Navigation Links
Therapeutic cloning treats Parkinson's disease in mice
Date:3/23/2008

NEW YORK, March 23, 2008Research led by investigators at Memorial Sloan-Kettering Cancer Center (MSKCC) has shown that therapeutic cloning, also known as somatic-cell nuclear transfer (SCNT), can be used to treat Parkinsons disease in mice. The studys results are published in the March 23 online edition of the journal Nature Medicine.

For the first time, researchers showed that therapeutic cloning or SCNT has been successfully used to treat disease in the same subjects from whom the initial cells were derived. While this current work is in animals, it could have future implications as this method may be an effective way to reduce transplant rejection and enhance recovery in other diseases and in other organ systems.

In therapeutic cloning or SCNT, the nucleus of a somatic cell from a donor subject is inserted into an egg from which the nucleus has been removed. This cell then develops into a blastocyst from which embryonic stem cells can be harvested and differentiated for therapeutic purposes. As the genetic information in the resulting stem cells comes from the donor subject, therapeutic cloning or SCNT would yield subject-specific cells that are spared by the immune system after transplantation.

The new study shows that therapeutic cloning can treat Parkinsons disease in a mouse model. The scientists used skin cells from the tail of the animal to generate customized or autologous dopamine neuronsthe missing neurons in Parkinsons disease. The mice that received neurons derived from individually matched stem cell lines exhibited neurological improvement. But when these neurons were grafted into mice that did not genetically match the transplanted cells, the cells did not survive well and the mice did not recover.


'/>"/>

Contact: Jeanne D'Agostino
dagostij@mskcc.org
212-639-3573
Memorial Sloan-Kettering Cancer Center
Source:Eurekalert

Page: 1

Related medicine news :

1. Vista Partners Initiates Coverage on Arana Therapeutics (ASX: AAH; AIM: AAHx)
2. Transition Therapeutics to Present at Cowen & Company 28th Annual Healthcare Conference
3. Juvaris BioTherapeutics, Inc. Announces the Appointment of Grant E. Pickering as Chief Executive Officer
4. Echo Therapeutics Announces Positive Results from Symphony(TM) Transdermal Continuous Glucose Monitoring System Study at Tufts Medical Center
5. Cell Therapeutics, Inc. (CTI) Reports Recent Accomplishments and 2007 Fourth Quarter and Year End Financial Results
6. Oracle Healthcare Acquisition Corp. and Precision Therapeutics, Inc. Mutually Terminate Merger Agreement; Oracle Healthcare Acquisition Corp. Cancels Special Meeting
7. Bayer HealthCare and Juvaris BioTherapeutics Announce Major Licensing Agreement
8. Cell Therapeutics, Inc. Announces Issuance of $51.7 Million of New 2012 Convertible Senior Notes
9. Jeffrey Modell Foundation and Talecris Biotherapeutics Expand Diagnostic Services for Primary Immunodeficiencies at Lucile Packard Childrens Hospital at Stanford
10. Nanomedicine system engineered to enhance therapeutic effects of injectable drugs
11. Sirion Therapeutics Receives NDA Acceptance and Priority Review From the FDA for Durezol(TM) in the Treatment of Postoperative Ocular Inflammation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2015)... New York, New York (PRWEB) April 24, 2015 ... continue to move forward in the federal ... of South Carolina. According to court documents, the ... Status Report on April 16th detailing, among other ... The report notes that counsel for both plaintiffs ...
(Date:4/24/2015)... April 24, 2015 The first step ... the mind. , For meditation and yoga teacher Stine ... have been invaluable tools that allow her to experience ... She has been a teacher since 2006, and through ... inner state of being. , “I love sharing this ...
(Date:4/24/2015)... Anchor Health Administrators (Anchor), specialists in ... announced their exclusive agreement with LTC Solutions for All ... distribution partner. , Anchor has more than 18 years ... for associations, and is currently the designated advocate for ... Care Insurance member benefit. , “I am very pleased ...
(Date:4/24/2015)... “Kind,” “selfless,” “the voice of reason” and ... Weiner described pediatric oncology nurse Laura Vasquez of Children’s ... during her five-year battle with a malignant brain tumor. ... and numerous experimental treatments, Vasquez continued caring for Alexa, ... was not in the hospital and even sitting vigil ...
(Date:4/24/2015)... 2015 National Access Cannabis ... access to medical cannabis, is taking a leadership role ... advising patients. , NAC is the first to back ... $250,000 grant, NAC will be providing 300 healthcare professionals ... is to help Canadians gain safe and responsible access ...
Breaking Medicine News(10 mins):Health News:Federal Lipitor Lawsuits Progress, as New Status Report Details Preparation for Upcoming Bellwether Trials 2Health News:Federal Lipitor Lawsuits Progress, as New Status Report Details Preparation for Upcoming Bellwether Trials 3Health News:CURE™ Magazine Names Pediatric Nurse Laura Vasquez from Children’s Hospital Los Angeles As Extraordinary Healer™ of 2015 2Health News:CURE™ Magazine Names Pediatric Nurse Laura Vasquez from Children’s Hospital Los Angeles As Extraordinary Healer™ of 2015 3Health News:CURE™ Magazine Names Pediatric Nurse Laura Vasquez from Children’s Hospital Los Angeles As Extraordinary Healer™ of 2015 4Health News:National Access Cannabis Gives 300 Canadian Healthcare Professionals Access to Medical Cannabis Certificate Program 2
... 5 Longs Drug,Stores Corporation (NYSE: LDG ... the fourth quarter ended January 31, 2008, a,14-week ... share, including a,$1.1 million after-tax net gain related ... from continuing operations for the fourth quarter,ended January ...
... of assessment,and improvement activities for individual physician practices, ... of,Medical Specialties (ABMS) announced today that Blue Cross ... ABMS Patient Safety Improvement,Program to HMO and PPO ... and safety in patient care. BCBSIL is the ...
... March 5 Medifast, Inc.,(NYSE: MED ) announced today ... for the period ended December 31, 2007 on,Wednesday, March 12, ... call and webcast to discuss the results on Thursday, March ... the call by dialing (877) 407-0782 or,(201) 689-8567, or can ...
... first, study finds , , WEDNESDAY, March 5 (HealthDay News) -- ... more likely to become pregnant again within two years of ... study. , The study followed 269 predominately black American, low-income ... five community sites. One or two years after giving birth, ...
... Cancer Society, the American College of Radiology, and ... (a group that comprises representatives from the American ... Society for Gastrointestinal Endoscopy) have released the first-ever ... guidelines add two new tests to the list ...
... when abusive parents with multiple children target just one ... the abused child from the home and return the ... children can suffer lifelong emotional scars from helping parents ... forced to participate in torturing their siblings, according to ...
Cached Medicine News:Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 2Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 3Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 4Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 5Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 6Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 7Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 8Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 9Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 10Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 11Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 12Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 13Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 14Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 15Health News:Blue Cross and Blue Shield of Illinois to Offer ABMS(R) Patient Safety Improvement Program to Network Physicians 2Health News:Blue Cross and Blue Shield of Illinois to Offer ABMS(R) Patient Safety Improvement Program to Network Physicians 3Health News:Medifast, Inc. to Announce Fourth Quarter and Fiscal Year-End Results on Wednesday, March 12, 2008 2Health News:Depression Raised Risk of Subsequent Pregnancies Among Black Teen Moms 2Health News:Health groups issue updated colorectal cancer screening guidelines 2Health News:Health groups issue updated colorectal cancer screening guidelines 3Health News:Authorities fail to recognize emotionally scarred brothers and sisters of child abuse victims 2
(Date:4/23/2015)...  Jazz Pharmaceuticals plc (Nasdaq: JAZZ ) today ... financial results on Thursday, May 7, 2015, after the ... a live audio webcast immediately following the announcement at ... 2015 financial results and provide a business and financial ... audio webcast via the Investors & Media section of ...
(Date:4/23/2015)... BOULDER, Colo. , Apr. 23, 2015 /PRNewswire/ ... engineers, manufactures, and distributes state-of-the art equipment and ... specialization in commercial indoor cannabis cultivation, will host ... on Monday, April 27, 2015, at 4:15 PM ... The conference call will be listen-in ...
(Date:4/23/2015)... Holographic Optical Technologies, innovator in the ... hologram technology available to the consumer market through ... https://www.kickstarter.com/projects/629071847/holographic-optical-technologies?ref=nav_search The company is debuting ... eight-inch Voxbox hologram viewer. This product is offered ... medical-grade unit, the Voxbox Pro. ...
Breaking Medicine Technology:Jazz Pharmaceuticals to Report 2015 First Quarter Financial Results on May 7, 2015 2Surna, Inc. Announces Shareholder Conference Call 2Surna, Inc. Announces Shareholder Conference Call 3Holographic Optical Technologies Launches Kickstarter, Offering True 3D Holograms 2
... Gamma Pharmaceuticals, Inc. (PINKSHEETS: GMPM.PK) a marketing and ... for everyday health and wellness, announced this afternoon, ... Order for the Company,s 17-gram Gamma Energy GEL.  ... value.  Gamma will support sales with point of ...
...   Cerecor Inc. , a biopharmaceutical company focused on ... primary activity is in the human nervous system, today ... FP01 for the treatment of cough has cleared the ... Drug Administration (FDA).  The Company plans to immediately characterize ...
Cached Medicine Technology:Gamma Pharmaceuticals, Inc. Announces Distribution Agreement for New York Tri-state Area and Purchase Order for Gamma Energy GEL™ 2Gamma Pharmaceuticals, Inc. Announces Distribution Agreement for New York Tri-state Area and Purchase Order for Gamma Energy GEL™ 3Cerecor Announces Clearance of IND for FP01 2
... Intersurgical Incorporated manufactures high ... and moisture exchangers, ventilator ... hand-held nebulizers and an ... and connectors for anesthesia ...
... HME product line has the right product ... adults and from intubated patients to patients ... for both anesthesia and critical care applications., ... maximum protection for patients and staff members. ...
Bacterial/Viral Filters for Anesthesia and Respiratory Applications...
Indications For Usage: ,Single patient use on anesthetized patients and respiratory care patients who require a breathing circuit. The product is intended to be replaced at least once every 24 hours...
Medicine Products: