Navigation Links
The onchocerciasis parasite showing signs of resistance
Date:1/31/2008

Onchocerciasis is an infection caused by Onchocerca volvulus, a parasite nematode worm transmitted to humans by a species of black fly of the Simulium genus whose larvae develop in fast-flowing rivers. Infected subjects suffer not only from severe skin lesions but also eye damage that can lead to irreversible loss of sight, hence the name river blindness. A huge majorityy -- 99% -- of the 37 million people infected by the parasite live in SubSaharan Africa. Ivermectin, a medicine capable of killing the parasite embryos (the microfilariae) circulating in the organism of patients and temporarily interrupting the nematodes reproduction, is the only treatment used for onchocerciasis control. Since 1995, the African Programme for Onchocerciasis Control (APOC) has been covering 19 of the continents 28 countries hit by the disease. Access to this treatment is possible for 70 million people and has significantly diminished the onchocerciasis-induced morbidity. However, the doubling of cases of infection in certain communities of Ghana between 2000 and 2005, in spite of annual treatments, created fear of the emergence of ivermectin-resistant strains. Such apprehension appears particularly justified in that a high degree of therapeutic cover is achieved during mass distribution campaigns and hence only a tiny part of the parasite population targeted remains unexposed to drug treatment pressure.

Since 1994, a team of IRD researchers, working jointly with Cameroon researchers and others from McGill University of Montreal, has been monitoring a cohort of Cameroon patients benefiting from repeated treatments with ivermectin. Regular parasite sampling from these subjects was performed over a 13-year period in order to determine the changes in the genetic structure of Onchocerca volvulus populations. Each occasion involved measurement of the genotype frequency of heterozygotes and homozygotes for the gene coding β-tubulin, a protein involved in the organiz
'/>"/>

Contact: Gregory Flechet
fichesactu@paris.ird.fr
33-014-803-7607
Institut de Recherche Pour le Dveloppement
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Scientists Map Elephantiasis Parasites Genome
2. Summer Temperatures Linger, Extend Threat of Parasites
3. Parasites a key to the decline of red colobus monkeys in forest fragments
4. To fight disease, animals, like plants, can tolerate parasites
5. Study of malaria parasites reveals new parasitic states
6. Infection With Common Parasite Raises Schizophrenia Risk
7. The New England Journal of Medicine Publishes EURIDIS/ADONIS Study Results Showing Dronedarone Maintained Sinus Rhythm in Patients With Atrial Fibrillation or Flutter With no Observed Pro-Arrhythmia
8. SNM applauds NAS study showing need to restore federal nuclear medicine research funding
9. Clinical Study Published Showing Benefits of Glue Used in Facelift Surgery
10. Research!America Honors Univ. of Chicago Economists for Study Showing Economic Impact of HIV/AIDS Drug Development
11. The Organic Trade Association Hails Preliminary Research Findings Showing Nutritional Benefits of Organic Products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... Washington (PRWEB) , ... July ... ... San Francisco-based Hope Consulting announced today that the two firms have merged ... in the social, health and biopharma sectors. The merger combines SwitchPoint’s strategy ...
(Date:7/7/2015)... (PRWEB) , ... July 07, 2015 , ... The United ... AIDS Action Committee of Massachusetts , and the Multicultural AIDS Coalition $3.78 ... other men who have sex with men (MSM) and transgender women, the groups ...
(Date:7/7/2015)... New York, NY (PRWEB) , ... July 07, 2015 , ... ... , the email newsletter and website that helps active people find the most fun ... health and active lifestyle coverage for millennials. It also increases Greatist’s opportunity for events, ...
(Date:7/7/2015)... ... July 07, 2015 , ... Celestix ... CelestixEdge VE and CelestixFederated VA Series virtual appliances. These virtual platforms expand ... of products, which have proven to simplify the on-premises deployment of unified remote ...
(Date:7/7/2015)... ... , ... Quadrino Law Group is pleased to announce the relocation of the ... The new facility is a state of the art building, located with easy access ... CEO and founder, said, "We are pleased to service our clients from such a ...
Breaking Medicine News(10 mins):Health News:SwitchPoint and Hope Consulting Have Merged to Form Camber Collective 2Health News:CDC Awards Fenway Health, AIDS Action, Multicultural AIDS Coalition $3.78m For ‘Getting To Zero’ HIV Prevention Partnership 2Health News:CDC Awards Fenway Health, AIDS Action, Multicultural AIDS Coalition $3.78m For ‘Getting To Zero’ HIV Prevention Partnership 3Health News:Greatist Acquires Active Lifestyle Brand Blood, Sweat & Cheers 2Health News:Celestix Now Offers Virtual Editions of Its Unified Remote Access and SSO Platforms to Enable Easy Deployment in Virtualized Environments 2Health News:Celestix Now Offers Virtual Editions of Its Unified Remote Access and SSO Platforms to Enable Easy Deployment in Virtualized Environments 3Health News:Celestix Now Offers Virtual Editions of Its Unified Remote Access and SSO Platforms to Enable Easy Deployment in Virtualized Environments 4
... 8, 2009) Carole Wagner Vallianos, Esq., president and ... Medical Center (LA BioMed), will be inaugurated as the president ... Chicago on July 30. Founded in 1913, the American ... lawyers and other members of the public who seek to ...
... REGISTER NOW , , CHICAGO, July 9 ... streets of Chicago, the American Cancer Society Charity Runner Team ... Marathon. , , , "The Society is thrilled ... Chicago Marathon," said Alison Tibbits, project manager, fundraising resources, American ...
... ... power to the Washington Nationals to raise awareness of diabetes and support the creation of a ... , ... -- Nick Jonas of the Jonas Brothers has lent his star power to the Washington Nationals ...
... physicians can improve the health of high-risk patients by ... treatment plan recommendations with primary care physicians, according to ... British Medical Journal. , , The ... can take a more active role in managing the ...
... Hereditary angioedema (HAE) is an autosomal dominant disease ... causes recurrent attacks of intense localized edema involving the ... attenuated androgens or plasmin inhibitors has been the mainstay ... acute treatment are on the horizon. It is important ...
... who had first period before age 12 are at increased risk ... Among women with ovarian cancer, those who had their first menstrual ... menstrual cycles over a lifetime are more likely to die of ... study shows. , U.S. researchers analyzed data on 410 women, aged ...
Cached Medicine News:Health News:LA BioMed President and CEO will be named president of the American Judicature Society 2Health News:Calling All Runners: Join the Fight Against Cancer 2Health News:Nick Jonas Joins with Washington Nationals to Support Children with Diatbetes 2Health News:Kaiser Permanente Project Proves Electronic Health Information and Care Coordination Improve Chronic Disease Management 2Health News:Kaiser Permanente Project Proves Electronic Health Information and Care Coordination Improve Chronic Disease Management 3Health News:Kaiser Permanente Project Proves Electronic Health Information and Care Coordination Improve Chronic Disease Management 4Health News:Changing Paradigms in Hereditary Angioedema: A Focus on Timely Diagnosis and New Therapies 2Health News:Early Menstruation Lowers Odds of Surviving Ovarian Cancer 2Health News:Early Menstruation Lowers Odds of Surviving Ovarian Cancer 3
(Date:7/7/2015)... TORONTO , July 7, 2015   ... device and robotics company with a core focus ... impairments ("Bionik" or the "Company"), announced today that ... accredited investors of units consisting of its common ... approximately US$1.4 million in a private placement transaction. ...
(Date:7/7/2015)... July 7, 2015 Oasmia Pharmaceutical ... within human and veterinary oncology, has filed a registration ... Commission, in connection with the proposed public offering of ... The number of American Depositary Shares, representing ordinary shares, ... offering have not yet been determined. An Investor Roadshow ...
(Date:7/7/2015)...   Abide Therapeutics , a developer of ... dosing of the first subject in a Phase ... endocannabinoid system modulator. ABX-1431 was discovered with Abide,s ... drug candidates that target serine hydrolases, a large ... human physiology and disease. "This is ...
Breaking Medicine Technology:Bionik Laboratories Completes US$13.1 Million Private Placement 2Bionik Laboratories Completes US$13.1 Million Private Placement 3Oasmia Pharmaceutical Files a Registration Statement on Form F-1/A for its Proposed Public Offering and an Application with NASDAQ for a US Listing and Announces Investor Roadshow 2Abide Therapeutics Announces First Subject Dosed in First-in-Human Clinical Study of ABX-1431, an Investigational Endocannabinoid System Modulator 2Abide Therapeutics Announces First Subject Dosed in First-in-Human Clinical Study of ABX-1431, an Investigational Endocannabinoid System Modulator 3
The ACP 215 is the automated closed system cell processor with integrated process control....
... Enhanced Durability for Excellent ... working with challenging cases. PT² ... of a linear elastic nitinol ... resilient polymer tip. This provides ...
... PCS2 system is Haemonetics ... collection of plasma and ... the collection of "jumbo" ... platelet-poor plasma with optional ...
The COBE 2991 Cell Processor provides reliable, automated cell processing, with the control you need to get reproducible results in your lab. This versatile machine offers users reliability and multi...
Medicine Products: