Navigation Links
The right dose for oncology
Date:3/4/2013

King Mithridates understood that poison is only as good as the dosage taken. Each day, he ingested small quantities of poison in order to become immunize and escape his court's plotters. Oncologists run up against the same principle when fighting cancer. Sometimes, a small dose of chemotherapy may induce dangerous resistance mechanisms in malignant cells, resulting in relapse. Now, EPFL research published in the journal PLOS ONE reports a tool that could simply and accurately determine the right dose for individual patients.

Dosage, a vital issue

This novel tool, developed by Philippe Renaud's team at EPFL, is based on a very simple principle: a cell's electrical conductivity depends on the level of stress induced by chemotherapy. In broad terms, by measuring a cancerous cell's capacity to conduct electricity, researchers can assess the intensity of the treatment's effect.

"When chemotherapy induces very little stress in cells, particularly after the application of a small dose, there is a problem," says Robert Meissner, a co-author of the study. "Not only is its effect not sufficient to kill the affected cells, but this actually increases the risk of inducing resistance, which will eventually make the treatment ineffective."

This is vital during relapse as cells have already developed resistance mechanisms and sometimes oncologists don't have an effective alternative therapy. Hence, it is fundamental to apply the right dose from the start.

Step towards personalized oncology

The method developed at EPFL could help doctors make more patient-specific decisions. "We fully subscribe to the trend of personalized medicine," explains Philippe Renaud. "By making a simple biopsy, oncologists could test the way a particular patient's cells respond to different types of treatments at various doses."

The tool, which was designed for a clinical environment, provides a simple and fast analys
'/>"/>

Contact: Lionel Pousaz
lionel.pousaz@epfl.ch
41-795-597-161
Ecole Polytechnique Fdrale de Lausanne
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Skechers Lawsuit Filed On Behalf of Ohio Woman, Alleging That the Defective Design of Shape-Ups Caused the Plaintiff’s Serious Knee Injuries, by Wright & Schulte
2. Skechers Lawsuit Has Been Filed by Wright & Schulte on Behalf of a Pennsylvania Woman Who Allegedly Sustained Multiple Arm Fractures Allegedly Due to Shape-Ups’ Defective
3. Wright Hip Implant Lawyers at Bernstein Liebhard LLP Note Scheduling of Next Status Conference in Federal Wright Conserve Hip Replacement Litigation
4. NuvaRing Lawsuit Filed on Behalf of a South Carolina Woman who Developed Two Blood Clots While Using NuvaRing, Reports Wright & Schulte LLC
5. Skechers Injury Lawsuit Filed on Behalf of an Alabama Man Who Suffered Severe Leg Fracture Allegedly Due to Skechers Shape-Ups Toning Shoes, by Wright & Schulte LLC
6. To feed the world, give women equal rights
7. Skechers Foot Fracture Lawsuit Filed on Behalf of Nevada Woman Who Suffered a Fracture Allegedly Due to Skechers Shape-Ups Toning Shoes, Reports Wright & Schulte LLC
8. Focal Upright Furniture Announces ErgoDepot as First Retail Partner
9. Dr. Farshchian to Interview Alisha Bright on "Arthritis Show"
10. Can Brightly Colored Fruits, Veggies Protect Against ALS?
11. Brightwater Senior Living of Stonebridge, Saskatoon's Newest Personal Care and Memory Care, Is Proud To Sponsor The Alzheimer Society of Saskatchewan's Walk For Memories
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... Santa Rosa, CA (PRWEB) August 20, 2014 ... is the 12 per diode panel band perfect spectrum that ... plants are most likely to use during photosynthesis. A ... spectral bands is that they almost exclusively reside between 440-480 ... 620-680 on the red side of the spectrum. The KIND ...
(Date:8/20/2014)... 2014 Get the report here: ... presents “Deal Drivers 2014 Half Year Report for the ... activity in both North and South America, with targeted ... Merrill DataSite     , Merrill DataSite is a secure ... due diligence process by providing a highly efficient and ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 Understanding ... governmental and physician stakeholders networks impacting the launch ... America, US, Canada, and Emerging Markets. , This ... Experts’ perspectives on stakeholder management needs for the ... immunotherapy and targeted therapy investigational agents that are ...
(Date:8/20/2014)... Angeles, CA (PRWEB) August 20, 2014 ... it is bringing on Wrench Advisors as a ... tasks including international large accounts. , As Wrench ... sales consultants can help your organization plan and ... executives and global distribution channels. Our experience developing ...
(Date:8/20/2014)... Beach, Florida (PRWEB) August 20, 2014 ... Florida, with the help of their experienced surgeons trained ... of patients to regain their lost or inaccurate vision. ... for performing Lasik surgery is making it possible for ... aging disease which occurs normally in people in the ...
Breaking Medicine News(10 mins):Health News:Cheap LED Grow Lights Are Quickly Being Replaced by Premium Grow Lights 2Health News:Register to Download Merrill DataSite's Report: Deal Drivers 2014 Half Year Report for the Americas 2Health News:Download HeartBeat Experts White Paper: A Stakeholder Engagement Strategy is Critical for the Evolving Melanoma Treatment Setting 2Health News:Biocide Systems Announces Partnership with Wrench Advisors 2Health News:Braverman Eye Center Now Offers Multifocal PresbyLasik in Florida by Trained Surgeons 2
... August 2, 2009 The world,s top lung cancer ... in San Francisco, CA for the 13th World Conference ... for the Study of Lung Cancer (IASLC). Prevention and ... lung cancer remains one of the hardest cancers to ...
... , , , ... around the world are turning to cosmetic surgery in increasing numbers, ... "moobs" ("man boobs".) , , Male cosmetic surgery ... countries where the stigma attached to male cosmetic surgery has all ...
... , MINNEAPOLIS, July 28 Employees ... boots this week as the cooperative put in place a new ... to execute a voluntary recall of instant nonfat dried milk, whey ... new protocols for the dry ingredients production area in preparation for ...
... cell lung cancer (NSCLC) patients over the age of ... erlotinib, Fox Chase Cancer Center researchers reported today at ... Study of Lung Cancer. "Based on our initial ... efficacious, though we,ll have to wait and see the ...
... 1, 2009 The world,s top lung cancer specialists, ... San Francisco, CA for the 13th World Conference on ... the Study of Lung Cancer (IASLC). According to a ... therapies, as first-line treatment, have the potential to slow ...
... ... its entry into the interventional radiology marketplace with the nationwide launch of its new ... ... entry into the interventional radiology marketplace with the nationwide launch of its new ...
Cached Medicine News:Health News:Diagnostic tools and innovative therapies improve patient prognosis 2Health News:Diagnostic tools and innovative therapies improve patient prognosis 3Health News:Diagnostic tools and innovative therapies improve patient prognosis 4Health News:Diagnostic tools and innovative therapies improve patient prognosis 5Health News:Diagnostic tools and innovative therapies improve patient prognosis 6Health News:Men Around the World Seek Cosmetic Surgery 2Health News:Plainview Milk Products Cooperative Implements New Employee Boot Policy 2Health News:Fox Chase finds all-biologic regimen efficacious and well-tolerated in elderly lung cancer patients 2Health News:Advanced targeted therapies effective as first-line treatment for lung cancer 2Health News:Advanced targeted therapies effective as first-line treatment for lung cancer 3Health News:Advanced targeted therapies effective as first-line treatment for lung cancer 4Health News:Advanced targeted therapies effective as first-line treatment for lung cancer 5Health News:Advanced targeted therapies effective as first-line treatment for lung cancer 6Health News:Advanced targeted therapies effective as first-line treatment for lung cancer 7Health News:Advanced targeted therapies effective as first-line treatment for lung cancer 8Health News:New DrainEx(TM) Catheter Simplifies Insertion and Replacement 2
(Date:8/20/2014)... , Aug. 20, 2014 ... research report is available in its ... Hospital-Acquired Infection Control (Sterilization, Disinfection, Testing ... http://www.reportlinker.com/p01618925/The-Market-for-Hospital-Acquired-Infection-Control-Sterilization-Disinfection-Testing-and-Treatment.html Given the ... (HAIs), demand has increased for solutions ...
(Date:8/20/2014)... 20, 2014 Reportlinker.com announces that a ... catalogue: The Impact of Healthcare Reform ... http://www.reportlinker.com/p01618927/The-Impact-of-Healthcare-Reform-PPACA-On-the-US-IVD-Industry.html The "Patient ... complex legislation that affects virtually every aspect of ... beginning to take effect now. IVD manufacturers who ...
(Date:8/20/2014)... Aug. 20, 2014 Reportlinker.com announces ... available in its catalogue: Personal ... Trends and Opportunities to 2018 ... The report provides in depth market analysis, ... accident and health insurance segment, including: - ...
Breaking Medicine Technology:The Market for Hospital-Acquired Infection Control (Sterilization, Disinfection, Testing and Treatment) 2The Market for Hospital-Acquired Infection Control (Sterilization, Disinfection, Testing and Treatment) 3The Market for Hospital-Acquired Infection Control (Sterilization, Disinfection, Testing and Treatment) 4The Market for Hospital-Acquired Infection Control (Sterilization, Disinfection, Testing and Treatment) 5The Market for Hospital-Acquired Infection Control (Sterilization, Disinfection, Testing and Treatment) 6The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 2The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 3The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 4The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 5The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 6Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 2Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 3Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 4Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 5Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 6Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 7Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 8Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 9Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 10Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 11Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 12Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 13Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 14Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 15Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 16Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 17Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 18Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 19Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 20Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 21Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 22Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 23
... Feb. 17, 2012  The Fraxion™ head frame helps ensure ... cancer targets in the brain and cranium. Elekta,s Fraxion ... integrates all proven cranial immobilization options in a single ... years of stereotaxy experience, Fraxion provides the accuracy and ...
... ("CTI") (NASDAQ and MTA: CTIC) announced today that ... opinion for conditional approval from the European Medicines ... Use ("CHMP"). Based on the CHMP,s recommendation, CTI ... should be granted by the European Commission within ...
Cached Medicine Technology:Elekta's Fraxion System Brings Proven Immobilization Options Into One Single Solution for Stereotactic Radiation Therapy of the Brain and Cranium 2European Medicines Agency's Committee For Medicinal Products For Human Use Issues Positive Opinion For Conditional Approval On Marketing Authorization Application For Pixuvri™ 2European Medicines Agency's Committee For Medicinal Products For Human Use Issues Positive Opinion For Conditional Approval On Marketing Authorization Application For Pixuvri™ 3European Medicines Agency's Committee For Medicinal Products For Human Use Issues Positive Opinion For Conditional Approval On Marketing Authorization Application For Pixuvri™ 4European Medicines Agency's Committee For Medicinal Products For Human Use Issues Positive Opinion For Conditional Approval On Marketing Authorization Application For Pixuvri™ 5
... 1100RS Spectrophotometers are simple, ... for use in many ... educational, clinical, industrial and ... COD vial holders, Windows ...
Spectra 2000 Digital Spectrophotometer is designed for quantitative and qualitative analysis in visible range from 320 nm to 1020 nm....
... Series Spectrophotometer is truly ... UV-VIS instrumentation. The latest ... into a radically new ... and performance unprecedented in ...
... Darkfield Quebec Colony Counter allows the user ... choice of models allows for digital counting or ... over the standard lens increasing magnification to 3.0X. ... lens to be raised or lowered. The lens ...
Medicine Products: