Navigation Links
The new source of islet cells
Date:10/25/2007

The shortage of islet cells limits the development of islet transplantation. One new approach was reported in the October 21 issue of the World Journal of Gastroenterology because of its great significance in enhancing the output of islet cells. This article will undoubtedly bring benefit to diabetic patients.

The article describes the differentiation of rat pancreatic ductal epithelial cells into insulin-producing cells by the transfection of PDX-1. In recent years, though great efforts have been made to differentiate embryonic stem cells, pancreatic ductal epithelial multipotent progenitor cells and bone marrow stem cells into islet cells, the process of cell differentiation and growth is long. Moreover, the amount of islet cells of differentiation, and the insulin released by islets, is not enough to meet the clinical needs.

To shorten the process of differentiation and enhance the output of insulin-producing cells and increase the amount of insulin-releasing, Dr Liu et al. transfected PDX-1 into primary pancreatic ductal epithelial cells and then differentiated the transfected cells into insulin-producing cells. In contrast, the expression of PDX-1 and insulin mRNA and protein were detectable in the transfected cells. Endogenous PDX-1 might play an important role during differentiation and the transfected cells can produce more insulin-releasing cells and release more insulin after induction.

The results of this study suggest a promising future for many diabetic patients who need islets transplantation. Due to the high percentage of diabetes mellitus and severe complications around the world, this case reported by Dr. Liu et al. is surely worth the attention of the researchers of diabetes.


'/>"/>

Contact: You-De Chang
y.d.chang@wjgnet.com
0086-108-538-1892
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. Startling Expose – Physicians Often Have No Regular Source Of Health Car
2. Indian Cherry: Richest Source of Vitiamin C
3. Stem cells - New and richer source found
4. Platelets May Be The Source Of Gene Regulations
5. Walnuts a source of the Anti –oxidant Hormone Melatoni
6. Mushroom found to be a source of a new antibiotic: Plectasin
7. Urban Monkeys Source Of Virus Infections
8. Parents – Teen’s Most Reliable Source for Sex Educatin
9. Singapore’s Healthcare To Outsource To Indian Firm For Faster X-Ray Result
10. ADB To Provide Resources For Combating Bird Flu
11. Investigation to identify the source of HIV infection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/19/2017)... ... January 19, 2017 , ... Allegheny Health Network (AHN) officials today ... access to the Network’s programs and services in the greater Pittsburgh region. Starting January ... will be offered one for that same afternoon. , AHN is ...
(Date:1/19/2017)... , ... January 19, 2017 , ... St. Catherine’s Village ... , Siena Center is a skilled nursing facility on the grounds of the St. ... rooms. It recently was voted the best nursing home in Mississippi for the second ...
(Date:1/19/2017)... CA (PRWEB) , ... January 19, 2017 , ... Bill ... 2017 collaboration with the American Heart Association; “Howe” Healthy is Your Heart Drawing ... stay healthy and active. Each year, Bill Howe Plumbing, Heating & Air receives over ...
(Date:1/19/2017)... ... 19, 2017 , ... Infinity® Massage Chairs announced today that Dan Grover has ... marketing strategies. Grover comes with a total of 15 years experience in consumer goods ... Executive Vice President of Direct Sales at Traeger® Wood Pellet Grills. , Grover ...
(Date:1/18/2017)... DELAWARE (PRWEB) , ... January 18, 2017 , ... Delaware ... 12 in St. Louis, Missouri. , Dickerson, of Laurel, farms about a thousand acres ... string beans, yellow squash on contract and pumpkins and other vegetables for the fresh ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... January 18, 2017 , , Marks E-QURE ... distribution agreement, following similar agreements in Israel ... Wound care is $2 5 billion ... E-QURE Corp. (OTCQB: EQUR), a leader in medical devices for the treatment of ... Médica Equipos Médicos S.A.S. (TeckMedica) in Colombia for the ...
(Date:1/19/2017)... , Jan. 18, 2017 The drug ... billion by 2021 from USD 1,179.20 billion in 2016, ... Increasing prevalence of chronic diseases, increasing demand for ... factors driving the growth of this market. Whereas, self-administration ... generic drugs offer significant growth opportunities for players operating ...
(Date:1/18/2017)... Oregon and PUNE, India , ... published by Allied Market Research, titled, "Breast Imaging Technologies Market ... that the global breast imaging technologies market size was valued ... $4,502 million by 2022, growing at a CAGR of 8.4% ... and Europe together accounted for over ...
Breaking Medicine Technology: