Navigation Links
The science of uncertainty in genomic medicine
Date:2/15/2013

BOSTON - The notion of "personalizing" health care through the use of an individual's genetic code has attracted considerable enthusiasm and investment. Impressive examples, confirmed through formal studies of clinical validity and utility, suggest that we have only scratched the surface of applications to treat disease more precisely, identify risk factors for complex disease, and guide preventative measures.

As the cost of sequencing entire genomes falls, the opportunities for people around the world to take possession of their entire genetic code will proliferate. However, one irony of the precise determination of all 3.2 billion nucleotide pairs is the lack of understanding of the meaning of many sequence variations.

More than 1500 single nucleotide variations are associated with risks for more than 200 complex diseases, but despite their commercialization, these account for a small proportion of heritability of these diseases.

In both translational science and clinical practice, the substantial uncertainty in interpreting genomic information serves as an important barrier to application. Coping with uncertainty can be addressed quantitatively, but how the information is so far understood, presented, and interpreted by physicians and patients has been best addressed qualitatively. Interdisciplinary teams of professionals may be best suited to study the many facets of uncertainty in genomic medicine.

Reed Pyertiz, MD, PhD, the director of Penn CIGHT, the Center for the Integration of Genetic Healthcare Technologies, is moderating a session called, "The Science of Uncertainty in Genomic Medicine," at the 2013 American Association for the Advancement of Science Annual Meeting in Boston, on Friday, February 15, 2013: 10:00 AM-11:30 AM, Room 313, Hynes Convention Center. Pyeritz is available for interviews on the topic of genomic medicine and its uses in clinical care. Penn CIGHT is at the Perelman School of Medicine, University of Pennsylvania.


'/>"/>

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-459-0544
University of Pennsylvania School of Medicine
Source:Eurekalert

Related medicine news :

1. Washingtons Life Sciences Discovery Fund awards commercialization grants
2. Hutchinson Center president elected to American Academy of Art and Sciences
3. Association for Psychological Science, SAGE launch Clinical Psychological Science
4. Ivy Neurological Sciences Internship program funded at TGen
5. UT MD Anderson President Ronald DePinho elected to National Academy of Sciences
6. Understanding and promoting mental health - Insights from psychological science
7. The Science Media Centre, London, wins the 2012 ECNP Media Award
8. Ultra-short laser pulses for science and industry
9. Optogenetics project takes top NIDA Addiction Science Award
10. Psychological Science explains uproar over prostate-cancer screenings
11. The Science of Tasty Tomatoes Lies in the Chemicals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: