launch This Fall
9. New Drug No Substitute for Standard Blood-Clot Therapy
10. Stem Cell Therapy Disappoints Against Rare Kidney Ailment
11. Nucletron Announces Management Buy-Out to More Effectively Meet the Demands of Its Customers and the Radiation Therapy Community
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Therapy Could Save Limbs After Frostbite
(Date:3/23/2017)... ... 23, 2017 , ... A recent report from the National Council on Teacher ... NCTQ report suggests, based on a review of GPA and SAT/ACT requirements at 221 ... the U.S. It argues that this higher bar should be set by states, by ...
(Date:3/23/2017)... ... March 23, 2017 , ... Texas Physical Therapy ... 960 Gruene Road in Building 2. The clinic is the group’s second in New ... says opening the company’s second New Braunfels location brings things full circle for the ...
(Date:3/23/2017)... ... , ... The MBI “Hall of Fame” recognizes the contributions of those whose careers are or ... the careers of all others involved. , On Monday, March 21st, 2017 Laurie ... of Fame. The induction took place during the World of Modular – Award Gala ...
(Date:3/23/2017)... TX (PRWEB) , ... March 23, 2017 , ... March ... organs that pack a punch when it comes to maintaining good health. Every day, ... 30 minutes, your kidneys filter every drop of your blood, eliminating waste, regulating fluid ...
(Date:3/23/2017)... ... March 23, 2017 , ... ... Angeles based healthcare technology company California Healthcom Group (CHG). , The HUG ... healthcare arena. With headquarters in California, CHG is a growing, internationally recognized healthcare ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)...  The U.S. Food and Drug Administration today granted ... adults and pediatric patients 12 years and older with ... not received prior chemotherapy. This is the first FDA-approved ... skin cancer. "While skin cancer is one ... form called Merkel cell cancer have not had an ...
(Date:3/23/2017)... AUSTIN, Texas , March 23, 2017 /PRNewswire/ ... www.digitalpharmacist.com ), a rapidly growing digital ... PocketRx, a mobile app that allows patients to ... including multi-store locations such as Denver Health Pharmacy, ... app. The acquisition helps Digital Pharmacist accelerate its ...
(Date:3/23/2017)... , March 23, 2017  Interpace Diagnostics Group, ... a fully integrated commercial company that provides clinically ... announced that it has entered into agreements to ... RedPath Shareholders ("RedPath") and concurrently terminate its royalty ... outstanding secured debt to RedPath amounting to $9.34 ...
Breaking Medicine Technology: