Navigation Links
The science of uncertainty in genomic medicine
Date:2/15/2013

BOSTON - The notion of "personalizing" health care through the use of an individual's genetic code has attracted considerable enthusiasm and investment. Impressive examples, confirmed through formal studies of clinical validity and utility, suggest that we have only scratched the surface of applications to treat disease more precisely, identify risk factors for complex disease, and guide preventative measures.

As the cost of sequencing entire genomes falls, the opportunities for people around the world to take possession of their entire genetic code will proliferate. However, one irony of the precise determination of all 3.2 billion nucleotide pairs is the lack of understanding of the meaning of many sequence variations.

More than 1500 single nucleotide variations are associated with risks for more than 200 complex diseases, but despite their commercialization, these account for a small proportion of heritability of these diseases.

In both translational science and clinical practice, the substantial uncertainty in interpreting genomic information serves as an important barrier to application. Coping with uncertainty can be addressed quantitatively, but how the information is so far understood, presented, and interpreted by physicians and patients has been best addressed qualitatively. Interdisciplinary teams of professionals may be best suited to study the many facets of uncertainty in genomic medicine.

Reed Pyertiz, MD, PhD, the director of Penn CIGHT, the Center for the Integration of Genetic Healthcare Technologies, is moderating a session called, "The Science of Uncertainty in Genomic Medicine," at the 2013 American Association for the Advancement of Science Annual Meeting in Boston, on Friday, February 15, 2013: 10:00 AM-11:30 AM, Room 313, Hynes Convention Center. Pyeritz is available for interviews on the topic of genomic medicine and its uses in clinical care. Penn CIGHT is at the Perelman School of Medicine, University of Pennsylvania.


'/>"/>

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-459-0544
University of Pennsylvania School of Medicine
Source:Eurekalert

Related medicine news :

1. Washingtons Life Sciences Discovery Fund awards commercialization grants
2. Hutchinson Center president elected to American Academy of Art and Sciences
3. Association for Psychological Science, SAGE launch Clinical Psychological Science
4. Ivy Neurological Sciences Internship program funded at TGen
5. UT MD Anderson President Ronald DePinho elected to National Academy of Sciences
6. Understanding and promoting mental health - Insights from psychological science
7. The Science Media Centre, London, wins the 2012 ECNP Media Award
8. Ultra-short laser pulses for science and industry
9. Optogenetics project takes top NIDA Addiction Science Award
10. Psychological Science explains uproar over prostate-cancer screenings
11. The Science of Tasty Tomatoes Lies in the Chemicals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/22/2017)... ... February 22, 2017 , ... Super-Sod will attend the Athens ... in Athens, Georgia. , A shift from Super-Sod’s simple Athens Home Show booth of ... the booth, grass seed plant manager Chris Roquemore constructed furniture from recycled pallet wood ...
(Date:2/22/2017)... ... , ... Social media marketing is transitioning from a singular person activity to ... delves into this insight and more in its latest episode of its Brains Over ... up with social media strategist and partner of the digital firm Med|Ed Digital Jessica ...
(Date:2/22/2017)... ... February 22, 2017 , ... BrightStar Care Charleston , ... the Medical University of South Carolina (MUSC) Center on Aging’s Senior Expo on ... Center on Aging is a tremendous resource in our community. We are thrilled to ...
(Date:2/22/2017)... ... 2017 , ... In a recent article published ... (age, illness and life choices) should be dissociated from medical errors and preventable ... addition, all too often, studies regarding health system performance in other countries, such ...
(Date:2/22/2017)... ... February 22, 2017 , ... ... chain management (SCM) and spend management, today announced that Keppel Corporation has selected ... simplify expense tracking. , “We are excited to announce the partnership between ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... 22, 2017 Orthopedic and cardiac devices ... aging demographic patterns lead to an increasing prevalence ... and exercise-related injuries, chronic back problems, heart valve ... gains. The future of medical implants faces many ... questions and more: - What types of ...
(Date:2/23/2017)... 23, 2017  CTI BioPharma Corp. (CTI BioPharma) (NASDAQ ... report its fourth quarter and full year 2016 financial ... the U.S. financial markets. Following the announcement, members of ... to discuss the results and provide a general corporate ... event can be obtained as follows: Thursday, ...
(Date:2/22/2017)... Calif. , Feb. 22, 2017 IRIDEX ... it will release financial results for the fourth quarter ... March 8, 2017.  The Company,s management team will host ... / 5:00 p.m. ET. Investors interested in ... dialing (844) 707-0665 for domestic callers or (703) 326-3030 ...
Breaking Medicine Technology: