Navigation Links
Therapy Could Save Limbs After Frostbite
Date:3/17/2008

Angiography plus anti-clotting drug keep tissue viable, researchers say

MONDAY, March 17 (HealthDay News) -- A new treatment can help save severely frostbitten limbs that might otherwise be amputated, researchers say.

In cases of severe frostbite, deep tissue freezing can damage muscles, tendons, nerves and blood vessels; often leading to gangrene and limb amputation, according to background information in the study.

When severe frostbite occurs, blood vessels are affected and blood flow is blocked. But small clots can also form when the blood vessels are thawed and re-warmed, and spasm of the damaged arteries further obstructs blood flow to the smallest blood vessels, the U.S. team notes.

This study included 17 patients, aged 16 to 65, with severely frostbitten hands and feet. Interventional radiologists used angiography (an X-ray exam of arteries and veins) to identify areas lacking blood flow. They then delivered, via catheter, clot-busting and anti-spasmodic drugs to reopen damaged, clogged arteries.

This approach proved highly successful in saving limbs and preventing amputation. The findings were to be presented Monday at the annual meeting of the Society of Interventional Radiology in Washington, D.C.

"Previously, severe frostbite was a one-way route to limb loss. This treatment is a significant improvement. We're opening arteries that are blocked so that tissue can heal and limbs can be salvaged. We were able to reopen even the smallest arteries, saving patients' fingers and toes," Dr. George Edmonson, an interventional radiologist with St. Paul Radiology, in St. Paul, Minn.

In this study, six patients received the clot-busting drug Tenectaplase while 11 received another drug, Retaplase. The researchers wanted to find out if the greater plasma stability of Tenectaplase would lead to better patient outcomes.

"With both groups, approximately 80 percent of the patients' affected limbs, fingers and toes responded with significant improvement. The treatment has been demonstrated to be safe and beneficial. We will continue research to improve and modify the protocols," Edmonson said.

More information

The MedlinePlus Medical Encyclopedia has more about frostbite.



-- Robert Preidt



SOURCE: Society of Interventional Radiology, news release, March 17, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Vision restoration therapy shown to improve brain activity in brain injured patients
2. HIV therapy in pregnancy-data support WHO recommendations
3. Family-based treatment more effective than supportive psychotherapy in treating bulimia
4. Trial to Test Gene Therapy for Angina in Women
5. One of the Largest Post-WHI Physician Surveys Shows More Education is Needed: Patient Misinformation About Hormone Therapy Remains High
6. Aromatherapy Gift Line Sheds Humorous Light on Modern Therapy
7. Chemotherapy may be culprit for fatigue in breast cancer survivors
8. Atlanta Falcons Physical Therapy Centers Set to Launch This Fall
9. New Drug No Substitute for Standard Blood-Clot Therapy
10. Stem Cell Therapy Disappoints Against Rare Kidney Ailment
11. Nucletron Announces Management Buy-Out to More Effectively Meet the Demands of Its Customers and the Radiation Therapy Community
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Therapy Could Save Limbs After Frostbite
(Date:2/8/2016)... ... February 08, 2016 , ... GrassrootsHealth published ... rate of type 2 diabetes in the GrassrootsHealth cohort with substantially higher vitamin ... a change in public health,” states Carole Baggerly, Director of GrassrootsHealth, “the safety ...
(Date:2/8/2016)... (PRWEB) , ... February 08, 2016 , ... Guruji Mahendra ... 9th, 10th and 11th, 2016 in honor of his birthday on February 10th. ... happiness. Mahendra Trivedi is known by over 250,000 people from over 40 different ...
(Date:2/7/2016)... ... February 07, 2016 , ... Women's Excellence staff, in all four locations, wore ... Wear Red Day is the first Friday each February and a day to bring ... in 3 deaths among women each year – more than all cancers combined. Go ...
(Date:2/6/2016)... San Rafael, CA (PRWEB) , ... February 06, 2016 , ... ... 2016 Youth Ultimate Coaching Conference (YUCC) . This event brings together top non-profit leaders, ... is “Gender Equity and Girls Ultimate”. Valerio Iani, Bay Area Disc Program Director of ...
(Date:2/5/2016)... ... February 05, 2016 , ... Steven Tonkinson, 36, of Coconut Grove, Florida, ran ... it started in 2003. This year, he ran all 26.2 miles with a green ... team the Miami Heat. , This Sunday, while many are watching the Superbowl, Steven ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)...   GS1 US will hold a series ... GS1 Standards implementation to address the requirements of the ... (UDI) rule. Scott Brown , director ... senior director industry development, medical devices, GS1 US; and ... --> Scott Brown , director ...
(Date:2/8/2016)... NORRITON, Pa. , Feb. 8, 2016 /PRNewswire/ ... of November Research Group (NRG),s pharmacovigilance technology ... pharmacovigilance system-related consulting services and an Oracle Argus ... compliance services to Life Sciences companies. ... strengthens and expands HighPoint,s life sciences capabilities and ...
(Date:2/8/2016)... PALO ALTO, Calif. , Feb. 8, 2016 ... chemical manufacturing, and Kodiak Sciences Inc., a biopharmaceutical company ... retinal disease, announced today agreements for the clinical supply ... manufacture material at multiple sites, including Slough (UK), Visp ... --> Retinal diseases, such as age-related ...
Breaking Medicine Technology: