Navigation Links
Therapy Could Save Limbs After Frostbite
Date:3/17/2008

Angiography plus anti-clotting drug keep tissue viable, researchers say

MONDAY, March 17 (HealthDay News) -- A new treatment can help save severely frostbitten limbs that might otherwise be amputated, researchers say.

In cases of severe frostbite, deep tissue freezing can damage muscles, tendons, nerves and blood vessels; often leading to gangrene and limb amputation, according to background information in the study.

When severe frostbite occurs, blood vessels are affected and blood flow is blocked. But small clots can also form when the blood vessels are thawed and re-warmed, and spasm of the damaged arteries further obstructs blood flow to the smallest blood vessels, the U.S. team notes.

This study included 17 patients, aged 16 to 65, with severely frostbitten hands and feet. Interventional radiologists used angiography (an X-ray exam of arteries and veins) to identify areas lacking blood flow. They then delivered, via catheter, clot-busting and anti-spasmodic drugs to reopen damaged, clogged arteries.

This approach proved highly successful in saving limbs and preventing amputation. The findings were to be presented Monday at the annual meeting of the Society of Interventional Radiology in Washington, D.C.

"Previously, severe frostbite was a one-way route to limb loss. This treatment is a significant improvement. We're opening arteries that are blocked so that tissue can heal and limbs can be salvaged. We were able to reopen even the smallest arteries, saving patients' fingers and toes," Dr. George Edmonson, an interventional radiologist with St. Paul Radiology, in St. Paul, Minn.

In this study, six patients received the clot-busting drug Tenectaplase while 11 received another drug, Retaplase. The researchers wanted to find out if the greater plasma stability of Tenectaplase would lead to better patient outcomes.

"With both groups, approximately 80 percent of the patients' affected limbs, fingers and toes responded with significant improvement. The treatment has been demonstrated to be safe and beneficial. We will continue research to improve and modify the protocols," Edmonson said.

More information

The MedlinePlus Medical Encyclopedia has more about frostbite.



-- Robert Preidt



SOURCE: Society of Interventional Radiology, news release, March 17, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Vision restoration therapy shown to improve brain activity in brain injured patients
2. HIV therapy in pregnancy-data support WHO recommendations
3. Family-based treatment more effective than supportive psychotherapy in treating bulimia
4. Trial to Test Gene Therapy for Angina in Women
5. One of the Largest Post-WHI Physician Surveys Shows More Education is Needed: Patient Misinformation About Hormone Therapy Remains High
6. Aromatherapy Gift Line Sheds Humorous Light on Modern Therapy
7. Chemotherapy may be culprit for fatigue in breast cancer survivors
8. Atlanta Falcons Physical Therapy Centers Set to Launch This Fall
9. New Drug No Substitute for Standard Blood-Clot Therapy
10. Stem Cell Therapy Disappoints Against Rare Kidney Ailment
11. Nucletron Announces Management Buy-Out to More Effectively Meet the Demands of Its Customers and the Radiation Therapy Community
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Therapy Could Save Limbs After Frostbite
(Date:6/25/2016)... ... , ... Austin residents seeking Mohs surgery services, can now turn to Dr. ... Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to include ... in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar ... M.D from the David Geffen School of Medicine at UCLA. He trained in Internal ... complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had ...
(Date:6/24/2016)... ... 24, 2016 , ... A recent article published June 14 on ... article goes on to state that individuals are now more comfortable seeking to undergo ... such as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills ...
(Date:6/24/2016)... Texas (PRWEB) , ... June 24, 2016 , ... ... International Conference and Scientific Sessions in Dallas that it will receive two significant ... of the grants came as PHA marked its 25th anniversary by recognizing patients, ...
(Date:6/24/2016)... ... 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join ... wage raise to $12 an hour by 2020 and then adjusting it yearly to increase ... of the minimum wage, assure the wage floor does not erode again, and make future ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 Research and Markets ... Electronics 2015-2025: Applications, Technologies, Forecasts" report to ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, Composite ... Structural electronics involves electronic and/or electrical components and ... dumb structures such as vehicle bodies or conformally ...
(Date:6/24/2016)... and SAN CLEMENTE, Calif. , June ... -based mobile pulmonary function testing company, is now able to ... devices developed by ndd Medical Technologies , Inc. ... done in hospital-based labs.  Thanks to ndd,s EasyOne PRO ® , ... , can get any needed testing done in the comfort of ...
(Date:6/24/2016)... LEXINGTON, Mass. , June 24, 2016   ... specialty pharmaceutical company developing innovative inhaled drugs, announced today ... when Russell Investments reconstituted its comprehensive set ... 2016. "This is an important milestone for ... "It will increase shareholder awareness of our progress in ...
Breaking Medicine Technology: