A large European consortium has joined forces in the Coordinating Action Systems Medicine CASyM, supported by the FP7- Directorate-General for Research and Innovation of the European Commission, to develop a road map outlining an integrative strategy for the implementation of systems medicine across Europe. This consortium combines extensive experience from its twenty-two partners, including research, higher education and health care organizations, SMEs and pharmaceutical companies, funding bodies as well as research clusters and project management agencies from France, Germany, Iceland, Ireland, Israel, Italy, Luxembourg, the Netherlands, Slovenia, Sweden, and the United Kingdom.
Systems Medicine involves the implementation of systems biology approaches in medical concepts, research and practice, through iterative and reciprocal feedback between data-driven computational and mathematical models as well as model-driven translational and clinical investigations and practice.
The goal of modern systems-based medical research and practice is to intervene at an early stage, to anticipate or prevent the occurrence and reduce the severity of the effects of disease, and to apply limited resources strategically and wisely. This course of action is fundamentally different from the prevailing practice of classical medicine, which is mostly characterized by a reactive approach, whereby intervention only occurs once a disease has already manifested itself. The great potential of systems medicine is to be found in a holistic perspective of each individual patient. In this sense, modern Systems Medicine will be predictive, personalized, participatory and preventive (4P medicine), aiming at a measurable improvement of patient health through a systems based practice.
During the next four years, the CASyM consortium will assess the technological and methodological basis for a European Systems Medicine implementation and will assist the medical community in creatin
|Contact: Dr. Marc Kirschner|
Helmholtz Association of German Research Centres