Navigation Links
The small cell neuroendocrine carcinoma of the ampulla of vater
Date:9/24/2008

Ampullary small cell neuroendocrine carcinoma is extremely rare and has only been documented in few case reports and retrospective study. The patients with ampullary small cell neuroendocrine carcinoma usually presented after the age of 60 years, and a male predilection was observed. Only two cases of a small cell neuroendocrine carcinoma associated with an adenoma have been described in a retrospective study. There has been no radiology report describing the imaging features of these coexisting tumors of the ampullary region.

An article published on August 7, 2008 in the World Journal of Gastroenterology addresses this report. The medical team composed of Dr. Sun JH and his colleagues from Second Affiliated Hospital and Sir Run Run Shaw Hospital, Zhejiang University revealed the novel case based on the clinical, histopathological and radiological features.

A 74-year-old man presented with a 3 week history of abdominal discomfort and jaundice. Abdominal ultrasonography, computed tomography (CT) and MR cholangiogram (MRCP) showed two well-defined masses in the ampullary region, dilated bile ducts and pancreatic duct, and peripancreatic lymphadenopathy. The patient underwent Whipple's operation with local lymph node dissection. Histopathology after the operation revealed the coexistence of a small cell neuroendocrine carcinoma and a villous adenoma in the ampulla of Vater. Unfortunately, the patient died of pneumonia 3 months after the operation.

The preoperative diagnosis of these rare tumors in the ampulla is potentially problematic. CT finding of a polypous mass with a long pedicle was helpful to diagnose an adenoma. However, it may not be possible to differentiating ampullary small cell neuroendocrine carcinoma from ampullary adenocarcinoma on CT. Thus, small cell neuroendocrine carcinoma should be included in the differential diagnosis of ampullary masses especially when the patient is an old male. These tumors' associations suggest a common origin in the ampulla of Vater. It is probable that the two neoplasms originate from non-neoplastic multipotent stem cells that terminally differentiate into all kinds of epithelial cells including ciliated cells, mucous cells and endocrine cells.


'/>"/>

Contact: Lai-Fu Li
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Related medicine news :

1. Discoverers of Small Regulatory RNAs and Cholesterol-Lowering Drugs to Receive Lasker Awards for Medical Research
2. Baird Hosts Small Cap Health Care Conference : Senior Healthcare Distribution & Services Research Analyst Eric Coldwell Shares Insights on Sector
3. Conventions Conclude, Fall Campaign Begins: NFIB Looks for More Focus on Small Business Healthcare Concerns
4. Health Insurance Industry Listens to Health Care Concerns of Utah Small Business Owners
5. Managed Compliance Services Program (MCSP) Introduced for Small Healthcare Practitioners
6. Epilepsy drug may help alcoholics recover from dependence, small study suggests
7. Malaria Vaccine Developer Sanaria Inc. and the University of Maryland Biotechnology Institute Awarded Collaborative, Multi-Year, US $600,000 NIH Phase I Small Business Innovation Research Grant
8. The Five Biggest Marketing Mistakes Made By Medical Offices and Small Businesses
9. Mesa Laboratories, Inc. Named to Fortune Small Business Magazines 2008 List
10. Seizures in newborns can be detected with small, portable brain activity monitors
11. PA ABC Health Care Proposal Will Benefit Small Businesses, Revenue Secretary Says
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... ... April 24, 2017 , ... Ridgecrest Herbals makes it a point to lead ... reduce waste, and support renewable energy. They believe this is a crucial part of ... solutions for health issues, and maintain that destroying the environment in the pursuit of ...
(Date:4/24/2017)... Antonio, TX (PRWEB) , ... April 24, 2017 , ... ... by the glitterati, those unreal icons inhabiting the rarified air of pop and film ... the paparazzi and anyone snapping pictures: the smile. Grins now run the gamut from ...
(Date:4/24/2017)... ... April 24, 2017 , ... Sean Fay is the undisputed ... Sonicare Toothbrush, Juiceman Juicer, and the George Foreman Grill (which sold more than 100 ... in the last 25 years. , Now, due to changes in the broadcast media ...
(Date:4/24/2017)... ... April 24, 2017 , ... ALP Nutrition®, ... supplements, announced its popular products are now available for purchase on StackedNutrition.com, a ... the use of premium natural ingredients in making all of its products. These ...
(Date:4/24/2017)... (PRWEB) , ... April 24, 2017 , ... ... advisor within the telehealth industry, announces the company’s VideoMedicine mobile platform has launched ... providers. Available 24 hours a day, Quick Care provides patients with the option ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... Ind. , April 20, 2017  Zimmer Biomet ... in musculoskeletal healthcare, today announced that it will be ... Care Conference at the InterContinental Hotel in ... Zimmer Biomet will present at 11:20 a.m. Eastern Time. ... be accessed via Zimmer Biomet,s Investor Relations website at ...
(Date:4/20/2017)... Research and Markets has announced the addition of the ... Market and Increasing Usage of Complex Biologics during the Forecast Period" ... ... 20 Billion in 2015 to around USD 26 Billion by 2020. ... by Rapidly Expanding Injectables Market and Increasing Usage of Complex Biologics ...
(Date:4/20/2017)... , April 20, 2017  AbbVie (NYSE: ABBV), ... percent (n=145/146) of chronic hepatitis C virus (HCV) ... or 6 and compensated cirrhosis (Child-Pugh A) achieved ... 12 ) with its investigational, pan-genotypic regimen of ... were seen following 12 weeks of G/P treatment ...
Breaking Medicine Technology: